Results 61 to 70 of about 12,832 (181)

Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this class of signaling molecules, primarily due to the introduction of several innovative analytical technologies.
Adolfo Saiardi, Mengsi Lu, Yue Zhang, Anuj Shukla, An‐Li Andrea Ko, Henning J. Jessen   +5 more
wiley   +1 more source

Survey of Smallholder Dairy Cattle Farming System and Antibiotic Residues in Raw Cow's Milk in Bagamoyo District, Tanzania

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Smallholder dairy farmers in Tanzania face livestock disease challenges that drive imprudent antimicrobial use and fuel antimicrobial resistance (AMR). In Bagamoyo, poor husbandry and limited disease control result in high prevalence of vector‐borne infections, commonly treated with oxytetracycline (OTC).
Ridhiwan I. Ramadhani, Hezron Emmanuel Nonga   +1 more
wiley   +1 more source

Profiling Major Livestock Diseases in the East Gojjam Zone, Amhara Region, Ethiopia, Using Participatory Epidemiology Methods

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Participatory epidemiology identified CBPP, LSD, FMD and sheep/goat pox as the major livestock diseases in East Gojjam, Ethiopia, highlighting strong community‐based disease recognition and emphasizing the value of integrating local knowledge into veterinary surveillance and disease control systems.
Liuel Yizengaw Adnie, Haregua Yesigat, Arega Tafere, Kifle Wondimagegnehu, Dessalew Habte, Natenael Teshager, Habtamu Yalew Ayenew, Fentahun Shitaw   +7 more
wiley   +1 more source

Identification of New Anti‐Trypanosoma brucei Leads: An Integrated CRK12‐Guided Virtual Screen With Experimental Validation

Chemical Biology &Drug Design, Volume 108, Issue 3, September 2026.
An integrated computational‐experimental workflow enabled CRK12‐guided hit discovery against Trypanosoma brucei under limited structural and ligand data. The workflow of virtual screening and anti‐T. brucei bioassays identified 4 hit compounds, including three low‐micromolar leads (IC50 = 1.47, 0.81, and 1.33 μM). ABSTRACT Human African trypanosomiasis
Qin Li, Chenggong Fu, Jiayi Luo, Qianqian Zhang, Lingling Wang, Xiaomeng Liu, Jiayue Qiu, Xiaoqing Gong, Henry H. Y. Tong, Xiaojun Yao, Dehua Lai, Huanxiang Liu   +11 more
wiley   +1 more source

Bovines, buffers and barriers: A social scientific perspective on rewilding in the Kavango‐Zambezi Transfrontier Conservation Area

Conservation Science and Practice, Volume 8, Issue 9, September 2026.
Rewilding is often summarized with the three C's of Carnivores, Cores and Corridors. In this essay we propose a complementary perspective that focuses on the three B's of Bovines, Buffers and Barriers. This complementary perspective draws attention to rewilding as a social (rather than only ecological) challenge and is illustrated with insights from ...
Wisse Van Engelen, Paula Alexiou, Manuel Bollmann, Julia Brekl, Emilie Köhler, Léa Lacan, Hauke‐Peter Vehrs, Michael Bollig   +7 more
wiley   +1 more source

Pyridyl‐Thiazole‐Thiosemicarbazones as Antitrypanosomatidae Agents: Design, Synthesis, and In Silico Profiling

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
A novel pyridine–thiazole derivative, Compound 8, exhibited potent dual antitrypanosomatid activity. It demonstrated remarkable in vitro efficacy against Trypanosoma cruzi (IC50 = 1.0 µM) and L. amazonensis (IC50 = 3.9 µM). Molecular docking studies suggested interactions with heme and multiple molecular targets.
Anderson José Firmino Santos da Silva, Daiane Santiago da Cruz Olimpio, Lucas Manoel da Silva Sousa, Graziella Leite Brondani, Tacylla Lima Silva, Wéllyda Belmira de Lira Silva, Natáli Tereza Capistrano Costa, Marcelo Zaldini Hernandes, Policarpo Ademar Sales Junior, Valéria Rêgo Alves Pereira, Ana Cristina Lima Leite   +10 more
wiley   +1 more source

Translocation of livestock‐raiding lions under specific conditions can mitigate conflict

Conservation Science and Practice, Volume 8, Issue 8, August 2026.
Human‐wildlife conflict is a pervasive threat that imperils many carnivore species worldwide, and although translocation is often used as a conflict mitigation strategy, it is widely regarded as ineffective. Here, we demonstrate that careful selection of suitable release sites can improve outcomes, as 80% of stock‐raiding lion translocations in ...
Willem D. Briers‐Louw, João Almeida, Carlos Lopes Pereira, Hugo Pereira, Hagnésio Chiponde, Peter Lindsey, Tamar Kendon, Dário Ngalijuane, Holly Rosier, Jo Taylor, Ellery Worth, Marnus Roodbol, Eugenio Manhiça, David Gaynor, Alison Leslie, Vincent N. Naude   +15 more
wiley   +1 more source

African trypanosomiasis [PDF]

Parasite Immunology, 2011
Morrison, L J; id_orcid 0000-0002-8304-9066, MacLeod, A   +1 more
openaire   +3 more sources

First PATTEC consultative workshop on strategies, technical advances and partnerships in tsetse and trypanosomosis management

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2015
Tsetse and trypanosomiasis (T&T) remain endemic in many countries, although many efforts have been made in recent decades within the framework of the Pan-African Tsetse and Trypanosomiasis Eradication Campaign (PATTEC) Initiative, and despite progress ...
Hassane H. Mahamat
doaj   +1 more source

Chemotherapy of Human African Trypanosomiasis

Interdisciplinary Perspectives on Infectious Diseases, 2009
Human Africa trypanosomiasis is a centuries-old disease which has disrupted sub-Saharan Africa in both physical suffering and economic loss. This article presents an update of classic chemotherapeutic agents, in use for >50 years and the recent ...
Cyrus J. Bacchi
doaj   +1 more source