Results 51 to 60 of about 12,325 (181)

Geographical Variation in the Gut Microbiota of Duttaphrynus melanostictus: Relative Contributions of Environmental Filtering and Host Physiological Modulation

Ecology and Evolution, Volume 16, Issue 7, July 2026.
We examined gut microbial communities in 385 Asian common toads (Duttaphrynus melanostictus) from 14 populations across southern China, using 16S rRNA sequencing to assess the roles of climate, topography, and host traits in shaping community structure.
Di K. Zhu, Nan Wen, Ke Y. Peng, Lin L. Jiang, Jin Li, Li Zhao   +5 more
wiley   +1 more source

Interplay Between Infectious Diseases and the Endocrine System: An Overview and Clinical Insights

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Infectious diseases can disrupt endocrine homeostasis through direct cytopathic injury, autoimmune dysregulation, or pathogen‐derived hormone‐like effects. Viruses and bacteria are the most frequent agents, whereas fungi and parasites contribute less commonly, even remaining clinically relevant, especially in the immunocompromised population.
Francesco Capoccia, Valentina D'Onghia, Valentina Semeraro, Esposito Susanna, Maria Elisabeth Street   +4 more
wiley   +1 more source

Cow Milk Risk Factors Associated With Bacterial Contaminations Along Dairy Value Chain in Lushoto and Handeni Districts, Tanzania

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Milk and milk products are important sources of nutrients to human and animals, but due to its physicochemical characteristics and nutritional value, it serves as an excellent medium for growth of microorganisms. Most of smallholder dairy farmers have no training on livestock husbandry and milk handling practices.
Fortunate Shija, Hezron Emmanuel Nonga
wiley   +1 more source

Host genetics in African trypanosomiasis

Infection, Genetics and Evolution, 2008
In Africa, the protozoan parasite of the genus Trypanosoma causes animal (AAT) and human African trypanosomiasis (HAT). These diseases are responsible for considerable mortality and economic losses, and until now the drugs commonly used have often been very toxic and expensive, with no vaccine available.
Courtin, D., Berthier, D., Thevenon, S., Dayo, G. K., /Garcia, André, /Bucheton, Bruno   +5 more
openaire   +4 more sources

An Atypical Aquaporin 1 Derived From Paramecium multimicronucleatum Functions as a Multifunctional Channel That Permeates Water, Glycerol, and Urea

Journal of Eukaryotic Microbiology, Volume 73, Issue 4, July/August 2026.
ABSTRACT Although it had been reported that the translation product of the functional aquaporin gene, aqp1, is localized to the contractile vacuole complex of Paramecium multimicronucleatum, the molecules that pass through this channel protein had not been identified. In the present study, we introduced and expressed this protein in Xenopus oocytes and
Masaki Ishida, Shuichi Ueno, Takashi Tominaga, Kurumi Tanaka, Akito Horikawa, Manabu Hori   +5 more
wiley   +1 more source

Cost analysis of options for management of African Animal Trypanosomiasis using interventions targeted at cattle in Tororo District; south-eastern Uganda

Parasites & Vectors, 2015
Background Tsetse-transmitted African trypanosomes cause both nagana (African animal Trypanosomiasis-AAT) and sleeping sickness (human African Trypanosomiasis - HAT) across Sub-Saharan Africa.
Dennis Muhanguzi, Walter O. Okello, John D. Kabasa, Charles Waiswa, Susan C. Welburn, Alexandra P.M. Shaw   +5 more
doaj   +1 more source

African animal trypanosomiasis as a constraint to livestock health and production in Karamoja region: a detailed qualitative and quantitative assessment

BMC Veterinary Research, 2017
Background Nagana (African Animal Trypanosomiasis-AAT) and tick-borne diseases (TBDs) constrain livestock production in most parts of sub-Saharan Africa.
Dennis Muhanguzi, Albert Mugenyi, Godfrey Bigirwa, Maureen Kamusiime, Ann Kitibwa, Grace Gloria Akurut, Sylvester Ochwo, Wilson Amanyire, Samuel George Okech, Jan Hattendorf, Robert Tweyongyere   +10 more
doaj   +1 more source

African trypanosomes

Parasites & Vectors, 2019
African trypanosomes cause human African trypanosomiasis and animal African trypanosomiasis. They are transmitted by tsetse flies in sub-Saharan Africa.
Mathieu Cayla, Federico Rojas, Eleanor Silvester, Frank Venter, Keith R. Matthews   +4 more
doaj   +1 more source

Anti-Trypanosomal Proteasome Inhibitors Cure Hemolymphatic and Meningoencephalic Murine Infection Models of African Trypanosomiasis

Tropical Medicine and Infectious Disease, 2020
Current anti-trypanosomal therapies suffer from problems of longer treatment duration, toxicity and inadequate efficacy, hence there is a need for safer, more efficacious and ‘easy to use’ oral drugs.
Srinivasa P S Rao, Suresh B Lakshminarayana, Jan Jiricek, Marcel Kaiser, Ryan Ritchie, Elmarie Myburgh, Frantisek Supek, Tove Tuntland, Advait Nagle, Valentina Molteni, Pascal Mäser, Jeremy C Mottram, Michael P Barrett, Thierry T Diagana   +13 more
doaj   +1 more source

Exploring 6‐Hydroxy‐3‐Aryl/Heteroarylcoumarins as Promising Candidates Against Trypanosoma cruzi

ChemMedChem, Volume 21, Issue 9, 14 May 2026.
New therapies are urgently needed for Chagas disease, and screening of 6‐hydroxy‐3‐aryl/heteroarylcoumarin derivatives identified highly selective compounds with potent activity against T. cruzi. In particular, derivative 1f showed submicromolar trypomastigote potency, dual‐stage activity, and inhibition of amastigote‐to‐trypomastigote differentiation,
C. N. Pereira, L. da Silva Lara, S. da Costa Lanera, T. Pérez de Souza, M. C. de Souza Pereira, G. L. Delogu, M. Silva dos Santos, M. J. Matos   +7 more
wiley   +1 more source