Results 51 to 60 of about 12,832 (181)

Local Solutions to Structural Issues: The Fetishization of Custom in Rural Development Interventions in Côte d'Ivoire

Journal of Agrarian Change, EarlyView.
ABSTRACT This paper explores the paradox of seeking local solutions in rural development when conflicts result from structural transformations of the agrarian economy driven by national political choices. Since the 1990s, participatory approaches inspired by neo‐institutionalist theories of local governance have encouraged development actors to view ...
Toni‐Giovanni Pegurri
wiley   +1 more source

Garlic‐Derived Behavioural Deterrents: Diallyl Disulfide and TrpA1‐Mediated Suppression of Insect Reproduction

Modern Agriculture, Volume 4, Issue 2, December 2026.
Garlic‐derived diallyl disulfide acts as a behavioural deterrent that suppresses insect mating and oviposition through sensory pathways. The compound is detected through gustatory mechanisms involving the transient receptor potential A1 (TrpA1) channel and neural responses.
Sumit Singh, Shaoying Wu
wiley   +1 more source

Human African trypanosomiasis

, 2013
Human African trypanosomiasis or sleeping sickness is a neglected tropical disease that affects populations in sub-Saharan Africa. The disease is caused by infection with the gambiense and rhodesiense subspecies of the extracellular parasite Trypanosoma brucei, and is transmitted to humans by bites of infected tsetse flies.
Lejon, Veerle, Bentivoglio, M., Franco, J.R.   +2 more
openaire   +4 more sources

Drug Discovery for Snakebite Envenoming: Wanderings Amid Historical Antidotes and Emerging Therapeutic Opportunities

ChemMedChem, Volume 21, Issue 21, 12 November 2026.
In this review, we provide an overview of selected historical antidotes against snakebite envenomation used in early modern Europe. Then, the evidence‐based antivenom activity of some natural compounds is discussed as resulting from more than two decades of research studies.
Elisa Bianconi, Emidio Camaioni, Paulina Oszajca, Antonio Macchiarulo   +3 more
wiley   +1 more source

HIV‐associated nephropathy: A decade of clinical outcomes, global disparities and emerging promise

HIV Medicine, Volume 27, Issue 11, Page 1753-1762, November 2026.
Abstract Objective To review the pathogenesis, epidemiology, clinical presentation, management and outcomes of HIV‐associated nephropathy (HIVAN), with emphasis on global disparities, genetic susceptibility (APOL1) and emerging therapeutic and technological advances.
Deepak V. Pathiyil, Nicola Wearne, Brendon Price, Frank Post, Dami A. Collier   +4 more
wiley   +1 more source

Human African trypanosomiasis

The Lancet, 2017
Human African trypanosomiasis (sleeping sickness) is a parasitic infection that almost invariably progresses to death unless treated. Human African trypanosomiasis caused devastating epidemics during the 20th century. Thanks to sustained and coordinated efforts over the past 15 years, the number of reported cases has fallen to an historically low level.
Buscher, P., Cecchi, G., /Jamonneau, Vincent, Priotto, G.   +3 more
openaire   +3 more sources

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

Advanced Science, Volume 13, Issue 59, 23 October 2026.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa, Hui Yuan, Jingui Ma, Zhigang Yang, Mei Wang, Weibiao Wang, Lingling Yang, Fen Ma, Weiman Zhang, Gidion Wilson Mening'oo, Guoning Chen, Xueqin Ma   +11 more
wiley   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, Volume 7, Issue 5, October 2026.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Community Health Workers' Multiple Understandings of Schistosomiasis Transmission Pathways: Exploring Contextual Factors in Côte d'Ivoire, Kenya and Uganda

Tropical Medicine &International Health, Volume 31, Issue 10, Page 1453-1464, October 2026.
ABSTRACT Objective Schistosomiasis remains a public health concern in sub‐Saharan Africa, affecting over 250 million people. In endemic settings, schistosomiasis transmission is not always understood exclusively in biomedical terms. Community health workers (CHWs) contribute to schistosomiasis control through mass drug administration and health ...
Dianne Verhoeven, Lisa Sophie Reigl, Alice Sereti Sinkeet, Mary Maghanga, Alexise Djouquou Gnahore, Bi Tra Jamal Sehi, Suzanne Lobohon Lavry, Andrea Buhl, Marie Frese, Jennifer Burrill, Eveline Hürlimann, Peter Steinmann, Nora Monnier, Ashley Preston, Janet Masaku, Matthias Richter, Mary Amuyunzu Nyamongo, Alain Toh, Stella Neema, Isabelle L. Lange, Andrea S. Winkler, on behalf of the Pediatric Praziquantel Consortium   +21 more
wiley   +1 more source

Host genetics in African trypanosomiasis

Infection, Genetics and Evolution, 2008
In Africa, the protozoan parasite of the genus Trypanosoma causes animal (AAT) and human African trypanosomiasis (HAT). These diseases are responsible for considerable mortality and economic losses, and until now the drugs commonly used have often been very toxic and expensive, with no vaccine available.
Courtin, D., Berthier, D., Thevenon, S., Dayo, G. K., /Garcia, André, /Bucheton, Bruno   +5 more
openaire   +4 more sources