Results 61 to 70 of about 1,269 (154)

The Dietary Polyphenol Resveratrol in Intestinal Ischemia–Reperfusion Injury: From Multifaceted Protective Mechanisms to Clinical Translation Challenges

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
Intestinal ischemia–reperfusion (I/R) injury is a life‐threatening condition with mortality approaching 50%, driven by oxidative stress, inflammatory cascades, ferroptosis, and intestinal barrier disruption that ultimately precipitates distant organ dysfunction.
Xue‐feng Zhang, Zhi Huang, Yuan Zeng, Yan Zhang, Ping Li, Fei‐xiang Wang, Liang Nie   +6 more
wiley   +1 more source

Mast Cell‐Derived CXCL4: A Key Mediator of Ferroptosis and Cardiac Damage in Septic Cardiomyopathy

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
ABSTRACT Background Septic cardiomyopathy (SCM) is a common and life‐threatening complication of severe sepsis, with high mortality due to unclear underlying mechanisms. CXCL4, a key pro‐inflammatory factor, is implicated in various heart diseases, while ferroptosis (iron and lipid hydrogen peroxide‐dependent regulated cell death) plays a crucial role ...
Jing Wei, Zhi‐ying Jiang, Ling‐feng Ye, Hong‐xiang Lu   +3 more
wiley   +1 more source

From Pharmaceutical to Biophysical Therapies: New Horizons in Inflammatory Bowel Disease Management

JCC Plus, Volume 1, Issue 2, March 2026.
Important limitations exist in the current pharmacological landscape of Inflammatory Bowel Disease (IBD), such as variable response rates and treatment‐limiting adverse effects. In this review, we perform a critical assessment of the current literature on novel multimodal biophysical approaches showing alternative mechanisms of action to, and potential
Benedetta Ricchi, Alejandra A. Carriles, Samuel Elias Pineda Chavez, Stefanos Bonovas, Arianna Dal Buono, Cristina Bezzio, Alessandro Armuzzi, Stefania Vetrano   +7 more
wiley   +1 more source

Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients

Clinical &Experimental Allergy, Volume 56, Issue 3, Page 227-242, March 2026.
Dupilumab therapy reduced elevated type 2 cytokine responses post‐ASA provocation in N‐ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 immunity. Transcriptomic analysis showed concurrent downregulation of lipid and peroxisome pathways during ASA challenge in N‐ERD patients after 24 weeks of
Julia Eckl‐Dorna, Christina Morgenstern, Katharina Poglitsch, Tamara Arnoldner, Katharina Gangl, Tina J. Bartosik, Nicholas J. Campion, Aldine Tu, Victoria Stanek, Sven Schneider, Christine Bangert   +10 more
wiley   +1 more source

Atypical mast cells and multiple myeloma: An ambiguous alliance with diagnostic implications

British Journal of Haematology, Volume 208, Issue 3, Page 817-818, March 2026.
Jean‐Baptiste Rieu, Anaïs Schavgoulidze, Alban Canali, Laetitia Largeaud, Aurore Perrot, Charlotte Syrykh   +5 more
wiley   +1 more source

Tryptase [PDF]

, 2020
openaire   +1 more source

Genetic Variants Leading to Urticaria and Angioedema and Associated Biomarkers. [PDF]

J Allergy Clin Immunol Pract, 2023
Lyons JJ, Farkas H, Germenis AE, Rijavec M, Smith TD, Valent P.   +5 more
europepmc   +1 more source

Hereditary Alpha-Tryptasemia and Mastocytosis: What We Know and What We Need To Learn. [PDF]

Curr Allergy Asthma Rep
Rama TA, Gulen T.
europepmc   +1 more source

Immunomodulation of Myocardial Fibrosis. [PDF]

JACC Basic Transl Sci, 2023
Sikking MA, Stroeks SLVM, Marelli-Berg F, Heymans SRB, Ludewig B, Verdonschot JAJ.   +5 more
europepmc   +1 more source

Reviewing the Peripheral and Central Mechanisms of Visceral Hypersensitivity in Intestinal Disorders. [PDF]

Int J Med Sci
Tang W, Wang J, Wang W, Xue J, Wang Y, Jiang F, Kechiyerunda DC, Gao S, Yuan T, Guo F.   +9 more
europepmc   +1 more source