Results 121 to 130 of about 504,978 (306)

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

Advanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane, Lyn I. Jones, Richard M. Martin, Helen Winter, Faezeh Arab Hassani   +4 more
wiley   +1 more source

Tryptophan metabolism in health and disease.

Cell Metabolism, 2023
Chen Xue, Ganglei Li, Q. Zheng, Xin-yu Gu, Qing-miao Shi, Yuanshuai Su, Qingfei Chu, Xin Yuan, Zhengyi Bao, Juan-fen Lu, Lanjuan Li   +10 more
semanticscholar   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

2‐line Ferrihydrite Enhance Microbial Synthesis of Plant Biostimulants in Composted Biosolid by Regulating Phyla Pseudomonadota and Actinomycetota

Advanced Science, EarlyView.
This study explores how iron and manganese oxides transform sewage sludge into plant biostimulants during composting. Non‐targeted identification reveals the main species of plant biostimulants. Metagenomic analysis reveals that 2‐line ferrihydrite specifically enriches microbial genes for biosynthesis, boosting plant‐growth promoters.
Yu Zhang, Ziwei Zhang, Zexu Chen, Boyuan Yang, Siying Cai, Jun Chen, Jianhua Guo, Weijun Zhang   +7 more
wiley   +1 more source

Dietary Tryptophan Requirement of Juvenile Hybrid Grouper (Epinephelus fuscoguttatus♀ × E. lanceolatus♂)

Animals
A 10-week feeding study was conducted to examine the effects of dietary tryptophan (Trp) levels on the growth performance and protein metabolism of hybrid grouper (Epinephelus fuscoguttatus♀ × E.
Jiaxian Chen, Xiaohui Dong, Qihui Yang, Shuyan Chi, Shuang Zhang, Beiping Tan, Junming Deng   +6 more
doaj   +1 more source

Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases.

Gastroenterology, 2017
BACKGROUND & AIMS Administration of tryptophan and some of its metabolites reduces the severity of colitis in mice, whereas removing tryptophan from the diet increases susceptibility to colitis.
S. Nikolaus, B. Schulte, Natalie Al-Massad, F. Thieme, D. Schulte, J. Bethge, A. Rehman, F. Tran, K. Aden, R. Häsler, N. Moll, G. Schütze, M. Schwarz, G. H. Waetzig, P. Rosenstiel, M. Krawczak, S. Szymczak, S. Schreiber   +17 more
semanticscholar   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Association of tryptophan pathway metabolites with mortality and effectiveness of nutritional support among patients at nutritional risk: secondary analysis of a randomized clinical trial

Frontiers in Nutrition
Tryptophan is an essential amino acid and is the precursor of many important metabolites and neurotransmitters. In malnutrition, the availability of tryptophan is reduced, potentially putting patients at increased risks.
Jacqueline Ritz, Jacqueline Ritz, Carla Wunderle, Franziska Stumpf, Rahel Laager, Rahel Laager, Pascal Tribolet, Pascal Tribolet, Pascal Tribolet, Peter Neyer, Luca Bernasconi, Zeno Stanga, Beat Mueller, Beat Mueller, Philipp Schuetz, Philipp Schuetz   +15 more
doaj   +1 more source

Tryptophan Metabolism by Gut Microbiome and Gut-Brain-Axis: An in silico Analysis

Frontiers in Neuroscience, 2019
The link between gut microbiome and brain is being slowly acknowledged due to the speculated role of resident gut microbial community in altering the functions of gut-brain axis (GBA).
Harrisham Kaur, Chandra Bose, S. Mande
semanticscholar   +1 more source

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source