Results 31 to 40 of about 222,637 (336)
Nanosensor detection of an immunoregulatory tryptophan influx/kynurenine efflux cycle.
PLoS Biology, 2007 Mammalian cells rely on cellular uptake of the essential amino acid tryptophan. Tryptophan sequestration by up-regulation of the key enzyme for tryptophan degradation, indoleamine 2,3-dioxygenase (IDO), e.g., in cancer and inflammation, is thought to ...
Thijs Kaper +5 more
doaj +1 more source
Tryptophan Dietary Impacts Gut Barrier and Metabolic Diseases
Frontiers in Immunology, 2019 The intestine has a major role in the digestion and absorption of nutrients, and gut barrier is the first defense line against harmful pathogens. Alteration of the intestinal barrier is associated with enhanced intestinal permeability and development of ...
Soraya Taleb
doaj +1 more source
Tryptophan-containing proteins as label-free nanothermometers [PDF]
arXiv, 2021 There remains a need for techniques to monitor thermal processes at high spatiotemporal resolution, with myriad potential applications in chemistry, biology, and engineering. Measurement of temperature from nanoscale molecular phenomena are particularly promising due to their general compatibility with biological systems.
arxiv
Purcell radiative rate enhancement of label-free proteins with ultraviolet aluminum plasmonics [PDF]
, 2021 The vast majority of proteins are intrinsically fluorescent in the ultraviolet, thanks to the emission from their tryptophan and tyrosine amino-acid constituents. However, the protein autofluorescence quantum yields are generally very low due to the prevailing quenching mechanisms by other amino acids inside the protein.
arxiv +1 more source
Boolean models of the transport, synthesis, and metabolism of tryptophan in Escherichia Coli [PDF]
arXiv, 2022 The tryptophan (trp) operon in E. coli codes for the proteins responsible for the synthesis of the amino acid tryptophan from chorismic acid, and has been one of the most well-studied gene networks since its discovery in the 1960s. The tryptophanase (tna) operon codes for proteins needed to transport and metabolize it.
arxiv
A systematic study of the valence electronic structure of cyclo(Gly-Phe), cyclo(Trp-Tyr) and cyclo(Trp-Trp) dipeptides in gas phase [PDF]
, 2021 The electronic energy levels of cyclo(Glycine-Phenylalanine), cyclo(Tryptophan-Tyrosine) and cyclo(Tryptophan-Tryptophan) dipeptides are investigated with a joint experimental and theoretical approach. Experimentally, valence photoelectron spectra in the gas phase are measured using VUV radiation.
arxiv +1 more source
Entropy, 2013 Glyphosate, the active ingredient in Roundup®, is the most popular herbicide used worldwide. The industry asserts it is minimally toxic to humans, but here we argue otherwise.
Anthony Samsel, Stephanie Seneff
doaj +1 more source
A synopsis of recent work on the amino acid nutrition of layers1
Journal of Applied Poultry Research, 2021 Summary: This review, a summation of work presented at the Virtual 2020 Poultry Science Association Annual Meeting, addresses changes in laying hen performance and techniques to manage hens that require fine-tuning amino acid minimums.
M.T. Kidd, R.E. Loar, II
doaj
IDO Expression in Cancer: Different Compartment, Different Functionality?
Frontiers in Immunology, 2020 Indoleamine 2,3-dioxygenase 1 (IDO1) is a cytosolic haem-containing enzyme involved in the degradation of tryptophan to kynurenine. Although initially thought to be solely implicated in the modulation of innate immune responses during infection ...
Annabel Meireson +4 more
doaj +1 more source
Electronic Energy Migration in Microtubules [PDF]
arXiv, 2022 The repeating arrangement of tubulin dimers confers great mechanical strength to microtubules, which are used as scaffolds for intracellular macromolecular transport in cells and exploited in biohybrid devices. The crystalline order in a microtubule, with lattice constants short enough to allow energy transfer between amino acid chromophores, is ...
arxiv