Results 11 to 20 of about 1,087,731 (295)

Tryptophan metabolism in depression [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 1970
Psychiatric patients suffering from endogenous depression and a control group without endogenous depression were given oral loads of L-tryptophan and urinary excretion determined of the tryptophan metabolites on the pyrrolase pathway: kynurenine, 3-hydroxykynurenine, and 3-hydroxyanthranilic acid.
G, Curzon, P K, Bridges
openaire   +3 more sources

Tryptophan Metabolism in Rabbits

open access: yes, 2003
Enzyme activities involved in tryptophan metabolism along the kynurenine pathway were studied in male New Zealand white rabbits. Activities are expressed both as specific activity and per g of fresh tissue. Liver tryptophan 2,3-dioxygenase activity (TDO), when assayed in either the absence (holoenzyme) or presence of added haematin (apoenzyme), did not
ALLEGRI, GRAZIELLA   +4 more
openaire   +4 more sources

The Engagement of Cytochrome P450 Enzymes in Tryptophan Metabolism

open access: yesMetabolites, 2023
Tryptophan is metabolized along three main metabolic pathways, namely the kynurenine, serotonin and indole pathways. The majority of tryptophan is transformed via the kynurenine pathway, catalyzed by tryptophan-2,3-dioxygenase or indoleamine-2,3 ...
Anna Haduch   +3 more
doaj   +2 more sources

Tryptophan Metabolism and Gut Microbiota: A Novel Regulatory Axis Integrating the Microbiome, Immunity, and Cancer

open access: yesMetabolites, 2023
Tryptophan metabolism and gut microbiota form an integrated regulatory axis that impacts immunity, metabolism, and cancer. This review consolidated current knowledge on the bidirectional interactions between microbial tryptophan processing and the host ...
Yingjian Hou, Jing Li, Shuhuan Ying
doaj   +2 more sources

Altered Tryptophan and Neopterin Metabolism In Cancer Patients

open access: yesPteridines, 1998
Plasma 5-hydroxytryptamine (serotonin), tryptophan and neopterin levels were measured in patients with depressive cancer cachexia and in healthy controls during the same time period.
Iwagaki Hiromi   +3 more
doaj   +2 more sources

Toll-like Receptor Activation Remodels the Polyamine and Tryptophan Metabolism in Porcine Macrophages

open access: yesMetabolites
Background: The early nutritional metabolism of piglets is intimately associated with the regulation of immune function, and amino acids play a crucial role in modulating the fate and function of porcine immune cells, especially macrophages. However, the
Meimei Zhang   +3 more
doaj   +2 more sources

Tryptophan metabolism in liver transplantation immune tolerance. [PDF]

open access: yesFront Immunol
Liver transplantation is a life-saving treatment for end-stage liver disease, but long-term outcomes are limited by complications of lifelong immunosuppression. Inducing immune tolerance has become a major research priority.
Li W, Ren A.
europepmc   +2 more sources

A Defect in Tryptophan Metabolism [PDF]

open access: yesPediatric Research, 1976
Oral tryptophan loading tests were performed in a patient with photosensitive pellagra-like skin rash and cerebellar ataxia but without hyperaminoaciduria. Plasma tryptophan concentrations after loading were similar in the patient and control subjects.
P W, Wong   +3 more
openaire   +2 more sources

Metabonomic Study of the Involvement of the Intestinal Microflora in the Improvement of Iron Deficiency Anemia (IDA) by Auricularia auricula Melanin in Mice [PDF]

open access: yesShipin Kexue, 2023
Iron deficiency anemia (IDA) is a common iron deficiency disease. IDA has become one of the major public health problems worldwide. Our previous studies have shown that Auricularia auricula melanin (AAM) can alleviate IDA, but the mechanism is not clear.
WANG Yuting, LI Yuanjing, CHU Fuying, SHI Shuliang, LEI Hong, FENG Lei
doaj   +1 more source

Tryptophan metabolism in bipolar disorder

open access: yesEuropean Psychiatry, 2022
Introduction Immune mediated inflammatory processes are involved in the aetiopathogenesis of bipolar disorder (BD) and weight associated comorbidities. Tryptophan breakdown via indoleamine 2,3-dioxygenase-1 (IDO-1) along the kynurenine axis concomitant ...
F. Fellendorf   +11 more
doaj   +1 more source

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