Results 11 to 20 of about 119,637 (295)
TrpNet: Understanding Tryptophan Metabolism across Gut Microbiome [PDF]
Metabolites, 2021 Crosstalk between the gut microbiome and the host plays an important role in animal development and health. Small compounds are key mediators in this host–gut microbiome dialogue.
Yao Lu +5 more
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Tryptophan metabolism in depression [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 1970 Psychiatric patients suffering from endogenous depression and a control group without endogenous depression were given oral loads of L-tryptophan and urinary excretion determined of the tryptophan metabolites on the pyrrolase pathway: kynurenine, 3-hydroxykynurenine, and 3-hydroxyanthranilic acid.
G, Curzon, P K, Bridges
openaire +4 more sources
Toll-like Receptor Activation Remodels the Polyamine and Tryptophan Metabolism in Porcine Macrophages [PDF]
MetabolitesBackground: The early nutritional metabolism of piglets is intimately associated with the regulation of immune function, and amino acids play a crucial role in modulating the fate and function of porcine immune cells, especially macrophages. However, the
Meimei Zhang +3 more
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The Engagement of Cytochrome P450 Enzymes in Tryptophan Metabolism [PDF]
Metabolites, 2023 Tryptophan is metabolized along three main metabolic pathways, namely the kynurenine, serotonin and indole pathways. The majority of tryptophan is transformed via the kynurenine pathway, catalyzed by tryptophan-2,3-dioxygenase or indoleamine-2,3 ...
Anna Haduch +3 more
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Altered Tryptophan and Neopterin Metabolism In Cancer Patients [PDF]
Pteridines, 1998 Plasma 5-hydroxytryptamine (serotonin), tryptophan and neopterin levels were measured in patients with depressive cancer cachexia and in healthy controls during the same time period.
Iwagaki Hiromi +3 more
doaj +2 more sources
Tryptophan Metabolism and Gut-Brain Homeostasis [PDF]
, 2021 Tryptophan is an essential amino acid critical for protein synthesis in humans that has emerged as a key player in the microbiota-gut-brain axis. It is the only precursor for the neurotransmitter serotonin, which is vital for the processing of emotional ...
Kimia Zadeh +4 more
core +1 more source
Crosstalk between Tryptophan Metabolism via Kynurenine Pathway and Carbohydrate Metabolism in the Context of Cardio-Metabolic Risk—Review [PDF]
, 2021 Scientific interest in tryptophan metabolism via the kynurenine pathway (KP) has increased in the last decades. Describing its metabolites helped to increase their roles in many diseases and disturbances, many of a pro-inflammatory nature.
Małgorzata Kiluk +3 more
core +1 more source
A Defect in Tryptophan Metabolism [PDF]
Pediatric Research, 1976 Oral tryptophan loading tests were performed in a patient with photosensitive pellagra-like skin rash and cerebellar ataxia but without hyperaminoaciduria. Plasma tryptophan concentrations after loading were similar in the patient and control subjects.
P W, Wong +3 more
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Tryptophan Metabolism Is Associated with BMI and Adipose Tissue Mass and Linked to Metabolic Disease in Pediatric Obesity [PDF]
, 2022 The obesity epidemic has contributed to an escalating prevalence of metabolic diseases in children. Overnutrition leads to increased tryptophan uptake and availability.
Julia Lischka +5 more
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2023 BackgroundsGut microbiota plays a critical role in the onset and development of depression, but the underlying molecular mechanisms are unclear. This study was conducted to explore the relationships between gut microbiota and host’s metabolism in ...
Jing Xie +8 more
doaj +1 more source