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Tryptophan metabolism: Mechanism-oriented therapy for neurological and psychiatric disorders
Frontiers in Immunology, 2022 Neurological and psychiatric disorders are a category of chronic diseases that are widespread and pose serious mental and physical health problems for patients.
Dan Li +12 more
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Tryptophan research in panic disorder. [PDF]
, 2008 09.02.15 KB. Ok to add published version to spiral, OA paperA considerable body of evidence suggests the involvement of serotonin neurotransmission in the pathogenesis of panic disorder.
Shlik, J, Maron, E, Nutt, DJ
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A Defect in Tryptophan Metabolism [PDF]
Pediatric Research, 1976 Oral tryptophan loading tests were performed in a patient with photosensitive pellagra-like skin rash and cerebellar ataxia but without hyperaminoaciduria. Plasma tryptophan concentrations after loading were similar in the patient and control subjects.
P W, Wong +3 more
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Frontiers in Cellular and Infection Microbiology, 2023 BackgroundsGut microbiota plays a critical role in the onset and development of depression, but the underlying molecular mechanisms are unclear. This study was conducted to explore the relationships between gut microbiota and host’s metabolism in ...
Jing Xie +8 more
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Validation of a model of regulation in the tryptophan operon against multiple experiment data using global optimisation [PDF]
, 2009 This paper is concerned with validating a mathematical model of regulation in the tryptophan operon using global optimization. Although a number of models for this biochemical network are proposed, in many cases only qualitative agreement between the ...
Postlethwaite, I. +4 more
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Metabonomic Study of the Involvement of the Intestinal Microflora in the Improvement of Iron Deficiency Anemia (IDA) by Auricularia auricula Melanin in Mice [PDF]
Shipin Kexue, 2023 Iron deficiency anemia (IDA) is a common iron deficiency disease. IDA has become one of the major public health problems worldwide. Our previous studies have shown that Auricularia auricula melanin (AAM) can alleviate IDA, but the mechanism is not clear.
WANG Yuting, LI Yuanjing, CHU Fuying, SHI Shuliang, LEI Hong, FENG Lei
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Tryptophan Metabolism and Gut-Brain Homeostasis
, 2021 Tryptophan is an essential amino acid critical for protein synthesis in humans that has emerged as a key player in the microbiota-gut-brain axis. It is the only precursor for the neurotransmitter serotonin, which is vital for the processing of emotional ...
Kimia Zadeh +4 more
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Tryptophan metabolism in bipolar disorder
European Psychiatry, 2022 Introduction Immune mediated inflammatory processes are involved in the aetiopathogenesis of bipolar disorder (BD) and weight associated comorbidities. Tryptophan breakdown via indoleamine 2,3-dioxygenase-1 (IDO-1) along the kynurenine axis concomitant ...
F. Fellendorf +11 more
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, 2021 Scientific interest in tryptophan metabolism via the kynurenine pathway (KP) has increased in the last decades. Describing its metabolites helped to increase their roles in many diseases and disturbances, many of a pro-inflammatory nature.
Małgorzata Kiluk +3 more
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Tryptophan Metabolism in Alcoholism [PDF]
Nutrition Research Reviews, 1999 Studies of tryptophan (Trp) metabolism in relation to the serotonin status in alcoholism are of 2 types: (1) those related to the pharmacological effects of ethanol; (2) those concerning the serotonin status in the absence of alcohol intake. In experimental animals, acute and chronic ethanol administration and subsequent withdrawal exert a variety of ...
openaire +3 more sources