Results 21 to 30 of about 198,753 (295)
Microorganisms, 2021 Akkermansia muciniphila, a potential probiotic, has been proven to lessen the effects of several diseases. As established, the relative abundance of Akkermansia is positively correlated with tryptophan metabolism.
Jia Yin +7 more
doaj +1 more source
Metabolic and Stress Responses in Senegalese Soles (Solea senegalensis Kaup) Fed Tryptophan Supplements: E ects of Concentration and Feeding Period [PDF]
, 2019 The objective of this study was to assess the impact of di erent dietary Trp concentrations on the stress and metabolism response of juvenile Senegalese soles (Solea senegalensis). Fish (38.1 1.9 g) were fed di erent Trp-enriched feeds (0%, 1% and 2%
Giráldez, Inmaculada +6 more
core +4 more sources
Biomolecules, 2022 Emerging evidence suggests that neuroinflammation is involved in both depression and neurodegenerative diseases. The kynurenine pathway, generating metabolites which may play a role in pathogenesis, is one of several competing pathways of tryptophan ...
Knut Hestad +3 more
doaj +1 more source
Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer. [PDF]
, 2016 Renal cell carcinoma (RCC) is increasing in incidence, and a complete cure remains elusive. While immune-checkpoint antibodies are promising, interferon-based immunotherapy has been disappointing.
Abu Aboud, Omran +13 more
core +2 more sources
Urinary N-methylnicotinamide and β-aminoisobutyric acid predict catch-up growth in undernourished Brazilian children [PDF]
, 2015 Enteric infections, enteropathy and undernutrition in early childhood are preventable risk factors for child deaths, impaired neurodevelopment, and later life metabolic diseases.
Guerrant, RL +10 more
core +1 more source
Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]
, 2020 Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana +2 more
core +2 more sources
Tryptophan metabolism in depression [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 1970 Psychiatric patients suffering from endogenous depression and a control group without endogenous depression were given oral loads of L-tryptophan and urinary excretion determined of the tryptophan metabolites on the pyrrolase pathway: kynurenine, 3-hydroxykynurenine, and 3-hydroxyanthranilic acid.
G, Curzon, P K, Bridges
openaire +2 more sources
Frontiers in Pharmacology, 2023 Introduction: The 5-year survival of gastric cancer (GC) patients with advanced stage remains poor. Some evidence has indicated that tryptophan metabolism may induce cancer progression through immunosuppressive responses and promote the malignancy of ...
Peng Luo +6 more
doaj +1 more source
Tryptophan metabolites in depression: Modulation by gut microbiota
Frontiers in Behavioral Neuroscience, 2022 Clinical depression is a multifactorial disorder and one of the leading causes of disability worldwide. The alterations in tryptophan metabolism such as changes in the levels of serotonin, kynurenine, and kynurenine acid have been implicated in the ...
Iva Lukić +3 more
doaj +1 more source
Translating Metabolic Reprogramming into New Targets for Kidney Cancer. [PDF]
, 2017 In the age of bioinformatics and with the advent of high-powered computation over the past decade or so the landscape of biomedical research has become radically altered.
Abu Aboud, Omran, Weiss, Robert H
core +1 more source