Results 21 to 30 of about 10,379 (248)
Biomolecules, 2022 Emerging evidence suggests that neuroinflammation is involved in both depression and neurodegenerative diseases. The kynurenine pathway, generating metabolites which may play a role in pathogenesis, is one of several competing pathways of tryptophan ...
Knut Hestad +3 more
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, 2022 The obesity epidemic has contributed to an escalating prevalence of metabolic diseases in children. Overnutrition leads to increased tryptophan uptake and availability.
Julia Lischka +5 more
core +1 more source
Microorganisms, 2021 Akkermansia muciniphila, a potential probiotic, has been proven to lessen the effects of several diseases. As established, the relative abundance of Akkermansia is positively correlated with tryptophan metabolism.
Jia Yin +7 more
doaj +1 more source
Frontiers in Pharmacology, 2023 Introduction: The 5-year survival of gastric cancer (GC) patients with advanced stage remains poor. Some evidence has indicated that tryptophan metabolism may induce cancer progression through immunosuppressive responses and promote the malignancy of ...
Peng Luo +6 more
doaj +1 more source
, 2022 The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing and therefore is its burden of disease as NALFD is a risk factor for cirrhosis and is associated with other metabolic conditions such as type II diabetes, obesity, dyslipidaemia ...
Max Nieuwdorp +5 more
core +1 more source
Tryptophan metabolites in depression: Modulation by gut microbiota
Frontiers in Behavioral Neuroscience, 2022 Clinical depression is a multifactorial disorder and one of the leading causes of disability worldwide. The alterations in tryptophan metabolism such as changes in the levels of serotonin, kynurenine, and kynurenine acid have been implicated in the ...
Iva Lukić +3 more
doaj +1 more source
, 2023 (1) Background: L-tryptophan is a substrate for the synthesis of many biological compounds through the serotonin and kynurenine pathways. These compounds have a significant influence on gastrointestinal functions and mental processes.
Cezary Chojnacki +5 more
core +1 more source
SARS-CoV2 Infection Alters Tryptophan Catabolism and Phospholipid Metabolism
, 2021 Coronavirus disease 2019 (COVID-19) has so far infected hundreds of million individuals, with several million deaths worldwide. The lack of understanding of the disease pathophysiology and the host’s immune response has resulted in this rapid spread of ...
Xiangming Ji +2 more
core +1 more source
Association between Tryptophan Metabolism and Inflammatory Biomarkers in Dairy Cows with Ketosis
, 2023 Dairy cows with ketosis have high circulating beta-hydroxybutyric acid (BHBA) concentrations alongside which inflammation is concomitantly developed.
Xueping Yao +10 more
core +1 more source
Disturbed amino acid metabolism in HIV: association with neuropsychiatric symptoms
Frontiers in Psychiatry, 2015 Blood levels of the amino acid phenylalanine, as well as of the tryptophan breakdown product kynurenine, are found to be elevated in human immunodeficiency virus type 1 (HIV-1)-infected patients.
Johanna M Gostner +3 more
doaj +1 more source