Results 31 to 40 of about 198,753 (295)

A study of the effects of exercise on the urinary metabolome using normalisation to individual metabolic output [PDF]

, 2015
Aerobic exercise, in spite of its multi-organ benefit and potent effect on the metabolome, has yet to be investigated comprehensively via an untargeted metabolomics technology.
Anthony, Nahoum, Blackburn, Gavin, Daskalaki, Evangelia, Kalna, Gabriela, Watson, David, Zhang, Tong   +5 more
core   +5 more sources

Obesity and cancer: existing and new hypotheses for a causal connection [PDF]

, 2018
Existing explanations of obesity-associated cancer emphasise direct mutagenic effects of dietary components or hormonal imbalance. Some of these hypotheses are reviewed briefly, but recent evidence suggests a major role for chronic inflammation in cancer
Darlington, L. Gail, McPherson, Megan, Stone, Trevor W.   +2 more
core   +2 more sources

The kynurenine pathway as a therapeutic target in cognitive and neurodegenerative disorders [PDF]

, 2013
Understanding the neurochemical basis for cognitive function is one of the major goals of neuroscience, with a potential impact on the diagnosis, prevention and treatment of a range of psychiatric and neurological disorders.
Akagbosu, Akladios, Alexander, Alkondon, Alkondon, Alkondon, Amori, Andersen, Atlas, Autier, Backman, Beal, Benatti, Bonda, Breese, Carpenedo, Carpenedo, Casazza, Castellano, Ceresoli-Borroni, Cesura, Chess, Chess, Chess, Chiarugi, Chiarugi, Clark, Cochran, Cozzi, Cui, Daily, Dalley, Dantzer, Darlington, Darlington, Davidson, Deiana, Della Torre, DiNatale, Dobelis, Dounay, Eastman, Erhardt, Forrest, Forrest, Forrest, Forrest, Fukui, Gellert, Giordani, Giorgini, Gold, Graef, Guidetti, Guidetti, Guidetti, Guidetti, Guillemin, Guillemin, Hardingham, Hedges, Henderson, Heng, Hernandez, Heyes, Hilmas, Holtze, Jason, Jauch, Jentsch, Jurgens, Kalisch, Kandanearatchi, Kiank, Kihara, Kloet, Kocki, Konradsson-Geuken, Lawrence, Lawrence, Linderholm, Lindsley, Luchowski, Luchowski, Lupien, Marin, Mexal, Millan, Miller, Minzenberg, Miura, Moeller, Mok, Muchowski, Muchowski, Mueller, Muscatell, Myint, Nagy, Neill, Newcomer, Newcomer, Nilsson, Nilsson, Nozaki, O'Connor, Olsson, Onur, Owe-Young, Paterson, Pearson, Pechtel, Pellicciari, Pellicciari, Perkins, Pertovaara, Pevarello, Phillips, Pocivavsek, Pocivavsek, Popoli, Popoli, Potter, Rahman, Raison, Rassoulpour, Ren, Robert, Rodgers, Rossi, Ryu, Röver, Saito, Salazar, Sapko, Sarter, Sathyasaikumar, Sathyasaikumar, Schwarcz, Schwarcz, Schwarcz, Schwarcz, Shear, Speciale, Speciale, Stazka, Stazka, Stone, Stone, Stone, Stone, Stone, Stoy, Tadaiesky, Tatter, Teichberg, Teichberg, Ting, Trecartin, Tse, Varasi, Vezzani, Walker, Wang, Wang, Wejksza, Wejksza, Wonodi, Xu, Yamada, Yuen, Zisapel, Zmarowski   +172 more
core   +1 more source

2014 REU Poster: Measuring Tryptophan Metabolism Using Analogs of Tryptophan [PDF]

, 2014
Poster presentation at REU Summer's End Research Symposium, 2014, by REU participant Thierno Diallo, Roxbury Community College - John "Chip" Celenza group, Sanda Zolj lab mentorNSF ...
Diallo, Thierno
core   +4 more sources

The Use of Dietary Additives in Fish Stress Mitigation: Comparative Endocrine and Physiological Responses [PDF]

, 2019
In the last years, studies on stress attenuation in fish have progressively grown. This is mainly due to the interest of institutions, producers, aquarists and consumers in improving the welfare of farmed fish.
Abdel-Tawwab, Alderman, Alves Martins, Alves Martins, Alves Martins, Aragão, Araújo, Azeredo, Azeredo, Babaei, Baltzegar, Basic, Basic, Belo, Benítez-Dorta, Berntssen, Berntssen, Betancor, Blazer, Brake, Bransden, Cabanillas-Gámez, Cardoso, Chen, Chen, Chen, Cheng, Conceição, Conde-Sieira, Cosgrove, Costas, Costas, Costas, Costas, Costas, Costas, Dabrowska, Dabrowski, Davis, Dhabhar, Dimitroglou, Doyon, Eissa, Fabbri, Falahatkar, Faught, Fletcher, Forsatkar, Fracalossi, Fu, Fuchs, Ganga, Ganga, Ganga, Gil, González-Silvera, Gorissen, Gorissen, Gorissen, Gorissen, Grimble, Grimble, Guimarães, Habte-Tsion, Halver, Harpaz, Herrera, Hog¨lund, Hooley, Hoseini, Hoseini, Hoseinifar, Hseu, Hwang, Höglund, Höglund, Imanpoor, Iwama, Izquierdo, Jia, Kanazawa, Kenari, Khassaf, Kiilerich, Kim, Kim, Kiron, Kitabchi, Koshio, Koven, Kumar, Kumar, Küçükbay, Lall, Lanes, Leonardi, Leong, Lepage, Lepage, Lepage, Li, Li, Li, Li, Liu, Liu, Liu, Liu, Lochmann, Long, Martin, Martins, Martins, McDowell, McKenzie, McKenzie, Mechlaoui, Melnyk-Lamont, Miao, Mommsen, Montero, Montero, Montero, Montero, Montero, Morandini, Morrow, Naderi, Nye, Olmos-Soto, Palermo, Papoutsoglou, Pardue, Pérez-Jiménez, Pérez-Sánchez, Read, Rezek, Rider, Ringø, Rønnestad, Sakai, Saleh, Sang, Schreck, Schreck, Skrzynska, Solano, Sándor, Tahmasebi-Kohyani, Tejpal, Thompson, Tian, Tocher, Torrecillas, Torrecillas, Trenzado, Trenzado, Trushenski, Van Anholt, Van Anholt, Verburg-van Kemenade, Vijayan, Wang, Watanabe, Weirich, Winberg, Wolkers, Wu, Xie, Xu, Yao, Yoshizawa, Yousefi, Zacharieva   +173 more
core   +2 more sources

Disturbed amino acid metabolism in HIV: association with neuropsychiatric symptoms

Frontiers in Psychiatry, 2015
Blood levels of the amino acid phenylalanine, as well as of the tryptophan breakdown product kynurenine, are found to be elevated in human immunodeficiency virus type 1 (HIV-1)-infected patients.
Johanna M Gostner, Kathrin eBecker, Katharina eKurz, Dietmar eFuchs   +3 more
doaj   +1 more source

Quinolinate promotes macrophage-induced immune tolerance in glioblastoma through the NMDAR/PPARγ signaling axis

Nature Communications, 2023
The upstream metabolism of tryptophan has been described as a metabolic node in glioblastoma. Here the authors show that the downstream metabolism of tryptophan, resulting in the accumulation of quinolinate in glioblastoma, contributes to pro-tumorigenic
Pravin Kesarwani, Shiva Kant, Yi Zhao, Antony Prabhu, Katie L. Buelow, C. Ryan Miller, Prakash Chinnaiyan   +6 more
doaj   +1 more source

Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor [PDF]

, 2010
Background The transition from exponential to stationary phase in Streptomyces coelicolor is accompanied by a major metabolic switch and results in a strong activation of secondary metabolism.
Alam, Mohammad T., Breitling, Rainer, HASH(0x55aa09327868), Hodgson, D. A., Merlo, Maria E., Takano, Eriko, Wellington, E. M. H.   +6 more
core   +10 more sources

Generation of superoxide and singlet oxygen from α-tocopherolquinone and analogues. [PDF]

, 2007
Three potential routes to generation of reactive oxygen species from a tocopherolquinone have been identified. The quinone of the water-soluble vitamin E analogue Trolox C (Trol-Q) is reduced by hydrated electron and isopropanol a hydroxyalkyl radical ...
Bisby, RH, Crisostomo, AG, Moreno, RB, Navaratnam, S, Wilkinson, JA   +4 more
core   +1 more source

Alterations in tryptophan metabolism and de novo NAD+ biosynthesis within the microbiota-gut-brain axis in chronic intestinal inflammation

Frontiers in Medicine
BackgroundInflammatory bowel disease is an incurable and idiopathic disease characterized by recurrent gastrointestinal tract inflammation. Tryptophan metabolism in mammalian cells and some gut microbes comprise intricate chemical networks facilitated by
Jeannie Devereaux, Ainsley M. Robinson, Ainsley M. Robinson, Ainsley M. Robinson, Rhian Stavely, Rhian Stavely, Majid Davidson, Narges Dargahi, Ramya Ephraim, Dimitros Kiatos, Vasso Apostolopoulos, Vasso Apostolopoulos, Vasso Apostolopoulos, Kulmira Nurgali, Kulmira Nurgali, Kulmira Nurgali   +15 more
doaj   +1 more source