Results 31 to 40 of about 1,087,731 (295)

Metabolism of tryptophan along the kynurenine pathway in alloxan diabetic rabbits

, 2002
In vivo study of the metabolism of tryptophan along the kynurenine pathway in alloxan diabetic ...
ALLEGRI, GRAZIELLA, Guglielmina Froldi, COSTA, CARLO VIRGILIO LUIGI, G. ALLEGRI, Eugenio Ragazzi, Delia Zaccarin, FROLDI, GUGLIELMINA, C.V.L. COSTA, BERTAZZO, ANTONELLA, Carlo V.L. Costa, D. ZACCARIN, ZACCARIN D, RAGAZZI, EUGENIO, Graziella Allegri, Antonella Bertazzo, A. BERTAZZO   +15 more
core   +1 more source

Immune regulation through tryptophan metabolism

Experimental and Molecular Medicine, 2023
Amino acids are fundamental units of molecular components that are essential for sustaining life; however, their metabolism is closely interconnected to the control systems of cell function.
Su-Kil Seo, Byungsuk Kwon
doaj   +1 more source

Low Levels of Serum Tryptophan Underlie Skeletal Muscle Atrophy

, 2020
Sarcopenia is a poor prognosis factor in some cancer patients, but little is known about the mechanisms by which malignant tumors cause skeletal muscle atrophy.
Makoto Shiraki, Kimihiro Yamaguchi, Taku Mizutani, Hisashi Tsurumi, Nobuhiko Nakamura, Nobuhiro Kanemura, Junichi Kitagawa, Yuto Kaneda, Takuro Matsumoto, Masahito Shimizu, Soranobu Ninomiya, Hiroshi Nakamura, Takeshi Hara   +12 more
core   +1 more source

Deciphering tryptophan metabolism in colorectal cancer through multi-omics analysis

Biochemistry and Biophysics Reports
Metabolic reprogramming is essential for colorectal cancer (CRC) progression, and recent studies have pointed to tryptophan metabolism as a crucial modulator of the tumor immune microenvironment.
Chengcheng Zhang, Zhijing Rao, Xiangyang Zhan, Jingru Qin, Lu Yang, Qianqian Yin, Junqing Ji, Xiaoxue Zhao, Yiyi Liu, Zhanhui Lu, Guoying Wang, Xingshuai Huang, Wenbo Shi, Wan Su, Zhongqi Wang   +14 more
doaj   +1 more source

tryptophan metabolism-html

, 2014
unigenes related to tryptophan ...
Karen Fugate (480954)
core   +1 more source

Quinolinate promotes macrophage-induced immune tolerance in glioblastoma through the NMDAR/PPARγ signaling axis

Nature Communications, 2023
The upstream metabolism of tryptophan has been described as a metabolic node in glioblastoma. Here the authors show that the downstream metabolism of tryptophan, resulting in the accumulation of quinolinate in glioblastoma, contributes to pro-tumorigenic
Pravin Kesarwani, Shiva Kant, Yi Zhao, Antony Prabhu, Katie L. Buelow, C. Ryan Miller, Prakash Chinnaiyan   +6 more
doaj   +1 more source

tryptophan metabolism-png

, 2014
unigenes related to tryptophan ...
Karen Fugate (480954)
core   +1 more source

Alterations in tryptophan metabolism and de novo NAD+ biosynthesis within the microbiota-gut-brain axis in chronic intestinal inflammation

Frontiers in Medicine
BackgroundInflammatory bowel disease is an incurable and idiopathic disease characterized by recurrent gastrointestinal tract inflammation. Tryptophan metabolism in mammalian cells and some gut microbes comprise intricate chemical networks facilitated by
Jeannie Devereaux, Ainsley M. Robinson, Ainsley M. Robinson, Ainsley M. Robinson, Rhian Stavely, Rhian Stavely, Majid Davidson, Narges Dargahi, Ramya Ephraim, Dimitros Kiatos, Vasso Apostolopoulos, Vasso Apostolopoulos, Vasso Apostolopoulos, Kulmira Nurgali, Kulmira Nurgali, Kulmira Nurgali   +15 more
doaj   +1 more source

Tryptophan and indole metabolism in immune regulation

, 2021
L-tryptophan is an essential amino acid that undergoes complex metabolic routes, resulting in production of many types of signaling molecules that fall into two types: retaining the indole ring such as serotonin, melatonin and indolepyruvate or breaking ...
Fiore, A., Fiore A., Murray P. J., Murray, P., Alessandra Fiore, Peter J Murray   +5 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source