Effects of Dietary Pyrazinamide on the Metabolism of Tryptophan to Niacin in Streptozotocin-diabetic Rats [PDF]
Katsumi Shibata +2 more
openalex +1 more source
Hydrogen‐deuterium exchange mass spectrometry validated AlphaFold structural prediction of the class III biotin protein ligase (BPL) from Saccharomyces cerevisiae, and revealed a structured domain in the N‐terminal extension characteristic to this class of BPL.
Louise M. Sternicki +6 more
wiley +1 more source
Dihydrosanguinarine enhances tryptophan metabolism and intestinal immune function via AhR pathway activation in broilers. [PDF]
Su Y, Wang M, Wu Z, Huang P, Zeng J.
europepmc +1 more source
ThiF‐Like Enzyme Chemistry in Primary and Secondary Metabolism
ThiF‐like enzymes are a widespread protein family found in disparate biosynthetic pathways. They are unified by their use of an NTP to modify a carboxylate, generating an activated species prone to nucleophilic addition. This common intermediate is then targeted by diverse nucleophiles, including persulfide or amino acid side chains, to yield a variety
Keelie S. Butler +2 more
wiley +1 more source
Tryptophan metabolism and ischemic stroke: An intricate balance. [PDF]
Yao C +8 more
europepmc +1 more source
Influence of Adenine-induced Renal Failure on Tryptophan-niacin Metabolism in Rats [PDF]
Tsutomu Fukuwatari +4 more
openalex +1 more source
Reaction Engineering of In Vitro Natural Product Biosynthesis: Challenges and Strategies
The yield and turnover of in vitro natural product biosynthesis, and even its feasibility, are determined by intermolecular interactions. Reaction engineering allows to improve the performance of such complex biocatalytic systems. Natural products are widely used as pharmaceuticals and agrochemicals, or as active ingredients in food and cosmetics ...
Elsa Sánchez‐García +2 more
wiley +1 more source
Biocompatible Chemistry: A Plug‐and‐Play Toolbox for Chemical Biology Research
The “plug‐and‐play” nature of biocompatible chemistry makes it a powerful toolbox for investigating complicated biological systems and producing drug leads for clinical usages. This review summarizes the commonly used biocompatible reactions and the recent advances of their representative applications in chemical biology research, thus highlighting the
Adam R. Lovato, Zeng Lin, Qingfei Zheng
wiley +1 more source
Promising Gastric Cancer Biomarkers-Focus on Tryptophan Metabolism via the Kynurenine Pathway. [PDF]
Ożga K +3 more
europepmc +1 more source
Targeting Cryptochromes in Chronic Diseases
ABSTRACT The circadian clock generates 24‐h molecular rhythms through transcription–translation negative feedback loops (TTFLs) and regulates daily physiological processes such as sleep–wake cycles, body temperature, hormone secretion, metabolism, and immune function.
Takuro Toda, Tsuyoshi Hirota
wiley +1 more source

