Results 151 to 160 of about 70,579 (241)

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source

Molecular Insights Into the Interaction of Tryptophan Metabolites With Tryptophan and Indoleamine 2,3-Dioxygenases: Nitric Oxide a New Effector of Tryptophan 2,3-Dioxygenase and Their Roles in Infection. [PDF]

Int J Tryptophan Res
Badawy AA, Dawood S.
europepmc   +1 more source

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

Analysis of serum amino acids and tryptophan metabolites to predict hepatic encephalopathy in portal hypertension patients receiving a transjugular intrahepatic portal shunt (TIPS). [PDF]

Front Pharmacol
Bao L, Lv Y, Yang C, Li J, Liu F, Shi Z.
europepmc   +1 more source

Microbiota-derived tryptophan metabolites in vascular inflammation and cardiovascular disease. [PDF]

Amino Acids, 2022
Paeslack N, Mimmler M, Becker S, Gao Z, Khuu MP, Mann A, Malinarich F, Regen T, Reinhardt C.   +8 more
europepmc   +1 more source

The Genetic Link Between Primary Immune Thrombocytopenia and Depression/Anxiety Disorders: A Two‐Sample Mendelian Randomization Study

Journal of Clinical Laboratory Analysis, EarlyView.
A two‐sample Mendelian randomization study revealed a positive genetic association between primary immune thrombocytopenia (ITP) and major depressive disorder (MDD), but not with anxiety. Results remained consistent across sensitivity and multivariable analyses, indicating that ITP may causally increase susceptibility to depression.
Le Jiang, Ya‐jing Zhao, Shou‐qing Han, Zhen‐yu Yan, Xin‐guang Liu   +4 more
wiley   +1 more source

IBS May Have a Causal Effect on Increased Tryptophan Metabolites Levels: Insights from a Bidirectional Two-Sample Mendelian Randomization Study. [PDF]

Int J Tryptophan Res
Cheng P, Jia R, Jin B, Zhou F, Xu H, Wang B.   +5 more
europepmc   +1 more source

Optimization of light spectrum and intensity to enhance growth and metabolite profiles in green and purple radish microgreens cultivated in a vertical farming system

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Microgreens have emerged as a promising crop in vertical farming due to their high nutritional value and short growth cycles. Light spectrum and intensity are critical factors influencing biomass production and metabolic activity in plants, particularly in controlled environments such as vertical farming systems. This study aimed to
Cristian Hernández‐Adasme, Vicente Martínez, Mónica Flores, Teresa Mestre, Antonio Frutos‐Tortosa, Ulises Navarro‐Zapata, Alejandro Martínez‐Moreno   +6 more
wiley   +1 more source

Lactiplantibacillus plantarum attenuate gossypol-induced hepatic lipotoxicity by altering intestinal microbiota for enriching microbial tryptophan metabolites in Nile tilapia (Oreochromis niloticus). [PDF]

Microbiome
Ding FF, Zhou NN, Mao YJ, Yang J, Limbu SM, Galindo-Villegas J, Du ZY, Zhang ML.   +7 more
europepmc   +1 more source

Lactuca sativa L. losses and wastes as a source of biobased ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The growing global population and increasing consumer focus on healthy eating challenge the agricultural sector to ensure both sustainable food production and safety. Lettuce (Lactuca sativa Mill.), the most cultivated leafy vegetable worldwide, can lose up to 40% of its weight during processing.
Joana PB Rodrigues, Tayse FF da Silveira, Daniele B Rodrigues, Laura Domínguez, Patricia Morales, Tânia CSP Pires, Maria Beatriz PP Oliveira, Ângela Fernandes, Lillian Barros   +8 more
wiley   +1 more source