RNAi-induced silencing of embryonic tryptophan oxygenase in the Pyralid moth, Plodia interpunctella [PDF]
Gene silencing through the introduction of double-stranded RNA (RNA interference, RNAi) provides a powerful tool for the elucidation of gene function in many systems, including those where genomics and proteomics are incomplete.
Jeffrey A. Fabrick+2 more
doaj +4 more sources
Molecular cloning and analysis of the tryptophan oxygenase gene in the silkworm, Bombyx mori. [PDF]
Yan L+5 more
europepmc +3 more sources
Novel immune cell infiltration-related biomarkers in atherosclerosis diagnosis [PDF]
Background Immune cell infiltration (ICI) has a close relationship with the progression of atherosclerosis (AS). Therefore, the current study was aimed to explore the role of genes related to ICI and to investigate potential mechanisms in AS.
Ruoyu Dong+5 more
doaj +2 more sources
Detoxification of Indole by an Indole-Induced Flavoprotein Oxygenase from Acinetobacter baumannii. [PDF]
Indole, a derivative of the amino acid tryptophan, is a toxic signaling molecule, which can inhibit bacterial growth. To overcome indole-induced toxicity, many bacteria have developed enzymatic defense systems to convert indole to non-toxic, water ...
Guang-Huey Lin+2 more
doaj +1 more source
Tuberculosis (TB) caused by the complex Mycobacterium tuberculosis (Mtb) is the main cause of death by a single bacterial agent. Last year, TB was the second leading infectious killer after SARS-CoV-2.
Vasti Lozano-Ordaz+7 more
doaj +1 more source
HEME OXYGENASE-1 UPREGULATED BY MELATONIN: POTENTIAL PROTECTION AGAINST BURN-INDUCED OXIDATIVE GASTRIC MUCOSAL INJURY. [PDF]
Melatonin is indoleamine hormone derived from L-tryptophan. Due to its lipophilic nature, it is accessible to every cell. Melatonin has immunomodulatory and antioxidant activities thus protecting tissue injury.
Minka Hristova+2 more
doaj +1 more source
Ultraviolet Nanophotonics Enables Autofluorescence Correlation Spectroscopy on Label-Free Proteins With a Single Tryptophan [PDF]
Using the ultraviolet autofluorescence of tryptophan aminoacids offers fascinating perspectives to study single proteins without the drawbacks of fluorescence labelling. However, the low autofluorescence signals have so far limited the UV detection to large proteins containing several tens of tryptophan residues.
arxiv +1 more source
Ultraviolet superradiance from mega-networks of tryptophan in biological architectures [PDF]
Networks of tryptophan -- an aromatic amino acid with strong fluorescent response -- are ubiquitous in biological systems, forming diverse architectures in transmembrane proteins, cytoskeletal filaments, sub-neuronal elements, photoreceptor complexes, virion capsids, and other cellular structures.
arxiv +1 more source
Tryptophan metabolism in tsetse flies and the consequences of its derangement
Literature comparing salmon and wild type Glossina morsitans morsitans and that comparing tan and wild type Glossina palpalis palpalis is reviewed. New information is presented on behaviour and biochemistry of salmon and wild type G. m. morsitans.
R. H. Gooding, B. M. Rolseth
doaj +1 more source
Background The kynurenine pathway (KP) is the main route of tryptophan degradation in the human body and generates several neuroactive and immunomodulatory metabolites.
Kegel Magdalena+9 more
doaj +1 more source