Results 21 to 30 of about 7,892 (182)

Novel immune cell infiltration-related biomarkers in atherosclerosis diagnosis [PDF]

open access: yesPeerJ, 2023
Background Immune cell infiltration (ICI) has a close relationship with the progression of atherosclerosis (AS). Therefore, the current study was aimed to explore the role of genes related to ICI and to investigate potential mechanisms in AS.
Ruoyu Dong   +5 more
doaj   +2 more sources

Tryptophan, Oxygenase, and Sleep

open access: yes, 1996
In May 1974, or about 21 years ago, when the first International Meeting of ISTRY was held in this beautiful city of Padova, I had the great pleasure of making personal acquaintance with Prof. Luigi Musajo, whom I had heard about so much while I was in Japan.
O. Hayaishi
core   +2 more sources

Beneficial or detrimental activity of regulatory T cells, indoleamine 2,3-dioxygenase, and heme oxygenase-1 in the lungs is influenced by the level of virulence of Mycobacterium tuberculosis strain infection

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Tuberculosis (TB) caused by the complex Mycobacterium tuberculosis (Mtb) is the main cause of death by a single bacterial agent. Last year, TB was the second leading infectious killer after SARS-CoV-2.
Vasti Lozano-Ordaz   +7 more
doaj   +1 more source

The Prematurely Evoked Synthesis of Liver Tryptophan Oxygenase [PDF]

open access: yesProceedings of the National Academy of Sciences, 1971
Livers of normal rats are devoid of catalytically or immunochemically reactive tryptophan oxygenase (EC 1.13.1.12) up to the 10th postnatal day; the enzyme reaches adult concentrations on about the twentieth day. Premature tryptophan oxygenase synthesis can be evoked in 4-day-old rats: if an injection of glucocorticoid is followed, a day later, by an ...
O, Greengard, H K, Dewey
openaire   +2 more sources

Effects of pro-inflammatory cytokines on expression of kynurenine pathway enzymes in human dermal fibroblasts

open access: yesJournal of Inflammation, 2011
Background The kynurenine pathway (KP) is the main route of tryptophan degradation in the human body and generates several neuroactive and immunomodulatory metabolites.
Kegel Magdalena   +9 more
doaj   +1 more source

Heme Metabolism-Derived Carbon Monoxide Regulates Skeletal Muscle Function. [PDF]

open access: yesJ Cachexia Sarcopenia Muscle
ABSTRACT Background Heme oxygenases, HO‐1 (Hmox1) and HO‐2 (Hmox2), regulate skeletal muscle homeostasis by degrading heme and generating carbon monoxide (CO), a bioactive signalling molecule. Although HO‐1 is known to influence muscle fibre composition and mitochondrial function, the role of HO‐2 in activity‐dependent neuromuscular plasticity remains ...
Alves de Souza RW   +8 more
europepmc   +2 more sources

The Tryptophan oxygenase gene of Anopheles gambiae

open access: yesInsect Biochemistry and Molecular Biology, 1996
The Anopheles gambiae gene encoding tryptophan oxygenase, a homolog of the Drosophila melanogaster vermilion gene, has been molecularly cloned and characterized. Unlike Drosophila, where it is X-linked, the A. gambiae gene maps to chromosome 2R, subdivision 12E, by in situ hybridization to the polytene chromosomes.
A.J. Cornel   +4 more
core   +3 more sources

Key Enzymes and Proteins of Crop Insects as Candidate for RNAi Based Gene Silencing

open access: yesFrontiers in Physiology, 2015
RNA interference (RNAi) is a mechanism of homology dependent gene silencing present in plants and animals. It operates through 21-24 nucleotides small RNAs which are processed through a set of core enzymatic machinery that involves Dicer and Argonaute ...
Vijaya Sudhakara Rao K   +3 more
doaj   +1 more source

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