Results 31 to 40 of about 87,880 (172)

Serotonin and social norms : tryptophan depletion impairs social comparison and leads to resource depletion in a multiplayer harvesting game [PDF]

open access: yes, 2014
How do people sustain resources for the benefit of individuals and communities and avoid the tragedy of the commons, in which shared resources become exhausted?
Rogers, Robert D.   +23 more
core   +1 more source

Purification and Properties of Rat Liver Tryptophan Oxygenase

open access: yesJournal of Biological Chemistry, 1972
Abstract Tryptophan oxygenase has been purified from livers of glucocorticoid and l-tryptophan-treated rats. Homogeneity of the enzyme was established by polyacrylamide electrophoresis, sedimentation experiments, and immunodiffusion. Amino acid analyses reveal 6 residues of cysteine per enzyme molecule.
G, Schutz, P, Feigelson
openaire   +2 more sources

NMDA receptor activation mediates lipopolysaccharide-induced depressive-like behavior

open access: yesEuropean Journal of Psychotraumatology, 2012
Background : Inflammation associated with cancer and induced by cancer therapy is associated with clinical signs of sickness behavior that can culminate in the development of symptoms of depression. Intraperitoneal administration of lipopolysaccharide to
Adam Walker   +4 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Tryptophan depletion increases nausea, headache and photophobia in migraine sufferers [PDF]

open access: yes, 2006
Sensitivity to light was investigated 5 and 8 h after consumption of an amino acid drink which contained L-tryptophan (balanced amino acid condition: 19 controls and 22 migraine sufferers) or which produced a short-term reduction in brain serotonin ...
Drummond, P.D.
core  

The Tryptophan and Kynurenine Pathway Involved in the Development of Immune-Related Diseases

open access: yes, 2023
The tryptophan and kynurenine pathway is well-known to play an important role in nervous, endocrine, and immune systems, as well as in the development of inflammatory diseases.
Asai Tomoko   +13 more
core   +1 more source

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

open access: yesFood Biomacromolecules, EarlyView.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source

Regulation of haem oxygenase-1 nitrosative stress in cardiac cells. [PDF]

open access: yes, 2005
The reactive nitrogen species (RNS) nitric oxide (NO), nitroxyl anion (NO") and nitrosonium cation (NO+), modulate a myriad of biological processes. The microsomal haem oxygenases (HO-1, HO-2 and HO-3) oxidatively catabolise haem to bilirubin, carbon ...
Naughton, P.
core  

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen   +2 more
wiley   +1 more source

GCN2 in proteostasis: structural logic, signalling networks and disease

open access: yesThe FEBS Journal, EarlyView.
Threats to protein synthesis activate the kinase GCN2, initiating the integrated stress response (ISR). GCN2 is triggered by stalled ribosomes and uncharged tRNAs, which accumulate when amino acids are scarce. The ISR adjusts cellular physiology by promoting redox balance, protein quality control, and mitochondrial optimisation.
JiaYi Zhu, Stefan J. Marciniak
wiley   +1 more source

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