BMC Microbiology, 2010 Background Acidithiobacillus ferrooxidans is chemolithoautotrophic γ-proteobacterium that thrives at extremely low pH (pH 1-2). Although a substantial amount of information is available regarding CO2 uptake and fixation in a variety of facultative ...
Esparza Mario +4 more
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Metabolic and molecular events occurring during chromoplast biogenesis [PDF]
, 2011 Chromoplasts are nonphotosynthetic plastids that accumulate carotenoids. They derive from other plastid forms, mostly chloroplasts. The biochemical events responsible for the interconversion of one plastid form into another are poorly documented. However,
Barsan, Cristina +8 more
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Sirtuin 2 regulates neutrophil functions through NAD+ synthesis pathway in virus infection
iScienceSummary: Neutrophils play an important role in antiviral immunity, but the underlying mechanisms remain unclear. Here, we found that SIRT2 deficiency inhibited the infiltration of neutrophils, as well as the secretion of inflammatory cytokines and the ...
Zhiyuan Zhang +7 more
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THE CONCISE GUIDE TO PHARMACOLOGY 2017/18:Enzymes [PDF]
, 2017 The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and ...
, +11 more
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The N-end rule pathway is a sensor of heme [PDF]
, 2008 The conjugation of arginine, by arginyl-transferase, to N-terminal aspartate, glutamate or oxidized cysteine is a part of the N-end rule pathway of protein degradation.
A. Varshavsky +21 more
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Purification and Properties of Rat Liver Tryptophan Oxygenase
Journal of Biological Chemistry, 1972 Abstract Tryptophan oxygenase has been purified from livers of glucocorticoid and l-tryptophan-treated rats. Homogeneity of the enzyme was established by polyacrylamide electrophoresis, sedimentation experiments, and immunodiffusion. Amino acid analyses reveal 6 residues of cysteine per enzyme molecule.
G, Schutz, P, Feigelson
openaire +2 more sources
Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis [PDF]
, 2009 Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasites <i>Trypanosoma brucei rhodesiense</i> or <i>Trypanosoma brucei gambiense</i>, and is a major cause of systemic and neurological disability ...
Adams +37 more
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Regulatory T cell-mediated anti-inflammatory effects promote successful tissue repair in both indirect and direct manners [PDF]
, 2015 Regulatory T cells (Tregs) offer new immunotherapeutic options to control undesired immune reactions, such as those in transplant rejection and autoimmunity.
Dienelt, Anke +4 more
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NMDA receptor activation mediates lipopolysaccharide-induced depressive-like behavior
European Journal of Psychotraumatology, 2012 Background : Inflammation associated with cancer and induced by cancer therapy is associated with clinical signs of sickness behavior that can culminate in the development of symptoms of depression. Intraperitoneal administration of lipopolysaccharide to
Adam Walker +4 more
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Immunomodulatory properties of mesenchymal stem cells: Cytokines and factors
, 2012 Mesenchymal stem cells (MSCs) are defined as undifferentiated cells that are capable of self renewal and differentiation into several cell types such as chondrocyte, adipocyte, osteocyte, myocyte, hepatocyte, and neuron-like cells.
Pramanik, K. +2 more
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