Results 121 to 130 of about 16,704 (236)
Allergy, Volume 81, Issue 9, Page 3345-3360, September 2026.Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton +19 more
wiley +1 more source
Allergy, Volume 81, Issue 9, Page 3107-3129, September 2026.ABSTRACT Advances in asthma therapies have shown that clinical remission may be an achievable therapeutic goal for patients with asthma. This review discusses the current definitions of remission in asthma, the predictors of remission, airway inflammation/epithelial damage in asthma remission, airway remodeling, paradigms in defining remission and ...
Fatma Esra Gunaydin +4 more
wiley +1 more source
Insight into the role of TSLP in inflammatory bowel diseases
, 2017 Proinflammatory cytokines are thought to modulate pathogeneses of various inflammatory bowel diseases (IBDs). Thymic stromal lymphopoietin (TSLP), which has been studied in various allergic diseases such as asthma, atopic dermatitis (AD) and eosinophilic
신재일
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Effect of Dupilumab on Airway Inflammation in Patients With Persistent Asthma
Allergy, Volume 81, Issue 9, Page 3261-3272, September 2026.EXPEDITION (NCT02573233) assessed the effects of dupilumab on airway inflammation in patients with persistent asthma using bronchoscopy and gene expression analysis. Dupilumab showed no appreciable effect on inflammatory cell types in biopsies or BALF samples.
Michael E. Wechsler +22 more
wiley +1 more source
, 2021 ilustraciones, graficasIntroducción: El asma es una enfermedad heterogénea, caracterizada por inflamación crónica de la vía aérea, con síntomas respiratorios variables relacionados con limitación al flujo aérea.
Ramírez Camacho, Oscar Javier
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Remission in Global Airway Diseases: EUFOREA Consensus Paper
Allergy, Volume 81, Issue 9, Page 3146-3156, September 2026.ABSTRACT The therapeutic goal in chronic airway diseases is shifting from symptom control to disease remission. Disease‐modifying therapies, including biologics and allergen immunotherapy, have made remission achievable in patients with severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), or allergic rhinitis (AR).
J. Christian Virchow +22 more
wiley +1 more source
LINFOPOYETINA ESTROMAL TÍMICA: REGULACIÓN DE LA RESPUESTA INMUNE Y LA ENFERMEDAD ALÉRGICA
Universitas Scientiarum, 2007 Recientemente se ha descrito una citocina similar a interleucina (IL) 7: Thymic Stromal Lymphopoietin (TSLP). La molécula TSLP es secretada por células epiteliales y en humanos estimula principalmente células de linaje mieloide, a diferencia del ratón ...
A. Cuéllar
doaj
The Airway Transcriptome in Type 2 Cytokine Biomarker‐High and ‐Low Severe Asthma
Allergy, Volume 81, Issue 9, Page 3300-3317, September 2026.This study distinguishes severe asthma–related airway transcriptomic changes from the effects of high‐dose ICS. Most dysregulated genes in severe asthma show concordance with corticosteroid responses. Corticosteroid‐resistant T2‐high asthma featured T2‐high and epithelial barrier gene upregulation, while T2‐low asthma featured Th1/IL‐17 signatures. ASM,
Jiashu Shen +19 more
wiley +1 more source
Characterizing thymic stromal lymphopoietin (TSLP): a role in neurite outgrowth
, 2014 Neuropathy is a serious complication of diabetes mellitus. In particular, sensory innervation is progressively lost as neurons degenerate distally. Many proinflammatory cytokines have been implicated in signalling through pathways that mediate nerve ...
Verrelli, Alyssa
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