Results 111 to 120 of about 17,739 (188)

The Role of Mitochondrial Homeostasis in the Pathogenesis of Chronic Rhinosinusitis

Immunity, Inflammation and Disease, Volume 14, Issue 11, November 2026.
The vicious cycle between pathogenic factors‐induced inflammation, oxidative stress, and mitochondrial dysfunction in the context of chronic rhinosinusitis. Created in BioRender. Taghizadeh‐Hesary (2026) https://BioRender.com/k5f4t1f. ABSTRACT Background Chronic rhinosinusitis (CRS) is a common clinical condition characterized by persistent ...
Babak Ghalehbaghi, Morteza Fallahpour, Mohammad Nabavi, Maryam Jalessi, Hadi Ghanbari, Nasibeh Khayer, Farzad Taghizadeh‐Hesary   +6 more
wiley   +1 more source

Adaptive Immunity in Marsupials

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 9, Page 913-932, November 2026.
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol, Hayley J. Stannard, Julie M. Old   +2 more
wiley   +1 more source

Inhaled Nanomedicines for Lung Diseases and Injuries: Pharmacological Advances and Clinical Translation

MedComm, Volume 7, Issue 11, November 2026.
Graphical overview of bioinspired regenerative platforms designed to remodel the diseased lung microenvironment. These systems integrate gene addition, siRNA‐mediated transcript silencing, CRISPR‐based modulation, and base editing approaches to promote alveolar repair, AT2‐to‐AT1 regeneration, resolution of inflammation, and restoration of vascular ...
Kajal Kamra, Sonal Gaur, Jaswinder Singh
wiley   +1 more source

Asthma: From Phenotypes to Endotypes—Beyond Type 2 Inflammation

Respirology, Volume 31, Issue 11, Page 1077-1090, November 2026.
ABSTRACT Asthma is a heterogeneous syndrome featuring variable pathophysiology, clinical presentation and treatment response. This review examines a comprehensive endotype‐phenotype framework for asthma assessment with an emphasis on characteristics beyond T2 inflammatory status alone.
Mario Fernando, Gregory G. King
wiley   +1 more source

Characterizing thymic stromal lymphopoietin (TSLP): a role in neurite outgrowth [PDF]

, 2014
Neuropathy is a serious complication of diabetes mellitus. In particular, sensory innervation is progressively lost as neurons degenerate distally. Many proinflammatory cytokines have been implicated in signalling through pathways that mediate nerve ...
Verrelli, Alyssa
core  

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, Volume 81, Issue 11, Page 3825-3852, November 2026.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

Prolyl hydroxylase inhibition protects against murine MC903-induced skin inflammation by downregulating TSLP

Frontiers in Immunology
Previously, we reported an anti-inflammatory effect of mTORC1 in a mouse model of type 2 skin inflammation. TSLP, one of the epithelial cell-derived cytokines, was upregulated by Raptor deficiency or rapamycin treatment, which was inhibited by ...
Anupriya Gupta, Mi Hye Song, Dong Hyuk Youn, Dohyeon Ku, Varun Sasidharan Nair, Kwonik Oh, Kwonik Oh   +6 more
doaj   +1 more source

Extracellular Vesicles in Dermatology: Where Are We and What Lies Ahead?

Experimental Dermatology, Volume 35, Issue 11, November 2026.
ABSTRACT Extracellular vesicles (EVs) have emerged as key players in skin biology, mediating intercellular communication across diverse physiological and pathological contexts. In this review, we critically assess the current understanding of EVs in dermatology, highlighting their roles in skin homeostasis, ageing, inflammation, wound healing and ...
Ines Martic, Alessandro Paolini, Stefania Paola Bruno, Andrea Gallego, Dorottya Ádám, Sedat Odabas, Şebnem Erçelen Ceylan, Emanuela Camera, Paloma Pérez, Attila Oláh, Andrea Masotti, Mirjana Nacka‐Aleksić, Danuta Gutowska‐Owsiak, Nsrein Ali, Maria Cavinato   +14 more
wiley   +1 more source

Specificity evaluation of the TSLP and USLP.

, 2014
(A) PCR bands of miR-150 and miR-155 were detected by both TSLP and USLP methods. The PCR products were run on 3% agarose gel in 1X TBE stained with ethidium bromide. (B) Melting curve of the TSLP and USLP methods for detecting synthetic miR-155.
Si-lu Wang (680189), Li-hong Yang (680188), Li-li Tang (680190), Wen-le Ye (680191), Meng-tao Zhou (680194), Zhang-yang Wang (680193), Bi-cheng Chen (129208), Biao Liu (402867), Ling-ling Wang (680192)   +8 more
core   +1 more source

The Cytokine Response of Circulating Immune Cells to Rhinovirus (RV‐A16) is Reduced in Severe Asthma

Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Severe asthma patients (SA) are more susceptible to respiratory infections with human rhinoviruses (HRV) than healthy subjects (H), causing exacerbations. In response to HRV, circulating immune cells are recruited to and activated at the local sites of infection.
Kaschin Jamal Jameel, Sarah D. Yanik, Kai Robin Pfeifer, Daniel Weidinger, Simon Rohde, Birte Struck, Eike Bülthoff, Paul Bürger, Juliane Kronsbein, Matthias Tenbusch, Jürgen Knobloch   +10 more
wiley   +1 more source