TSST-1+Staphylococcus aureus in Bullous Pemphigoid. [PDF]
J Invest Dermatol, 2022 A potential role of S. aureus in BP was explored by examining the colonization rate in patients with new-onset disease, compared to age- and sex-matched controls. S. aureus colonization was observed in 85% of BP lesions; 3-6-fold higher than the nares or
Messingham KN +5 more
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Distribution of tsst-1 and mecA Genes in Staphylococcus aureus Isolated From Clinical Specimens. [PDF]
Jundishapur J Microbiol, 2016 Background Staphylococcus aureus is a harmful pathogen known to express numerous virulence factors and cause severe infections. High levels of methicillin-resistant Staphylococcus aureus (MRSA) strains are one of the important healthcare problems because
Zarei Koosha R +4 more
europepmc +5 more sources
Photoactivated Gallium Porphyrin Reduces <i>Staphylococcus aureus</i> Colonization on the Skin and Suppresses Its Ability to Produce Enterotoxin C and TSST-1. [PDF]
Mol Pharm, 2023 Staphylococcus aureus is a key pathogen in atopic dermatitis (AD) pathogenicity. Over half of AD patients are carriers of S. aureus. Clinical isolates derived from AD patients produce various staphylococcal enterotoxins, such as staphylococcal ...
Szymczak K +6 more
europepmc +2 more sources
An immunoinformatics approach for the design of a multi-epitope vaccine targeting super antigen TSST-1 of Staphylococcus aureus. [PDF]
J Genet Eng Biotechnol, 2021 TSST-1 is a secretory and pyrogenic superantigen that is being responsible for staphylococcal mediated food poisoning and associated clinical manifestations.
Kolla HB +3 more
europepmc +2 more sources
High Titer Persistent Neutralizing Antibodies Induced by TSST-1 Variant Vaccine Against Toxic Shock Cytokine Storm. [PDF]
Toxins (Basel), 2020 Staphylococcal superantigen toxins lead to a devastating cytokine storm resulting in shock and multi-organ failure. We have previously assessed the safety and immunogenicity of a recombinant toxic shock syndrome toxin 1 variant vaccine (rTSST-1v) in ...
Roetzer A +6 more
europepmc +2 more sources
Molecular Typing and Variations in Amount of tst Gene Expression of TSST-1-Producing Clinical Staphylococcus aureus Isolates. [PDF]
Front Microbiol, 2019 The toxic shock syndrome toxin-1 (TSST-1), encoded by tst gene, has been proposed to cause staphylococcal toxic shock syndrome (TSS) in a susceptible host, which highlights the need to evaluate the level of tst gene expression and molecular genetic ...
Zhao H +9 more
europepmc +2 more sources
018 TSST-1+ Staphylococcus aureus in bullous pemphigoid [PDF]
Journal of Investigative Dermatology, 2021 013 Different effects of combined blockade of IL-4/IL-13 and selective inhibition of IL-13 in in vitro model systems for atopic dermatitis with allergen stimulated lymphocytes T Honstein, S Evers, LM Roesner, J Zeitvogel and T Werfel Department of ...
K. Messingham +5 more
semanticscholar +2 more sources
β-(1→3)-D-glucan modulates DNA binding of nuclear factors κB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1β/IL-1 receptor antagonist ratio [PDF]
BMC Immunology, 2006 Background β-1→3-D-glucans represent a pathogen-associated molecular pattern and are able to modify biological responses. Employing a comprehensive methodological approach, the aim of our in vitro study was to elucidate novel molecular and cellular ...
Koritke Petra +10 more
doaj +5 more sources
Molecular Genotyping of Tsst-1 Gene Staphylococcus Aureus from Clinical Specimen
Folia Medica Indonesiana, 2021 Staphylococcus aureus (S. aureus) is the most common pathogen in humans that causes various infections. Variations in infections due to S. aureus are related to the presence of virulence factors, one of which is Toxic Shock Syndrome Toxin-1 (TSST-1 ...
Marinda Dwi Puspitarini +3 more
doaj +4 more sources
Candida albicans promotes TSST-1 production by Staphylococcus aureus through glucose depletion and relief of CcpA-mediated repression [PDF]
Journal of BacteriologyMenstrual toxic shock syndrome (mTSS) is a rare yet life-threatening disease that is caused when the opportunistic pathogenic bacterium Staphylococcus aureus releases the toxic shock syndrome toxin 1 (TSST-1) superantigen, which triggers systemic ...
Mathias Carriou +5 more
doaj +2 more sources