Results 11 to 20 of about 29,995,464 (183)

Molecular Genotyping of Tsst-1 Gene Staphylococcus Aureus from Clinical Specimen [PDF]

Folia Medica Indonesiana, 2021
Staphylococcus aureus (S. aureus) is the most common pathogen in humans that causes various infections. Variations in infections due to S. aureus are related to the presence of virulence factors, one of which is Toxic Shock Syndrome Toxin-1 (TSST-1 ...
Marinda Dwi Puspitarini, Kuntaman Kuntaman, Eddy Bagus Wasito, Wahyu Setyarini   +3 more
doaj   +5 more sources

Candida albicans promotes TSST-1 production by Staphylococcus aureus through glucose depletion and relief of CcpA-mediated repression [PDF]

Journal of Bacteriology
Menstrual toxic shock syndrome (mTSS) is a rare yet life-threatening disease that is caused when the opportunistic pathogenic bacterium Staphylococcus aureus releases the toxic shock syndrome toxin 1 (TSST-1) superantigen, which triggers systemic ...
Mathias Carriou, Cédric Badiou, Alexandre Soulard, Christophe d'Enfert, Karine Dufresne, Gérard Lina   +5 more
doaj   +3 more sources

Association of tsst-1 and pvl with mecA Genes among Clinical Staphylococcus aureus Isolates from a Tertiary Care Hospital

Journal of Pure and Applied Microbiology, 2019
To investigate the association of both tsst-1 and pvl with mecA genes in clinical Staphylococcus aureus (S. aureus) strains obtained from a tertiary care hospital, Mansoura-Egypt.
Amira M. Sultan, Yasmin Nabiel
doaj   +2 more sources

Modulatory Effects of Staphylococcal Superantigen TSST-1 on IGE Synthesis in Atopic Dermatitis [PDF]

Clinical Immunology and Immunopathology, 1995
Atopic dermatitis (AD) is a chronic skin disorder associated with elevated serum IgE and colonization of the skin by Staphylococi which secrete toxins with superantigenic activity. The present study examined the immunomodulatory effects of toxic shock syndrome toxin (TSST)-1, a prototypic superantigen, on IgE synthesis by interleukin (IL)-4-stimulated ...
M R, Lester, M F, Hofer, H, Renz, A E, Trumble, E W, Gelfand, D Y, Leung   +5 more
core   +4 more sources

Distribution of tsst-1 and mecA Genes in Staphylococcus aureus Isolated From Clinical Specimens. [PDF]

Jundishapur J Microbiol, 2016
Staphylococcus aureus is a harmful pathogen known to express numerous virulence factors and cause severe infections. High levels of methicillin-resistant Staphylococcus aureus (MRSA) strains are one of the important healthcare problems because of the inefficient treatment of these infections.The purpose of the current study is to evaluate the incidence
Zarei Koosha R, Mahmoodzadeh Hosseini H, Mehdizadeh Aghdam E, Ghorbani Tajandareh S, Imani Fooladi AA.   +4 more
europepmc   +4 more sources

Selective Expansion of TCR Vβ2⁺ Tregs and Impaired Lymphocyte TSST-1 Responsiveness in Bullous Pemphigoid Patients Colonised by Staphylococcus aureus. [PDF]

Exp Dermatol
ABSTRACT Bullous pemphigoid (BP) is an autoimmune blistering disease of the elderly who are frequently colonised by Staphylococcus aureus, particularly strains producing the superantigen toxic shock syndrome toxin‐1 (TSST‐1). Given the ability of TSST‐1 to engage the T cell receptor (TCR) Vβ2 chain, we investigated whether superantigen (SAg) exposure ...
Chen TY, Crowe TP, Fakhimi M, Poleksíc M, Kilgore SH, Schlievert PM, Fairley JA, Messingham KN.   +7 more
europepmc   +2 more sources

Elucidating the Staphylococcus aureus TSST-1 Regulatory Network as a Response to Vaginal pH. [PDF]

Mol Microbiol
Toxic shock syndrome toxin‐1 (TSST‐1) is a potent Staphylococcus aureus superantigen responsible for menstrual toxic shock syndrome (mTSS). Regulation of TSST‐1 is controlled by multiple systems including the stand‐alone transcriptional regulators CcpA and SarA and two‐component systems including the redox sensor SrrAB, the membrane stress sensor SaeRS,
Maduta CS, Walton NR, Barbosa EP, DeJong EN, Dufresne K, McCormick JK.   +5 more
europepmc   +2 more sources

Inhibition of Toxic Shock Syndrome-Associated Staphylococcus aureus by Probiotic Lactobacilli

Microbiology Spectrum, 2023
Staphylococcus aureus is a human pathogen with many infections originating on mucosal surfaces. One common group of S. aureus is the USA200 (CC30) clonal group, which produces toxic shock syndrome toxin-1 (TSST-1). Many USA200 infections occur on mucosal
Patrick M. Schlievert, Adriana V. Gaitán, Samuel H. Kilgore, Amy L. Roe, Johanna Maukonen, Liisa Lehtoranta, Donald Y. M. Leung, Daniel S. Marsman   +7 more
doaj   +1 more source

The effect of Staphylococcus aureus carriage in late pregnancy on antibody levels to staphylococcal toxins in cord blood and breast milk. [PDF]

, 2008
We investigated the effect of carriage of Staphylococcus aureus in the later stages of pregnancy on levels of antibody specific to the S. aureus toxins, staphylococcal enterotoxin B (SEB), staphylococcal enterotoxin C (SEC) and toxic shock syndrome toxin-
Morris, James A., Telford, David R., Lauder, Robert M., Harrison, Linda M.   +3 more
core   +4 more sources

Epithelial proinflammatory response and curcumin-mediated protection from staphylococcal toxic shock syndrome toxin-1. [PDF]

PLoS ONE, 2012
Staphylococcus aureus initiates infections and produces virulence factors, including superantigens (SAgs), at mucosal surfaces. The SAg, Toxic Shock Syndrome Toxin-1 (TSST-1) induces cytokine secretion from epithelial cells, antigen presenting cells ...
Matthew M Schaefers, Laura M Breshears, Michele J Anderson, Ying-Chi Lin, Alex E Grill, Jayanth Panyam, Peter J Southern, Patrick M Schlievert, Marnie L Peterson   +8 more
doaj   +1 more source