Results 51 to 60 of about 37,549 (151)

Multidrug resistant tuberculosis.

Indian pediatrics, 1999
Multidrug-resistant tuberculosis (MDR-TB) is defined as one that is resistant to both isoniazid and rifampicin regardless of its resistance to any other antituberculosis drugs. According to "Study on the incidence of drug resistance for new admissions" reported by TB Sanatorium Council in 1992 in Japan, no increase of incidence was observed in either ...
H, Saito, R, Amitani
  +6 more sources

Multidrug-resistant and heteroresistant Mycobacterium tuberculosis and associated gene mutations in Ethiopia

International Journal of Infectious Diseases, 2015
Background: The prevalence of multidrug-resistant tuberculosis (TB) among new and retreatment cases in 2011 in Ethiopia was 2.7% and 17.9%, respectively.
Daniel Mekonnen, Aschalew Admassu, Wondemagegn Mulu, Aranzazu Amor, Agustín Benito, Woynshet Gelaye, Fantahun Biadglegne, Bayeh Abera   +7 more
doaj   +1 more source

Contributions of Community Advisory Board and Experience of Study Participants in TB/MDR‐TB Clinical Trial Management in Addis Ababa, Ethiopia: A Qualitative Study

Developing World Bioethics, EarlyView.
ABSTRACT Community Advisory Boards (CABs), as a form of community engagement, provide an important mechanism to ensure that research aligns with community needs and priorities by representing broader community interests and guiding research accordingly.
Yemisrach Seralegne, Abaraham G/Medihin, Ermiyas Hundito, Hawult Adane, Bizunesh Sintayehu   +4 more
wiley   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

Being safe, feeling safe, and stigmatizing attitude among primary health care staff in providing multidrug-resistant tuberculosis care in Bantul District, Yogyakarta Province, Indonesia

Human Resources for Health, 2019
Introduction Patient-centered care approach in multidrug-resistant tuberculosis care requires health worker safety that covers both being safe and feeling safe to conduct the services. Stigma has been argued as a barrier to patient-centered care. However,
Ari Probandari, Hary Sanjoto, Melani Ratih Mahanani, Luthfi Azizatunnisa, Sampir Widayati   +4 more
doaj   +1 more source

Persistent Burkholderia cepacia Bacteremia in Reconstructive Surgery: Resistance to Ceftazidime/Avibactam and Co‐Trimoxazole With Risk of Infective Endocarditis—A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Persistent Burkholderia cepacia bacteremia in soft tissue infections creates diagnostic and therapeutic challenges due to its resistance profile and potential for endovascular involvement. Early culture‐guided therapy, multidisciplinary coordination, and vigilance for complications, such as infective endocarditis, are essential for achieving ...
Chukwuka Elendu, Dependable C. Amaechi, Tochi C. Elendu, Emmanuel C. Amaechi, Ijeoma D. Elendu, Adaobi S. Ikedilo   +5 more
wiley   +1 more source

Coexistence of Scrofuloderma and Lepromatous Leprosy in Reaction: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Leprosy and tuberculosis (TB) are both chronic granulomatous infections caused by bacilli of the genus Mycobacterium. The simultaneous occurrence of cutaneous tuberculosis and leprosy is rare. We report a 56‐year‐old male presenting with painful erythematous nodules and plaques over the face and extremities for 1 week, along with asymptomatic ...
Anupa Khadka, Punam Mishra, Akanshya Shrestha, Gunawati Chaulagain   +3 more
wiley   +1 more source

RESULTS OF CHEMOTHERAPY IN PATIENTS WITH MULTIDRUG-RESISTANT TUBERCULOSIS IN THE REGIONS OF THE RUSSIAN FEDERATION

Туберкулез и болезни лёгких, 2014
The paper analyzes the results of treatment in 5,396 patients with multidrug-resistant tuberculosis who were treated in the regions of the Russian Federation under the Global Fund Round 4 project based on the recommended World Health Organization ...
V. V. Testov, S. A. Sterlikov, I. A. Vasilyeva, V. V. Erokhin, T. Ch. Kesaeva   +4 more
doaj  

Issues of Tuberculosis Drug-Resistance in Kharkiv Region and in Ukraine

Infusion & Chemotherapy, 2019
Background. Multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis remain severe epidemic problems in the world. That’s why the purpose of our study was to investigate the dynamics of the incidence of multidrug-resistant and ...
O.S. Shevchenko, O.O. Pohorielova
doaj   +1 more source

Immune activation and response dynamics of human iPSC‐derived macrophages in tuberculosis infection models

Clinical &Translational Immunology, Volume 15, Issue 1, 2026.
In this study, we analysed the immune responses of blood‐derived monocyte macrophages and iPSC‐derived macrophages following BCG/HKMT infection. We found that iPSC‐derived macrophages displayed a markedly stronger activation profile, including faster migration, increased reactive oxygen species production, elevated apoptosis marker expression and ...
Daniela Paasch, Hannah Schevel, Andrea Riehle, Bibiana Costa, Hassan Toufaili, Tabea Gehnen, Julia Dahlmann, Andreas Pavlou, Anna‐Lena Neehus, Ariane Hai Ha Nguyen, Erika Schiering, Theresa Buchegger, Jacinta Bustamante, Gesine Hansen, Ulrich Kalinke, Erich Gulbins, Heike Grassmé, Nico Lachmann   +17 more
wiley   +1 more source