Results 81 to 90 of about 31,941 (191)

Factors associated with multidrug-resistant tuberculosis

IMC Journal of Medical Science, 2009
This case control study was conducted in selected centers of Dhaka City from March to July 2008 to determine the association of multidrug-resistant tuberculosis with the attributes related to treatment and socio-economic condition of tuberculosis ...
Md Nurul Amin, Md Anisur Rahman, Meerjady Sabrina Flora, Md Abul Kalam Azad   +3 more
doaj  

Relative bioavailability of delamanid 50 mg tablets dispersed in water in healthy adult volunteers

British Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 957-967, April 2025.
Aim Delamanid is a novel drug for the treatment of drug‐resistant tuberculosis, manufactured as 50‐mg solid and 25‐mg dispersible tablets. We evaluated the effects of dispersing the 50‐mg tablet, focusing on the relative bioavailability. Methods Delamanid, 50‐mg tablets administered dispersed vs swallowed whole, was investigated in a phase I, four ...
Yuanxi Zou, Veronique de Jager, Anneke C. Hesseling, Andreas H. Diacon, Lubbe Wiesner, Joni Mostert, Elin M. Svensson, Anthony Garcia‐Prats   +7 more
wiley   +1 more source

Multidrug and extensively drug-resistant tuberculosis from a general practice perspective

Infection and Drug Resistance, 2010
BM Yashodhara1, Choo Beng Huat1, Lakshmi Nagappa Naik1, Shashikiran Umakanth2, Manjunatha Hande2, Joseph M Pappachan31Department of Medicine, Melaka Manipal Medical College, Melaka, India; 2Department of Medicine, Kasturaba Medical College, Manipal ...
BM Yashodhara, Choo Beng Huat, Lakshmi Nagappa Naik, et al   +3 more
doaj  

Singularity and Symmetry Analyses for Tuberculosis Epidemics [PDF]

arXiv, 2014
We analyse the model of Tuberculosis due to Blower (Nature Medecine 1(8) 815-821) from the point of view of symmetry and singularity analysis. From the study we provide a demonstration of the integrability of the model to present an explicit solution.
arxiv  

Antibiotic‐Induced Dysbiosis of the Gut Microbiota Shifts Host Tryptophan Metabolism and Increases the Susceptibility of Mice to Pulmonary Infection With Pseudomonas aeruginosa

Immunology, EarlyView.
Antibiotic‐induced dysbiosis of the gut microbiota shifts host tryptophan metabolism and impairs the innate immune response during Pseudomonas aeruginosa pulmonary infection. (A) Eubiosis: During eubiosis, the intestinal microbiota metabolises tryptophan into indole metabolites, which keeps tryptophan levels within normal serum concentrations. However,
Camila Bernardo de Brito, Raquel Duque do Nascimento Arifa, Rafael de Oliveira Bezerra, Carlos Eduardo Dias Igídio, Bárbara Maria de Amorim‐Santos, Anna Clara Paiva de Menezes Santos, Larissa Mendes Barbosa, João Paulo Pezzini Barbosa, Larissa Marcely Gomes Cassiano, Markus Kohlhoff, Micheli Fagundes, Rafaela Ribeiro Álvares Batista, Celso Martins Queiroz‐Junior, Alessandra M. Saliba, Juliana Divina Almeida Raposo, Fernão Castro Braga, Roney Santos Coimbra, Mauro Martins Teixeira, Caio Tavares Fagundes, Danielle G. Souza   +19 more
wiley   +1 more source

Impact of COVID-19 on diagnosis of tuberculosis, multidrug-resistant tuberculosis, and on mortality in 11 countries in Europe, Northern America, and Australia. A Global Tuberculosis Network study. [PDF]

Int J Infect Dis, 2023
Nalunjogi J, Mucching-Toscano S, Sibomana JP, Centis R, D'Ambrosio L, Alffenaar JW, Denholm J, Blanc FX, Borisov S, Danila E, Duarte R, García-García JM, Goletti D, Ong CWM, Rendon A, Thomas TA, Tiberi S, van den Boom M, Sotgiu G, Migliori GB, Global Tuberculosis Network.   +20 more
europepmc   +1 more source

Gromomycins: An Unprecedented Class of Triterpene Antibiotics Produced by a Novel Biosynthetic Pathway

Angewandte Chemie, Volume 137, Issue 22, May 26, 2025.
Gromomycins represent a novel class of pentacyclic triterpene antibiotics with a unique biosynthetic pathway independent of the squalene route. These compounds exhibit potent activity against drug‐resistant Gram‐positive pathogens, including MRSA, and their unprecedented cyclization mechanism provides new insight into bacterial triterpene biosynthesis.
Stepan Tistechok, Dmytro Bratiichuk, Hilda Sucipto, Nils Gummerlich, Marc Stierhof, Oleksandr Gromyko, Franziska Fries, Victor Fedorenko, Rolf Müller, Josef Zapp, Maksym Myronovskyi, Andriy Luzhetskyy   +11 more
wiley   +2 more sources

A Data Mining Approach to the Diagnosis of Tuberculosis by Cascading Clustering and Classification [PDF]

Journal of computing, volume 3, issue 4,April 2011, ISSN 2151-9617, 2011
In this paper, a methodology for the automated detection and classification of Tuberculosis(TB) is presented. Tuberculosis is a disease caused by mycobacterium which spreads through the air and attacks low immune bodies easily. Our methodology is based on clustering and classification that classifies TB into two categories, Pulmonary Tuberculosis(PTB ...
arxiv  

Multi‐drug resistance and compensatory mutations in Mycobacterium tuberculosis in Vietnam

Tropical Medicine &International Health, Volume 30, Issue 5, Page 426-436, May 2025.
Abstract Background Vietnam is a hotspot for the emergence and spread of multidrug‐resistant Mycobacterium tuberculosis. This study aimed to perform a retrospective study on the compensatory evolution in multidrug‐resistant M. tuberculosis strains and the association with drug‐resistant mutations and M. tuberculosis genotypes.
Quang Huy Nguyen, Thi Van Anh Nguyen, Anne‐Laure Bañuls   +2 more
wiley   +1 more source

Epidemic characteristics and drug resistance of tuberculosis in North China

Heliyon, 2020
To analyze the epidemiological characteristics and drug resistance of tuberculosis (TB) patients in northern China. The epidemiological characteristics of 620 patients with tuberculosis from 2014 to 2016 were analyzed, including gender, age, occupation ...
Zheng Qi, Xi Gao, Yan-fu Wang, Chang Liu
doaj