Results 91 to 100 of about 1,134,717 (381)
Туберкулез и болезни лёгких, 2017 Specific personal features of 296 children and adolescents exposed to tuberculosis and those with unidentified exposure were comparatively analyzed. Children with unidentified exposure demonstrated psychic tension, poor self-control, poorly developed ...
N. V. Zolotova +5 more
doaj +1 more source
Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications
Advanced Science, EarlyView.HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang +5 more
wiley +1 more source
Инфекция и иммунитет, 2018 In 2015, more than 10% of tuberculosis (TB)-related deaths were attributable to M. tuberculosis with multiple drug-resistance (MDR-TB) and extensively drug-resistance (XDR-TB) (WHO 2016).
V. V. Eremeev +4 more
doaj +1 more source
TBNet:Pulmonary Tuberculosis Diagnosing System using Deep Neural Networks [PDF]
arXiv, 2019 Tuberculosis is a deadly infectious disease prevalent around the world. Due to the lack of proper technology in place, the early detection of this disease is unattainable. Also, the available methods to detect Tuberculosis is not up-to a commendable standards due to their dependency on unnecessary features, this make such technology obsolete for a ...
arxiv
Epidemic modelling of bovine tuberculosis in cattle herds and badgers in Ireland [PDF]
arXiv, 2020 Bovine tuberculosis, a disease that affects cattle and badgers in Ireland, was studied via stochastic epidemic modeling using incidence data from the Four Area Project (Griffin et al., 2005). The Four Area Project was a large scale field trial conducted in four diverse farming regions of Ireland over a five-year period (1997-2002) to evaluate the ...
arxiv
Label-free optical vibrational spectroscopy to detect the metabolic state of M. tuberculosis cells at the site of disease [PDF]
, 2017 Tuberculosis relapse is a barrier to shorter treatment. It is thought that lipid rich cells, phenotypically resistant to antibiotics, may play a major role. Most studies investigating relapse use sputum samples although tissue bacteria may play an important role. We developed a non-destructive, label-free technique combining wavelength modulated Raman (
arxiv +1 more source
Advanced Science, EarlyView.In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han +10 more
wiley +1 more source
Cancer Communications, Volume 42, Issue 12, Page 1314-1330, December 2022., 2022 Abstract Background Treatment options for Chinese patients with locally advanced or metastatic squamous‐cell non‐small‐cell lung cancer (sqNSCLC) after failure of first‐line chemotherapy are limited. This study (ORIENT‐3) aimed to evaluate the efficacy and safety of sintilimab versus docetaxel as second‐line treatment in patients with locally advanced ...
Yuankai Shi +45 more
wiley +1 more source
Intraoperative use of a polymer mesh implant in common destructive pulmonary tuberculosis complicated by empyema with bronchopleural fistula [PDF]
Наука и инновации в медицинеThe article observes a clinical case – intraoperative use of anterior mediastinal plastic surgery with a mesh implant for transsternal occlusion of the main bronchus in a patient with widespread destructive pulmonary tuberculosis complicated by ...
Ruslan V. Tarasov +4 more
doaj +1 more source
Optimal Control for Tuberculosis with Exogenous Reinfection and Stigmatization [PDF]
arXiv, 2021 The effect of stigmatization is hindering the control of diseases. Especially in the case of exogenous reinfection, this effect can play a massive role. We develop in this paper, based on a tuberculosis model of Feng et.al. a model with exogenous reinfection and stigmatization.
arxiv