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Optimal control strategies for tuberculosis treatment: a case study in Angola [PDF]
We apply optimal control theory to a tuberculosis model given by a system of ordinary differential equations. Optimal control strategies are proposed to minimize the cost of interventions. Numerical simulations are given using data from Angola.
arxiv +1 more source
Tuberculosis (TB) in children is a neglected aspect of the TB epidemic despite it constituting 20% or more of all TB cases in many countries with high TB incidence. Childhood TB is a direct consequence of adult TB but remains overshadowed by adult TB because it is usually smear-negative.
Esposito, Susanna Maria Roberta+2 more
openaire +8 more sources
Household screening and multidrug-resistant tuberculosis [PDF]
Of the estimated half a million people who develop multidrug resistant (MDR) tuberculosis each year, less than 7% are diagnosed and only 1 in 5 of these have access to eff ective treatment.1 To control this epidemic, dramatically increased efforts are ...
Becerra+9 more
core +2 more sources
Problems of anti-tuberculosis therapy in patients on hemodialysis
The objective: to determine possibility of prescribing and safety of various anti-tuberculosis drugs and their combinations as part of a therapeutic or preventive course of anti-tuberculosis therapy (ATBT) in patients with end-stage chronic kidney ...
O. M. Gordeeva+4 more
doaj +1 more source
Mycobacterium tuberculosis type VII secretion system effectors differentially impact the ESCRT endomembrane damage response [PDF]
Mycobacterium tuberculosis causes tuberculosis, which kills more people than any other infection. M. tuberculosis grows in macrophages, cells that specialize in engulfing and degrading microorganisms.
Hanson, Phyllis I+7 more
core +2 more sources
This work presents a systematic characterization of an emerging polymer platform, off‐stoichiometry thiol‐ene, in terms of its ability to support the formation, growth, and metabolic activity of Staphylococcus aureus biofilms. The findings indicate that thiol‐enes promote S.
Jéssica Amorim+6 more
wiley +1 more source
Four Months of Rifampin or Nine Months of Isoniazid for Latent Tuberculosis in Adults
BACKGROUND A 9‐month regimen of isoniazid can prevent active tuberculosis in persons with latent tuberculosis infection. However, the regimen has been associated with poor adherence rates and with toxic effects.
D. Menzies+28 more
semanticscholar +1 more source
PSYCHOLOGICAL REHABILITATION MODEL OF PULMONARY TUBERCULOSIS PATIENTS IN IN-PATIENT DEPARTMENT
The article describes the issues of psychological rehabilitation of pulmonary tuberculosis patients and summarizes the practical experience of authors in the establishment of psychological support services in a TB clinic.
N. V. Zolotovа+5 more
doaj +1 more source
Background Tuberculous pleural effusion (TPE) is the most common extrapulmonary manifestation and may have lasting effect on lung function. However conventional diagnostic tests for TPE register multiple limitations.
Xinting Yang+14 more
doaj +1 more source
Aspects of Stage-by-Stage Diagnosis of Pulmonary Mycobacteriosis in Real Clinical Practice
The objective: to analyze the effectiveness of etiological verification of pulmonary mycobacteriosis when using various biological materials at different diagnostic stages.Subjects and Methods.
N. L. Karpina+4 more
doaj +1 more source