Results 181 to 190 of about 1,339,212 (357)

C13‐Deacylase from Nocardioides albus Resp. Streptomyces sp., Catalyzing Side Chain Hydrolysis on the Taxane Core

open access: yesChemCatChem, EarlyView.
An enzyme that has been identified and characterized as capable of hydrolyzing paclitaxel (Taxol), a key anticancer drug derived from Pacific yew (Taxus brevifolia) has been identified. Molecular docking (MD) simulations map the catalytic triad and critical residues that drive substrate‐enzyme interactions. The findings indicate the catalytic potential
Jinfen Su   +3 more
wiley   +1 more source

High Sensitivity L‐Cysteine Indium Telluriselenide Quantum Dot‐Inspired Aptasensor for Interferon Gamma TB Biomarker

open access: yesChemElectroChem, EarlyView.
An electrochemical interferon‐gamma (IFN‐γ) aptasensor is developed with L‐cysteine‐indium telluriselenide quantum dot (QD) and 24 mer guanine‐thymine DNA aptamer. The aptasensor exhibits high sensitivity in buffer and human serum samples. From calibration analysis, the limit of detection of the aptasensor is 0.312 pg mL−1 IFN‐γ, which indicates good ...
Kaylin Cleo Januarie   +8 more
wiley   +1 more source

Laser‐Induced Graphene for Early Disease Detection: A Review

open access: yesChemElectroChem, Volume 12, Issue 6, March 15, 2025.
Laser‐induced graphene (LIG) has emerged as a superior alternative to conventionally synthesized graphene due to its flexibility, cost‐effectiveness, scalability, high conductivity, and the ability to customize its properties for various applications. This review highlights LIG′s transformative potential in electrochemical biosensing, focusing on early
Sri Ramulu Torati, Gymama Slaughter
wiley   +1 more source

Pattern of ethionamide susceptibility and its association with isoniazid resistance among previously treated tuberculosis patients from India

open access: yesBrazilian Journal of Infectious Diseases
Rajagopalan Lakshmi   +6 more
doaj   +1 more source

THE EFFECT OF DEVELOPMENT OF GEOGRAPHY, VITAMIN D, WEALTH, AND AGRICULTURAL PRODUCTIVITY ON TUBERCULOSIS MORTALITY: THE CASE OF THE 19TH CENTURY US [PDF]

open access: yes
Tuberculosis remains a major cause of international mortality, and researchers and policy advocates continue to seek a cost effective prevention and treatment.
Scott Alan Carson
core  

Synthesis, Antimycobacterial Activity, and Computational Insight of Novel 1,4‐Benzoxazin‐2‐one Derivatives as Promising Candidates against Multidrug‐Resistant Mycobacterium Tuberculosis

open access: yesChemMedChem, EarlyView.
A series of 14 novel 1,4‐benzoxazinone derivatives is tested against various strains of Mycobacterium tuberculosis. All compounds show high activity against all tested strains, particularly the resistant strains. Additionally, the novel derivatives exhibit low cytotoxicity toward mammalian Vero cells.
Maria Grazia Mamolo   +6 more
wiley   +1 more source

TUBERCULOSIS OF THE THYROID GLAND

open access: green, 1926
Frederick A. Coller, Charles Huggins
openalex   +2 more sources

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