Results 61 to 70 of about 1,339,212 (357)
Advanced Science, EarlyView.CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen +10 more
wiley +1 more source
Deep Breathing Relaxation Techniques Improve Emotional Control on Tuberculosis Patients [PDF]
, 2016 Tuberculosis is an infectious disease caused by Tuberculosis Mycobacterium. Based on WHO report in 2014, the world population suffering from tuberculosis were 9.6 million people while in Indonesia it was amounted 324 539 people.
Dwidiyanti, M. (Meidiana) +2 more
core
Mediterranean Journal of Hematology and Infectious Diseases, 2013 Tuberculosis (TB) in children is a neglected aspect of the TB epidemic despite it constituting 20% or more of all TB cases in many countries with high TB incidence. Childhood TB is a direct consequence of adult TB but remains overshadowed by adult TB because it is usually smear-negative.
Esposito, Susanna Maria Roberta +2 more
openaire +8 more sources
Advanced Science, EarlyView.The tumor‐associated macrophages (TAMs) in lung cancer tissues exhibit active cystine metabolism. Restricting cystine concentration in macrophages induces M1 phenotypic polarization and upregulation of PD‐L1 expression through the GSH‐NF‐κB signaling pathway.
Yun Xu +20 more
wiley +1 more source
Вестник рентгенологии и радиологии, 2021 The paper describes a clinical case of hypersensitivity pneumonitis in a young patient during the COVID-19 pandemic when the patient having complaints of dyspnea and interstitial lung changes as ground glass opacity was initially unambiguously diagnosed ...
N. L. Karpina +6 more
doaj +1 more source
Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives
Advanced Science, EarlyView.Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu +13 more
wiley +1 more source
Adverse reactions in the treatment of patients with non-tuberculous lung mycobacterial pulmonary disease and the possibility of their solution [PDF]
Терапевтический архивAim. To study the adverse reactions that develop as a result of complex antibiotic therapy in patients with non-tuberculous lung mycobacterial (NTML) and to determine methods for their elimination without compromising the effectiveness of NTML treatment.
Elena B. Vladimirova +6 more
doaj +1 more source
Antibacterial activity of the novel compound Sudapyridine (WX-081) against Mycobacterium abscessus
Frontiers in Cellular and Infection Microbiology, 2023 ObjectiveThis study aimed to investigate sudapyridine (WX-081) antibacterial activity against Mycobacterium abscessus in vitro and its effect on in vivo bacterial growth and host survival using a zebrafish model of M. abscessus infection.MethodsWX-081 in
Wenjuan Nie +9 more
doaj +1 more source
Transmission of multidrug-resistant tuberculosis in the UK: a cross-sectional molecular and epidemiological study of clustering and contact tracing [PDF]
, 2014 BACKGROUND: Between 2000 and 2012 the number of multidrug-resistant (MDR) tuberculosis cases in the UK increased from 28 per year to 81 per year. We investigated the proportion of MDR tuberculosis cases arising from transmission in the UK and associated ...
Abubakar, I +6 more
core +1 more source
Advanced Science, EarlyView.Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li +11 more
wiley +1 more source