Results 71 to 80 of about 769,512 (313)

An Inflammation‐Targeting Engineered Probiotic Escherichia coli Nissle 1917 with High Anti‐TNF‐α Nanobody Secretion Efficacy Alleviates Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
Ulcerative colitis therapy requires precise drug targeting. This study engineers a probiotic E. coli Nissle 1917 to surface‐display ANXA5, enabling specific binding to phosphatidylserine (PS) exposed on inflamed colonic epithelium for enhanced targeting and colonization.
Siqi Hua   +6 more
wiley   +1 more source

Construction and Validation of a Nomogram-Based Predictive Model for Acute Kidney Injury Caused by Drug Resistance to Tuberculosis

open access: yesInternational Journal of General Medicine
Mo Deng,* Na Han, Mishan Jia, Zhiqing Zheng, Yanqing Tian, Hui Wang,* Li Feng Department of Tuberculosis, Affiliated Hospital of Hebei University, Baoding, Hebei, 071000, People’s Republic of China*These authors contributed ...
Deng M   +6 more
doaj  

Prognostic Value of Serum Insulin‐Like Growth Factor‐1 in Patients With Anal Fistula Treated by Incision‐Thread‐Drawing Surgery

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
IGF‐1 levels above 174.9 ng/mL were associated with better wound healing and lower postoperative inflammation. Higher IGF‐1 levels correlated with improved anal function at 7 and 14 days post‐surgery. ABSTRACT Background Anal fistula is a chronic condition characterized by an abnormal tract between the anal canal and perianal skin, often leading to ...
Zhijun Wu, Xuexue Yin, Jing Li
wiley   +1 more source

Intelligent Theranostic Systems Enabled by Aggregation‐Induced Emission in Precision Medicine

open access: yesAggregate, EarlyView.
Aggregation‐induced emission (AIE) luminogens are driving a new generation of intelligent theranostic systems that integrate high‐fidelity imaging and multifunctional therapy. This review highlights how AIEgens, through restriction of intramolecular motion (RIM), enable deep‐tissue NIR‐II imaging, ultrasensitive biosensing, CRISPR‐assisted gene ...
Qinqin Huang   +7 more
wiley   +1 more source

Diagnosis of Bactec samples by immunoglobulins of mouse hyperimmune sera obtained against modified antigens of the cell wall of Mycobacterium tuberculosis

open access: yesТуберкулез и болезни лёгких, 2019
The objective: using double-site enzyme immunoassay (ELISA) to evaluate the specificity of the antigens of digestive and chemically modified cell walls (CW) of M. tuberculosis.Subjects and methods.
I. V. Kozlova   +4 more
doaj   +1 more source

Sulfur Dioxide‐ and Fluoride‐Associated Declines in Lung Function Over an 11‐Year Observation Among Aluminum Smelter Workers

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Work exposure‐related declines in lung function among aluminum smelter workers are well documented, yet task‐varying exposures are likely to contribute differently to respiratory outcomes. This study aimed to assess the association between potroom exposure and lung function changes over time among aluminum smelter workers. Methods A
Edite Macaringue Raja   +2 more
wiley   +1 more source

The clinical case of effective treatment of pulmonary tuberculosis in the female adolescent after kidney transplantation

open access: yesТуберкулез и болезни лёгких, 2016
The article presents the clinical case of successful treatment of pulmonary tuberculosis in the female adolescent with concurrent chronic kidney disease.
E. S. Ovsyankina   +5 more
doaj  

New approaches to treating chronic obstructive pulmonary disease with Colla corii asini

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang   +5 more
wiley   +1 more source

RANGING RESULTS FOR TERRITORIES OF SIBERIAN AND FAR EASTERN FEDERAL DISTRICTS AIMED AT THE EVALUATION OF THE IMPACT OF TUBERCULOSIS CONTROL MEASURES ON THE EPIDEMIC SITUATION

open access: yesТуберкулез и болезни лёгких, 2016
Efficiency of tuberculosis control measures was comprehensively evaluated in the Russian regions (totally 21 regions) within Siberian and Far Eastern Federal Districts by means of ranging the sets of indicators.
T. V. Аlekseeva   +4 more
doaj   +1 more source

TUBERCULOSIS IN THE NEGRO. [PDF]

open access: green, 1903
SEALE HARRIS
openalex   +1 more source

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