Results 71 to 80 of about 1,198,187 (379)
Angewandte Chemie International Edition, Volume 61, Issue 51, December 19, 2022., 2022 Corramycin is a novel natural product produced by the myxobacterium Corallococcus coralloides. The structure, extraordinary total synthesis and biosynthesis of the antibiotic is described for the first time. Its promise as an in vivo septicemia model, the absence of cross‐resistance with commonly used antibiotic classes, and the lack of cytotoxicity ...
Cédric Couturier +32 more
wiley +1 more source
Туберкулез и болезни лёгких, 2016 Goal of the study: to investigate the changes in ventilation and gas exchange function of the lungs before and after 1-1.5 months after installation of endobronchial valve (EV) aimed at cavity healing in pulmonary destructive tuberculosis patients ...
L. A. Popova +5 more
doaj +1 more source
Household screening and multidrug-resistant tuberculosis [PDF]
, 2010 Of the estimated half a million people who develop multidrug resistant (MDR) tuberculosis each year, less than 7% are diagnosed and only 1 in 5 of these have access to eff ective treatment.1 To control this epidemic, dramatically increased efforts are ...
Becerra +9 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.Helicobacter pylori gastric infection is widespread and recurrency is common, fuelled by bacterial resistance to antibiotics. Therefore, specific and noninducing resistance alternative treatments are an urgent need. Taking advantage of this gastric pathogen auxotrophy for cholesterol, a “trojan horse” strategy for H.
Ana Sofia Pinho +6 more
wiley +1 more source
The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis
Angewandte Chemie International Edition, Volume 62, Issue 3, January 16, 2023., 2023 The cytochrome P450 enzyme AbyV catalyses a key epoxidation in the final stages of the biosynthesis of the spirotetronate antibiotic abyssomicin C. Combining structural and computational data with a 13C labelling strategy was found to be a powerful approach to interrogate the biotransformation and determine the precise function of the enzyme.
Andrew J. Devine +13 more
wiley +1 more source
Туберкулез и болезни лёгких, 2016 Goal of the study: to investigate structural and functional specific features of macrophages and cytokine profiles of bronchoalveolar lavage in new and relapsing respiratory sarcoidosis (RS).Materials and methods.
N. G. Demyanenko +5 more
doaj +1 more source
Optimal control strategies for tuberculosis treatment: a case study in Angola [PDF]
Numer. Algebra Control Optim. 2 (2012), no. 3, 601--617, 2012 We apply optimal control theory to a tuberculosis model given by a system of ordinary differential equations. Optimal control strategies are proposed to minimize the cost of interventions. Numerical simulations are given using data from Angola.
arxiv +1 more source
Mediterranean Journal of Hematology and Infectious Diseases, 2013 Tuberculosis (TB) in children is a neglected aspect of the TB epidemic despite it constituting 20% or more of all TB cases in many countries with high TB incidence. Childhood TB is a direct consequence of adult TB but remains overshadowed by adult TB because it is usually smear-negative.
Esposito, Susanna Maria Roberta +2 more
openaire +8 more sources
Advanced Healthcare Materials, EarlyView.This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey +5 more
wiley +1 more source
Mycobacterium tuberculosis type VII secretion system effectors differentially impact the ESCRT endomembrane damage response [PDF]
, 2018 Mycobacterium tuberculosis causes tuberculosis, which kills more people than any other infection. M. tuberculosis grows in macrophages, cells that specialize in engulfing and degrading microorganisms.
Hanson, Phyllis I +7 more
core +2 more sources