Results 81 to 90 of about 44,225 (262)

Prevalence of Nontuberculous Mycobacteria Infection, China, 2004–2009

Emerging Infectious Diseases, 2012
Hui Jing, Haiying Wang, Yan Wang, Yunfeng Deng, Xinxin Li, Zhimin Liu, Edward A. Graviss, Xin Ma   +7 more
doaj   +1 more source

The toxin–antitoxin complex Fic‐1–AntF functions as a deAMPylase that regulates the activity of DNA gyrase

mLife, EarlyView.
Abstract Toxin–antitoxin (TA) systems found in diverse bacteria play important roles in their adaptation to changing environments. The toxin of the Fic‐1–AntF TA pair from Pseudomonas bijieensis strain 2P24 inhibits bacterial DNA replication by attacking the subunit B of DNA gyrase (GyrB) via AMPylation, while the antitoxin AntF blocks its enzymatic ...
Furong Chen, Liwei Guo, Canhua Lu, Wenjun Jiang, Zhao‐Qing Luo, Junfeng Liu, Li‐Qun Zhang   +6 more
wiley   +1 more source

Potential of Pan-Tuberculosis Treatment to Drive Emergence of Novel Resistance

Emerging Infectious Diseases
New tuberculosis (TB) drugs with little existing antimicrobial resistance enable a pan-TB treatment regimen, intended for universal use without prior drug-susceptibility testing.
C. Finn McQuaid, Theresa S. Ryckman, Nicolas A. Menzies, Richard G. White, Ted Cohen, Emily A. Kendall   +5 more
doaj   +1 more source

Investigating Tuberculosis Dynamics Under Various Control Strategies: A Comprehensive Analysis Using Real Statistical Data

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In the present investigation, a mathematical model with vaccination, treatment, and environmental impact under real data is presented. Initially, we present the model without any interventions, followed by an examination of its equilibrium points.
Bashir Al‐Hdaibat, Mahmoud H. DarAssi, Irfan Ahmad, Muhammad Altaf Khan, Reem Algethamie   +4 more
wiley   +1 more source

Unveiling Saint Theobald: A Multidisciplinary Bioanthropological Investigation

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT Saint Theobald of Provins (1033–1066), a French nobleman who embraced voluntary poverty, hermitism, and pilgrimage, represents an early figure in the medieval ascetic movement. He holds historical significance for the diffusion of 11th‐century ascetic ideals, as a hermit saint associated with the Camaldolese order and venerated across northern
Nicola Carrara, Cicero Moraes, Luca Bezzi, Alberto Zanatta, Luca Pagani, Gilberto Artioli, Cinzia Scaggion   +6 more
wiley   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Distinguishing Nontuberculous Mycobacteria from Multidrug-Resistant Mycobacterium tuberculosis, China

Emerging Infectious Diseases, 2014
Kaijin Xu, Sheng Bi, Zhongkang Ji, Haiyang Hu, Feisu Hu, Beiwen Zheng, Bing Wang, Jingjing Ren, Shigui Yang, Min Deng, Ping Chen, Bing Ruan, Jifang Sheng, Lanjuan Li   +13 more
doaj   +1 more source

The Mycobacterium tuberculosis Rv0132c Gene Product Mtb‐FGD2 Can Act as an F420‐Dependent Glucose Dehydrogenase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi, Matthew Snee, Richard B. Tunnicliffe, Linus O. Johanissen, Matthew J. Cliff, Colin W. Levy, Derren J. Heyes, Marina Golovanova, Thomas A. Jowitt, Sam Hay, Andrew W. Munro, Jonathan P. Waltho, David Leys   +12 more
wiley   +1 more source

Estimating the seroprevalence of Mycobacterium bovis infection in a wild deer population in southwest England

Veterinary Record, EarlyView.
Abstract Background In England, transmission of Mycobacterium bovis between cattle and certain species of free‐roaming, wild deer has been implicated in some endemic bovine tuberculosis (bTB) regions. However, there are still data and knowledge gaps regarding the role of deer in the epidemiology of this disease.
Rachel Jinks, Alison Hollingdale, Rachelle Avigad, Juan Velarde, Chris Pugsley, Ricardo de la Rua‐Domenech, Charlotte Pritchard, Tony Roberts, Julia Pastor, Nick Robinson, Ruth Maynes, Susan Withenshaw, Graham Smith   +12 more
wiley   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, EarlyView.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source