Results 41 to 50 of about 436,730 (400)
Surface topography of microtubule walls decorated with monomeric and dimeric kinesin constructs [PDF]
, 2000 The surface topography of opened-up microtubule walls (sheets) decorated with monomeric and dimeric kinesin motor domains was investigated by freeze-drying and unidirectional metal shadowing.
Doerhoefer, Monika +6 more
core +2 more sources
Frontiers in Molecular Biosciences, 2020 Although it is known crocin, a hydrophilic compound from the herbal plant Crocus sativus L., has promising antitumor activity, the detailed mechanism of its antitumor activity was not well understood.
Ze Wang +4 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2014 Tau-tubulin kinase (TTBK) belongs to casein kinase superfamily and phosphorylates microtubule-associated protein tau and tubulin. TTBK has two isoforms, TTBK1 and TTBK2, which contain highly homologous catalytic domains but their non-catalytic domains are distinctly different.
Seiko eIkezu +2 more
openaire +4 more sources
TTC5 mediates autoregulation of tubulin via mRNA degradation
Science, 2019 Mechanism of tubulin autoregulation Cells tightly control the abundance of key housekeeping factors, such as ribosomes and chaperones, to maintain them at optimal levels needed for homeostasis.
Zhewang Lin +6 more
semanticscholar +1 more source
Microtubules in Bacteria: Ancient Tubulins Build a Five-Protofilament Homolog of the Eukaryotic Cytoskeleton [PDF]
, 2011 Microtubules play crucial roles in cytokinesis, transport, and motility, and are therefore superb targets for anti-cancer drugs. All tubulins evolved from a common ancestor they share with the distantly related bacterial cell division protein FtsZ, but ...
A Briegel +66 more
core +5 more sources
Honeybee Brain Oscillations Are Generated by Microtubules. The Concept of a Brain Central Oscillator
Frontiers in Molecular Neuroscience, 2021 Microtubules (MTs) are important structures of the cytoskeleton in neurons. Mammalian brain MTs act as biomolecular transistors that generate highly synchronous electrical oscillations. However, their role in brain function is largely unknown.
Brenda C. Gutierrez +6 more
doaj +1 more source
Solitonic Effects of the Local Electromagnetic Field on Neuronal Microtubules [PDF]
, 2007 Current wisdom in classical neuroscience suggests that the only direct action of the electric field in neurons is upon voltage-gated ion channels which open and close their gates during the passage of ions.
Georgiev, Danko +2 more
core +1 more source
Archaeal origin of tubulin [PDF]
Biology Direct, 2012 Tubulins are a family of GTPases that are key components of the cytoskeleton in all eukaryotes and are distantly related to the FtsZ GTPase that is involved in cell division in most bacteria and many archaea. Among prokaryotes, bona fide tubulins have been identified only in bacteria of the genus Prosthecobacter. These bacterial tubulin genes appear to
Eugene V. Koonin, Natalya Yutin
openaire +3 more sources
Pretubulysin derived probes as novel tools for monitoring the microtubule network via activity-based protein profiling and fluorescence microscopy [PDF]
, 2012 Microtubules (mt) are highly dynamic polymers composed of alpha- and beta-tubulin monomers that are present in all dividing and non-dividing cells. A broad variety of natural products exists that are known to interfere with the microtubule network, by ...
Burkhart, Jens L. +7 more
core +1 more source
Journal of Cell Biology, 2018 We used electron tomography to examine microtubules (MTs) growing from pure tubulin in vitro as well as two classes of MTs growing in cells from six species.
J. McIntosh +8 more
semanticscholar +1 more source