Results 31 to 40 of about 290,382 (301)

Mechanism of Tubulin Oligomers and Single-Rings Disassembly Catastrophe [PDF]

open access: yes, 2022
Cold tubulin dimers coexist with tubulin oligomers and single-rings. These structures are involved in microtubule assembly, however, their dynamics are poorly understood.
Raviv, Dharan   +5 more
core   +1 more source

Vimentin Plays a Crucial Role in Fibroblast Ageing by Regulating Biophysical Properties and Cell Migration

open access: yesCells, 2019
Ageing is the result of changes in biochemical and biophysical processes at the cellular level that lead to progressive organ decline. Here we focus on the biophysical changes that impair cellular function of human dermal fibroblasts using donors of ...
Kristina Sliogeryte, Núria Gavara
doaj   +1 more source

Design, Synthesis and In Vitro Biological Activity of Novel C-7 Methylene Congeners of Furanoallocolchicinoids

open access: yesPharmaceutics, 2023
A series of novel heterocyclic colchicine derivatives bearing a C-7 methylene fragment were synthesized via Wittig, Horner–Wadsworth–Emmons and Nenajdenko–Shastin olefination approaches.
Iuliia A. Gracheva   +5 more
doaj   +1 more source

Anti-tubulin-α-1cantibody levels in patients and healthy controls. [PDF]

open access: yes, 2018
The sensitivity and specificity of tubulin-α-1c antibody in the diagnosis of BD were 61.36% and 88.4% respectively. (BD 44, SLE 51, RAU 32, HC 59, AASV 25, TA 13).
Cibo Huang (444680)   +9 more
core   +1 more source

Surface topography of microtubule walls decorated with monomeric and dimeric kinesin constructs [PDF]

open access: yes, 2000
The surface topography of opened-up microtubule walls (sheets) decorated with monomeric and dimeric kinesin motor domains was investigated by freeze-drying and unidirectional metal shadowing.
Mandelkow, Eckhard   +6 more
core   +1 more source

Structural state recognition facilitates tip tracking of EB1 at growing microtubule ends

open access: yeseLife, 2019
The microtubule binding protein EB1 specifically targets the growing ends of microtubules in cells, where EB1 facilitates the interactions of cellular proteins with microtubule plus-ends.
Taylor A Reid   +9 more
doaj   +1 more source

MOESM3 of A novel resveratrol derivative induces mitotic arrest, centrosome fragmentation and cancer cell death by inhibiting γ-tubulin [PDF]

open access: yes, 2019
Additional file 3: Figure S3. Localization of different spindle pole proteins in 3,4,4′-TMS treated cells. HCT116 cells were exposed to 40 μM 3,4,4′-TMS and then immunostained with anti-Aurora A and anti-α-tubulin antibodies, anti-TPX2 and anti-α-tubulin
Zulema Percario (6574118)   +8 more
core   +1 more source

Role of Nuclear Lamin A/C in the Regulation of Nav1.5 Channel and Microtubules: Lesson From the Pathogenic Lamin A/C Variant Q517X

open access: yesFrontiers in Cell and Developmental Biology, 2022
In this work, we studied an lmna nonsense mutation encoding for the C-terminally truncated Lamin A/C (LMNA) variant Q517X, which was described in patients affected by a severe arrhythmogenic cardiomyopathy with history of sudden death. We found that LMNA
Roberta De Zio   +10 more
doaj   +1 more source

Phenotype difference of BD patients who are anti-tubulin-α-1c positive and negative. [PDF]

open access: yes, 2018
Phenotype difference of BD patients who are anti-tubulin-α-1c positive and negative.
Cibo Huang (444680)   +9 more
core   +1 more source

Hierarchical Assembly Pathways of Spermine Induced Tubulin Conical-Spiral Architectures [PDF]

open access: yes, 2020
Tubulin, an essential cytoskeletal protein, assembles into various morphologies by interacting with cellular factors. Spermine, an endogenous polyamine, promotes and stabilizes tubulin assemblies.
Raviv, Dharan   +5 more
core   +1 more source

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