Results 21 to 30 of about 289,598 (269)
Reduced tubulin tyrosination as an early marker of mercury toxicity in differentiating N2a cells [PDF]
, 2007 The aims of this work were to compare the effects of methyl mercury chloride and Thimerosal on neurite/process outgrowth and microtubule proteins in differentiating mouse N2a neuroblastoma and rat C6 glioma cells.
Lawton, M +4 more
core +1 more source
Cells, 2019 Ageing is the result of changes in biochemical and biophysical processes at the cellular level that lead to progressive organ decline. Here we focus on the biophysical changes that impair cellular function of human dermal fibroblasts using donors of ...
Kristina Sliogeryte, Núria Gavara
doaj +1 more source
Pharmaceutics, 2023 A series of novel heterocyclic colchicine derivatives bearing a C-7 methylene fragment were synthesized via Wittig, Horner–Wadsworth–Emmons and Nenajdenko–Shastin olefination approaches.
Iuliia A. Gracheva +5 more
doaj +1 more source
Surface topography of microtubule walls decorated with monomeric and dimeric kinesin constructs [PDF]
, 2000 The surface topography of opened-up microtubule walls (sheets) decorated with monomeric and dimeric kinesin motor domains was investigated by freeze-drying and unidirectional metal shadowing.
Mandelkow, Eckhard +6 more
core +1 more source
Structural state recognition facilitates tip tracking of EB1 at growing microtubule ends
eLife, 2019 The microtubule binding protein EB1 specifically targets the growing ends of microtubules in cells, where EB1 facilitates the interactions of cellular proteins with microtubule plus-ends.
Taylor A Reid +9 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 In this work, we studied an lmna nonsense mutation encoding for the C-terminally truncated Lamin A/C (LMNA) variant Q517X, which was described in patients affected by a severe arrhythmogenic cardiomyopathy with history of sudden death. We found that LMNA
Roberta De Zio +10 more
doaj +1 more source
, 1996 We have studied the self-association reactions of purified GDP-liganded tubulin into double rings and taxoid-induced microtubules, employing synchrotron time-resolved x-ray solution scattering.
Diaz, J.F. +6 more
core +1 more source
Targeting the Achilles Heel of FtsZ: The Interdomain Cleft
Frontiers in Microbiology, 2021 Widespread antimicrobial resistance among bacterial pathogens is a serious threat to public health. Thus, identification of new targets and development of new antibacterial agents are urgently needed. Although cell division is a major driver of bacterial
Pinkilata Pradhan +3 more
doaj +1 more source
Turgor Pressure and Possible Constriction Mechanisms in Bacterial Division
Frontiers in Microbiology, 2018 Bacterial cytokinesis begins with the assembly of FtsZ into a Z ring at the center of the cell. The Z-ring constriction in Gram-negative bacteria may occur in an environment where the periplasm and the cytoplasm are isoosmotic, but in Gram-positive ...
Masaki Osawa, Harold P. Erickson
doaj +1 more source
Frontiers in Immunology, 2022 Vaccination is an effective method to prevent Cryptocaryon irritans infection. Although some vaccines have been developed, large-scale production of these vaccines is costly.
Zequan Mo +9 more
doaj +1 more source