Results 41 to 50 of about 290,382 (301)

Targeting the Achilles Heel of FtsZ: The Interdomain Cleft

open access: yesFrontiers in Microbiology, 2021
Widespread antimicrobial resistance among bacterial pathogens is a serious threat to public health. Thus, identification of new targets and development of new antibacterial agents are urgently needed. Although cell division is a major driver of bacterial
Pinkilata Pradhan   +3 more
doaj   +1 more source

Prevalence of anti-tubulin-α-1c in BD patients and controls. [PDF]

open access: yes, 2018
Prevalence of anti-tubulin-α-1c in BD patients and controls.
Cibo Huang (444680)   +9 more
core   +1 more source

Correlation of serum anti-tubulin-α-1cantibodies with clinical features of RA patients. [PDF]

open access: yes, 2018
Correlation of serum anti-tubulin-α-1cantibodies with clinical features of RA patients.
Cibo Huang (444680)   +9 more
core   +1 more source

Turgor Pressure and Possible Constriction Mechanisms in Bacterial Division

open access: yesFrontiers in Microbiology, 2018
Bacterial cytokinesis begins with the assembly of FtsZ into a Z ring at the center of the cell. The Z-ring constriction in Gram-negative bacteria may occur in an environment where the periplasm and the cytoplasm are isoosmotic, but in Gram-positive ...
Masaki Osawa, Harold P. Erickson
doaj   +1 more source

Protection of Grouper Against Cryptocaryon irritans by Immunization With Tetrahymena thermophila and Protective Cross-Reactive Antigen Identification

open access: yesFrontiers in Immunology, 2022
Vaccination is an effective method to prevent Cryptocaryon irritans infection. Although some vaccines have been developed, large-scale production of these vaccines is costly.
Zequan Mo   +9 more
doaj   +1 more source

Isolation of functional tubulin dimers and of tubulin-associated proteins from mammalian cells [PDF]

open access: yes, 2016
The microtubule (MT) cytoskeleton forms a dynamic filamentous network that is essential for many processes, including mitosis, cell polarity and shape, neurite outgrowth and migration, and ciliogenesis [1, 2]. MTs are built up of α/β-tubulin heterodimers,
Signorile, L.   +20 more
core   +1 more source

Anticancer Activity of Chamaejasmine: Effect on Tubulin Protein

open access: yesMolecules, 2011
In this work, the anticancer activity of chamaejasmine was studied by evaluating its in vitro cytotoxicity against several human cancer cell lines (MCF-7, A549, SGC-7901, HCT-8, HO-4980, Hela, HepG2, PC-3, LNCap, Vero and MDCK) using the MTT assay ...
Yingkun Nie, Wenlong Fang, Songtao Liu
doaj   +1 more source

GSK3 as a Regulator of Cytoskeleton Architecture: Consequences for Health and Disease

open access: yesCells, 2021
Glycogen synthase kinase 3 (GSK3) was initially isolated as a critical protein in energy metabolism. However, subsequent studies indicate that GSK-3 is a multi-tasking kinase that links numerous signaling pathways in a cell and plays a vital role in the ...
Daria Hajka   +5 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Investigating the Specific Interactions Between Microtubule Stabilising Agents and β-Tubulin [PDF]

open access: yes, 2017
Microtubule stabilising agents are a class of cytotoxic compounds that cause mitotic arrest through inhibition of microtubule function. They specifically target β-tubulin subunits promoting tubulin polymerisation, which eventually leads to cell death ...
Jones, Benjamin (11739449)   +1 more
core   +1 more source

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