Results 41 to 50 of about 290,382 (301)
Targeting the Achilles Heel of FtsZ: The Interdomain Cleft
Widespread antimicrobial resistance among bacterial pathogens is a serious threat to public health. Thus, identification of new targets and development of new antibacterial agents are urgently needed. Although cell division is a major driver of bacterial
Pinkilata Pradhan +3 more
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Prevalence of anti-tubulin-α-1c in BD patients and controls. [PDF]
Prevalence of anti-tubulin-α-1c in BD patients and controls.
Cibo Huang (444680) +9 more
core +1 more source
Correlation of serum anti-tubulin-α-1cantibodies with clinical features of RA patients. [PDF]
Correlation of serum anti-tubulin-α-1cantibodies with clinical features of RA patients.
Cibo Huang (444680) +9 more
core +1 more source
Turgor Pressure and Possible Constriction Mechanisms in Bacterial Division
Bacterial cytokinesis begins with the assembly of FtsZ into a Z ring at the center of the cell. The Z-ring constriction in Gram-negative bacteria may occur in an environment where the periplasm and the cytoplasm are isoosmotic, but in Gram-positive ...
Masaki Osawa, Harold P. Erickson
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Vaccination is an effective method to prevent Cryptocaryon irritans infection. Although some vaccines have been developed, large-scale production of these vaccines is costly.
Zequan Mo +9 more
doaj +1 more source
Isolation of functional tubulin dimers and of tubulin-associated proteins from mammalian cells [PDF]
The microtubule (MT) cytoskeleton forms a dynamic filamentous network that is essential for many processes, including mitosis, cell polarity and shape, neurite outgrowth and migration, and ciliogenesis [1, 2]. MTs are built up of α/β-tubulin heterodimers,
Signorile, L. +20 more
core +1 more source
Anticancer Activity of Chamaejasmine: Effect on Tubulin Protein
In this work, the anticancer activity of chamaejasmine was studied by evaluating its in vitro cytotoxicity against several human cancer cell lines (MCF-7, A549, SGC-7901, HCT-8, HO-4980, Hela, HepG2, PC-3, LNCap, Vero and MDCK) using the MTT assay ...
Yingkun Nie, Wenlong Fang, Songtao Liu
doaj +1 more source
GSK3 as a Regulator of Cytoskeleton Architecture: Consequences for Health and Disease
Glycogen synthase kinase 3 (GSK3) was initially isolated as a critical protein in energy metabolism. However, subsequent studies indicate that GSK-3 is a multi-tasking kinase that links numerous signaling pathways in a cell and plays a vital role in the ...
Daria Hajka +5 more
doaj +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Investigating the Specific Interactions Between Microtubule Stabilising Agents and β-Tubulin [PDF]
Microtubule stabilising agents are a class of cytotoxic compounds that cause mitotic arrest through inhibition of microtubule function. They specifically target β-tubulin subunits promoting tubulin polymerisation, which eventually leads to cell death ...
Jones, Benjamin (11739449) +1 more
core +1 more source

