Tumor-Associated Macrophages as Major Immunosuppressive Cells in the Tumor Microenvironment
Within the tumor microenvironment, myeloid cells constitute a dynamic immune population characterized by a heterogeneous phenotype and diverse functional activities. In this review, we consider recent literature shedding light on the increasingly complex
Dipti Athavale +5 more
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Etude des mécanismes cellulaires et moléculaires de la migration des macrophages humains dans des environnements en trois dimensions [PDF]
, 2011 L'infiltration tissulaire des macrophages est un facteur aggravant dans de nombreuses pathologies telles que les maladies inflammatoires chroniques ou le cancer.
Guiet, Romain
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The inflammatory infiltrate of high-grade serous carcinoma omental metastasis [PDF]
, 2014 PhDThe aim of this thesis is to investigate the role of inflammatory infiltrates and chemokines in metastasis of high-grade serous ovarian cancer, HGSC, to the omentum using human tissue biopsies and a 3- dimensional (3D) cell culture model.
Everitt, Gemma Louise Ann
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Corrigendum: Tumor-Associated Macrophages in Tumor Immunity
Frontiers in Immunology, 2021 Yueyun Pan +5 more
doaj +1 more source
Protein‐Nanoarchitectures for Low‐Field Intracellular Electro‐Immunomodulation
Advanced Functional Materials, EarlyView.DHQ‐SDH‐mediated binding of AuNPs drives the formation of interconnected, chain‐like nanoarchitectures with enhanced electrical conductivity. These conductive assemblies undergo macrophage uptake and enable low‐field electrical stimulation, promoting M1‐to‐M2 phenotypic switching with decreased iNOS and increased CD206 expression. Such protein‐mediated
Viktoriya Pakharenko +7 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Nanomedicine engulfed by macrophages for targeted tumor therapy
, 2016 Siwen Li,1,* Song Feng,1,* Li Ding,1 Yuxi Liu,1 Qiuyun Zhu,1 Zhiyu Qian,2 Yueqing Gu1 1Department of Biomedical Engineering, China Pharmaceutical University, 2Department of Biomedical Engineering, School of Automation, Nanjing University of Aeronautics ...
Liu Y +6 more
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Gene Transfer of Calcitonin Gene-Related Peptide Inhibits Macrophages and Inflammatory Mediators in Vein Graft Disease [PDF]
, 2008 Vein graft disease is a chronic inflammatory disease and limits the late results of coronary revascularization. Calcitonin gene-related peptide (CGRP) inhibits macrophages infiltrated and inflammatory mediators, we hypothesized that transfected CGRP gene
Jian Zhuang +8 more
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Tumor-associated macrophages express restricted Ig repertoires.
, 2018 (A) RT-PCR expression profiling of TAM cell preparations for B cell (CD19, CD22), T cell (CD2) and monocyte/ macrophage marker genes (CD14, CD68), respectively, demonstrates absence of detectable quantities of B or T cells.
Tina Fuchs (196304) +11 more
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Tumor-associated macrophages and microglia : double-edged sword in tumor evolvement and invasion
, 2018 Tumor-associated macrophages (TAMs) are among the most abundant cell types in the tumor microenvironment. TAM infiltration is usually linked to tumor progression, metastasis and poor clinical outcome in most human cancers.
Tatjana Wallmann (18677980)
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