Results 121 to 130 of about 115,437 (312)
Tumor-Infiltrating Lymphocytes (TILs) as a Biomarker of Abscopal Effect of Cryoablation in Breast Cancer: A Pilot Study [PDF]
, 2022 Sonia Y. Khan, Michael W. Melkus, Fahmida Rasha, Maribel Castro, Victoria Chu, Luis Brandi, Hafiz Khan, Harvinder Singh Gill, Kevin Pruitt, Rakhshanda Layeequr Rahman +9 moreopenalex +1 more sourceThree‐Year Follow‐Up of Neoadjuvant Tislelizumab with Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Revealing Cancer‐Associated Fibroblast Heterogeneity Corresponding to PD‐1 Blockade Efficacy
Advanced Science, EarlyView.Heterogeneous cancer‐associated fibroblasts orchestrate dual immune microenvironments in LAGC. Abstract
The potential for immunotherapy in patients with locally advanced gastric cancer (LAGC) is recently confirmed. To report the 3‐year follow‐up data are aimed from a novel clinical trial. This is a prospective single‐arm phase II trial.Yao Lin, Xiong Sun, Chengguo Li, Ming Yang, Ke Wu, Ke Liu, Anshu Li, Xiaoming Shuai, Kailin Cai, Zheng Wang, Guobin Wang, Peng Zhang, Jianfeng Shen, Kaixiong Tao, Yuping Yin +14 morewiley +1 more sourceData from An Open-Source, Automated Tumor-Infiltrating Lymphocyte Algorithm for Prognosis in Triple-Negative Breast Cancer
, 2023 Yalai Bai, Kimberly Cole, Sandra Martínez-Morilla, Fahad Shabbir Ahmed, Jon Zugazagoitia, Johan Staaf, Ana Bosch, Anna Ehinger, Emma Niméus, Johan Hartman, Balázs Ács, David L. Rimm +11 moreopenalex +1 more sourceA Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer
Advanced Science, EarlyView.Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...Darbaz Adnan, Natan Roberto de Barros, Luca S. Santovito, Xuhong Cheng, Kristi M. Lawrence, Mariah K. Barnett, Martine D. Boetto, Neal Mehta, Ajaypal Singh, Lin Cheng, Xiangsheng Huang, Faraz Bishehsari +11 morewiley +1 more sourceEngineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy
Advanced Science, EarlyView.IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract
Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang +15 morewiley +1 more sourceSupplementary Figure S11 from Single-cell Profiles and Prognostic Impact of Tumor-Infiltrating Lymphocytes Coexpressing CD39, CD103, and PD-1 in Ovarian Cancer
, 2023 Céline M. Laumont, Maartje C.A. Wouters, Julian Smazynski, Nicole S. Gierc, Elizabeth A. Chavez, Lauren C. Chong, Shelby Thornton, Katy Milne, John R. Webb, Christian Steidl, Brad H. Nelson +10 moreopenalex +1 more sourceImmune Predictors of Radiotherapy Outcomes in Cervical Cancer
Advanced Science, EarlyView.This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen +8 morewiley +1 more sourceCinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU
Advanced Science, EarlyView.Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu +22 morewiley +1 more source94P Diversity of liposarcoma expanded tumor-infiltrating lymphocytes metabolism linked to LAG3 expression [PDF]
Cara Haymaker, J. Oliva Ramirez, Y. Lee, Katarzyna Tomczak, Danh D. Truong, Xiaogen Zhou, Vinod Ravi, Anthony P. Conley, Davis R. Ingram, J. Andrew Livingston, J. Ludwing, Neeta Somaiah +11 moreopenalex +1 more sourceSupplemental Figure 4 from Imaging Tumor-Infiltrating Lymphocytes in Brain Tumors with [<sup>64</sup>Cu]Cu-NOTA-anti-CD8 PET
, 2023 Veronica L. Nagle, Kelly E. Henry, Charli Ann J. Hertz, Maya Srikanth Graham, Carl Campos, Luis F. Parada, Neeta Pandit‐Taskar, Andrea Schietinger, Ingo K. Mellinghoff, Jason S. Lewis +9 moreopenalex +1 more source
