Results 21 to 30 of about 159,317 (346)

Tumor-infiltrating lymphocytes in triple negative breast cancer

open access: yesPatologìâ, 2020
The aim of this retrospective study is to assess the prognostic value of tumor-infiltrating lymphocytes in triple negative breast carcinomas that lack both estrogen, progesterone receptors and Her2 amplification.
L. M. Zakhartseva, M. O. Yanovytska
doaj   +1 more source

Can the plasma PD-1 levels predict the presence and efficiency of tumor-infiltrating lymphocytes in patients with metastatic melanoma? [PDF]

open access: yes, 2019
Background: The immune response in melanoma patients is locally affected by presence of tumor-infiltrating lymphocytes (TILs), generally divided into brisk, nonbrisk, and absent.
Badalamenti G.   +11 more
core   +1 more source

TUMOR-INFILTRATING LYMPHOCYTES IN TRIPLE NEGATIVE BREAST CANCER: CORRELATIVE ANALYSES OF OWN DATA AND LITERATURE REVIEW

open access: yesUkrainian Scientific Medical Youth Journal, 2019
The article summarizes data and presents own study about the value of tumor-infiltrating lymphocytes as a prognostic factor for breast cancer including triple negative breast cancer lacking estrogen and progesterone receptors and HER2\new amplification ...
Liubov Zakhartseva, Mariia Yanovytska
doaj   +1 more source

Tumor-infiltrating T lymphocytes: friends or foes? [PDF]

open access: yesLaboratory Investigation, 2006
The prognostic significance of tumor-infiltrating lymphocytes (TILs) has been a longstanding topic of debate. In cases where TILs have improved patient outcome, T lymphocytes are recognized as the main effectors of antitumor immune responses. However, recent studies have revealed that a subset of CD4(+) T cells, referred to as CD4(+)CD25(+) regulatory ...
Ping Yu, Yang Xin Fu
openaire   +2 more sources

HLA-DR in Cytotoxic T lymphocytes predicts breast cancer patients' response to neoadjuvant chemotherapy [PDF]

open access: yes, 2018
Prediction of breast cancer response to Neoadjuvant Chemotherapy (NACT) is an urgent need to promptly direct non-responder patients to alternative therapies.
Borralho, Paula   +4 more
core   +2 more sources

Dynamics of the intratumoral immune response during progression of high-grade serous ovarian cancer [PDF]

open access: yes, 2018
PURPOSE: Tumor-infiltrating lymphocytes (TILs) have an established impact on the prognosis of high-grade serous ovarian carcinoma (HGSOC), however, their role in recurrent ovarian cancer is largely unknown.
Braicu, I   +18 more
core   +4 more sources

Relevance of tumor-infiltrating lymphocytes in breast cancer [PDF]

open access: yesBMC Medicine, 2015
While breast cancer has not been considered a cancer amenable to immunotherapeutic approaches, recent studies have demonstrated evidence of significant immune cell infiltration via tumor-infiltrating lymphocytes in a subset of patient tumors. In this review we present the current evidence highlighting the clinical relevance and utility of tumor ...
Phillip K. Darcy   +9 more
openaire   +4 more sources

Expression of PD-1 on CD4+ Tumor-Infiltrating Lymphocytes in Tumor Microenvironment Associated with Pathological Characteristics of Breast Cancer

open access: yesJournal of Immunology Research, 2018
Objective. This study aimed to investigate the correlation of CD4+/PD-1+ or CD4+/PD-1− tumor-infiltrating lymphocytes with pathological characteristics in breast cancer patients. Methods.
Yan-Jie Zhao   +10 more
doaj   +1 more source

PD-L1 expression on stromal tumor-infiltrating lymphocytes is a favorable prognostic factor in ovarian serous carcinoma

open access: yesJournal of Ovarian Research, 2019
Background PD-L1 expression levels determined by immunostaining are known to be related to the survival rate and prognosis of patients with various types of cancers, as well as to the therapeutic response to immune checkpoint inhibitors.
Ki Hyung Kim   +7 more
doaj   +1 more source

Association between tumor-infiltrating lymphocytes and sentinel lymph node positivity in thin melanoma [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2019
: Background: Sentinel lymph node biopsy in thin invasive primary cutaneous melanoma (up to 1mm thick) is a controversial subject. The presence of tumor-infiltrating lymphocytes could be a factor to be considered in the decision to perform this ...
Fernando De Marco dos Santos   +5 more
doaj   +1 more source

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