Results 41 to 50 of about 159,317 (346)

Characteristics of lymphocyte-infiltrating papillary thyroid cancer

Journal of Cancer Research and Practice, 2017
Background: The tumor-promoting or tumor-suppressing role of tumor-associated lymphocytes remains a subject of debate. We examined thyroid cancer data from The Cancer Genome Atlas in an attempt to define the relationship between lymphocyte infiltrates ...
Chi-Yu Kuo, Tsang-Pai Liu, Po-Sheng Yang, Shih-Ping Cheng   +3 more
doaj   +1 more source

The prognostic significance of tumor-infiltrating lymphocytes assessment with hematoxylin and eosin sections in resected primary lung adenocarcinoma.

PLoS ONE, 2019
The prognostic significance of tumor-infiltrating lymphocytes has been determined in cancers of the lung, colon and breast, though there is no standardized method for using this prognostic indicator for lung cancer.
Ahrong Kim, So Jeong Lee, Jihyun Ahn, Won Young Park, Dong Hoon Shin, Chang Hun Lee, Hoon Kwon, Yeon Joo Jeong, Hyo Yeong Ahn, Hoseok I, Yeong Dae Kim, Jeong Su Cho   +11 more
doaj   +1 more source

Restoring Lost Anti-HER-2 Th1 Immunity in Breast Cancer: A Crucial Role for Th1 Cytokines in Therapy and Prevention [PDF]

, 2016
The ErbB/B2 (HER-2/neu) oncogene family plays a critical role in the development and metastatic spread of several tumor types including breast, ovarian and gastric cancer.
Czerniecki, Brian J., De La Cruz, Lucy M., Lee, M. Catherine, Nocera, Nadia F., Rosemblit, Cinthia   +4 more
core   +2 more sources

Digital Genomic Quantification of Tumor-Infiltrating Lymphocytes [PDF]

Science Translational Medicine, 2013
A digital DNA-based assay demonstrates an association between higher TIL counts and improved survival among women with ovarian cancer.
Kathy O'Briant, Muneesh Tewari, Nolan G. Ericson, Jamie Guenthoer, Jason H. Bielas, Jason H. Bielas, Harlan Robins, Charles W. Drescher   +7 more
openaire   +3 more sources

Simultaneous analysis of tumor-infiltrating immune cells density, tumor budding status, and presence of lymphoid follicles in CRC tissue

Scientific Reports, 2022
Colorectal cancer (CRC) affects more than 1,000,000 people worldwide each year. Recently, the number of young patients with early-onset colorectal cancer has increased, and right-sided colorectal cancer is still often diagnosed only in advanced stages ...
Adam R. Markowski, Anna J. Markowska, Wiktoria Ustymowicz, Anna Pryczynicz, Katarzyna Guzińska-Ustymowicz   +4 more
doaj   +1 more source

Inhibition of HIF-1 alpha by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma [PDF]

, 2015
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Acland, Assenat, Bazhin, Carbone, Chaput, Chen, Chouaib, Danenberg, David, Dyson, El-Deiry, Gallick, Gelovani, Ghansah, Giese, Gil, Gress, Gribben, Hao, Hao, Hao, Henson, Jemal, Kiessling, Kroemer, Kroemer, Kroemer, Levi, Luo, Mi, Moses, Plate, Powis, Powis, Powis, Ravichandran, Ricci, Rodeck, Sarker, Schuler, Semenza, Singh, Spisek, Tani, Vandenabeele, Wang, Wang, Zitvogel, Zitvogel, Zitvogel   +49 more
core   +1 more source

Tumor-Infiltrating Lymphocytes—Location for Prognostic Evaluation [PDF]

Clinical Cancer Research, 2019
Abstract Tumor-infiltrating lymphocytes (TIL) are crucial for the success of immunotherapy, and their density can predict prognosis. It has now been shown that computer-based analysis of the spatial organization of TILs adds prognostic value in early-stage non–small cell lung cancer, possibly improving the treatment algorithm to prevent ...
Michael Peled, Roy S. Herbst, Amir Onn
openaire   +3 more sources

Tumor-infiltrating γδ T lymphocytes: pathogenic role, clinical significance and differential programming in the tumor microenvironment.

Frontiers in Immunology, 2014
There is increasing clinical evidence indicating that the immune system may either promote or inhibit tumor progression. Several studies have demonstrated that tumors undergoing remission are largely infiltrated by T lymphocytes (tumor-infiltrating ...
Elena eLo Presti, Francesco eDieli, Serena eMeraviglia   +2 more
doaj   +1 more source

Characterizing the immune microenvironment of malignant peripheral nerve sheath tumor by PD-L1 expression and presence of CD8+ tumor infiltrating lymphocytes. [PDF]

, 2016
BackgroundMalignant peripheral nerve sheath tumor (MPNST) is an aggressive sarcoma with few treatment options. Tumor immune state has not been characterized in MPNST, and is important in determining response to immune checkpoint blockade.
Bernthal, Nicholas, Chmielowski, Bartosz, Crompton, Joseph G, Dry, Sarah, Eilber, Fritz C, Federman, Noah, Jensen, Sarah, Li, Yunfeng, Nelson, Scott, Shurell, Elizabeth, Singh, Arun S, Tumeh, Paul   +11 more
core   +2 more sources

Immunology of Tumor Infiltrating Lymphocytes

Annals of Surgery, 1985
Frequently peripheral blood lymphocytes (PBL) do not reflect the tumor host relationship and cell mediated immunity in the PBL does not often correlate with prognosis. The tumor infiltrating lymphocytes (TIL) interact most closely with the tumor cells and are likely to more accurately reflect tumor host interactions.
openaire   +3 more sources