Results 51 to 60 of about 127,911,481 (277)

High-resolution and multi-range particle separation by microscopic vibration in an optofluidic chip

open access: yes, 2017
An optofluidic chip is demonstrated in experiments for high-resolution and multi-range particle separation through the optically-induced microscopic vibration effect, where nanoparticles are trapped in loosely overdamped optical potential wells created ...
Zhang, Jing Bo   +41 more
core   +1 more source

3D cancer models: One step closer to in vitro human studies

open access: yesFrontiers in Immunology, 2023
Cancer immunotherapy is the great breakthrough in cancer treatment as it displayed prolonged progression-free survival over conventional therapies, yet, to date, in only a minority of patients.
Nicoletta Manduca   +5 more
doaj   +1 more source

Engineering Three-Dimensional Tumor Models to Study Glioma Cancer Stem Cells and Tumor Microenvironment

open access: yesFrontiers in Cellular Neuroscience, 2020
Glioblastoma (GBM) is the most common and devastating primary brain tumor, leading to a uniform fatality after diagnosis. A major difficulty in eradicating GBM is the presence of microscopic residual infiltrating disease remaining after multimodality ...
Henry Ruiz-Garcia   +6 more
doaj   +1 more source

In vitro models of breast cancer bone metastasis: analyzing drug resistance through the lens of the microenvironment

open access: yesFrontiers in Oncology, 2023
Even though breast cancers usually have a good outcome compared to other tumors, the cancer can progress and create metastases in different parts of the organism, the bone being a predilection locus.
Anaïs Lamouline   +9 more
doaj   +1 more source

The tooth on-a-chip: a microphysiologic model system mimicking the biologic interface of the tooth with biomaterials

open access: yes, 2020
The tooth has a unique configuration with respect to biomaterials that are used for its treatment. Cells inside of the dental pulp interface indirectly with biomaterials via a calcified permeable membrane, formed by the dentin matrix and several ...
Bertassoni, Luiz E.   +7 more
core   +1 more source

Therapeutic targeting of tumor spheroids in a 3D microphysiological renal cell carcinoma-on-a-chip system

open access: yesNeoplasia, 2023
Metastatic renal cell carcinoma (RCC) remains an incurable disease for most patients highlighting an urgent need for new treatments. However, the preclinical investigation of new therapies is limited by traditional two-dimensional (2D) cultures which do ...
Christopher P. Miller   +6 more
semanticscholar   +1 more source

Scalability of Network-on-Chip communication architecture for 3-D meshes. [PDF]

open access: yes, 2009
Design constraints imposed by global interconnect delays as well as limitations in integration of disparate technologies make 3D chip stacks an enticing technology solution for massively integrated electronic systems.
Awet Yemane Weldezion   +25 more
core   +1 more source

Detection and isolation of circulating tumor cells with single-cell resolution: A successful lab-on-a-chip device [PDF]

open access: yes, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Signorini, G   +7 more
core   +5 more sources

Peristaltic on-chip pump for tunable media circulation and whole blood perfusion in PDMS-free organ-on-chip and Organ-Disc systems

open access: yes, 2022
S.3963-3978Organ-on-chip (OoC) systems have become a promising tool for personalized medicine and drug development with advantages over conventional animal models and cell assays.
Rogal, Julia   +8 more
core   +1 more source

Organ-on-a-Chip Platforms for Drug Screening and Delivery in Tumor Cells: A Systematic Review

open access: yesCancers, 2022
Simple Summary Cancer is one of the diseases with a high mortality rate worldwide. Of the current strategies to study new diagnostic and treating tools, organs-on-chip are quite promising regarding the achievement of more personalized medicine.
I. Gonçalves   +9 more
semanticscholar   +1 more source

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