Results 61 to 70 of about 138,643 (133)

A vascularized tumors-on-a-chip model for studying tumor-angiogenesis interplay, heterogeneity and drug responses

Materials Today Bio
Current tumor models struggle to replicate the complexity of the tumor microenvironment, particularly endothelial sprouting and vascular-tumor interactions.
Suyeon Shin, Yurim Choi, WonJun Jang, Batjargal Ulziituya, Giheon Ha, Raehui Kang, Soojin Park, Minseok Kim, Yu Shrike Zhang, Han-Jun Kim, Junmin Lee   +10 more
doaj   +1 more source

A smart procedure for the femtosecond laser-based fabrication of a polymeric lab-on-a-chip for capturing tumor cell

, 2020
Rapid prototyping methods for the design and fabrication of polymeric labs-on-a-chip are on the rise, as they allow high degrees of precision and flexibility.
Annalisa Volpe, U. Krishnan, M. Chiriacò, E. Primiceri, A. Ancona, F. Ferrara   +5 more
semanticscholar   +1 more source

Microfluidic chips for decoding cancer-immune crosstalk in immunotherapy

Frontiers in Immunology
The crosstalk between cancer cells and the immune system within the tumor microenvironment (TME) governs the efficacy of immunotherapeutic interventions.
Xianlei Cai, Xia Xiao, Congcong Zhang, Weiming Yu   +3 more
doaj   +1 more source

Microfluidics-Based Technologies for the Assessment of Castration-Resistant Prostate Cancer

Cells
Castration-resistant prostate cancer remains a significant clinical challenge, wherein patients display no response to existing hormone therapies. The standard of care often includes aggressive treatment options using chemotherapy, radiation therapy and ...
Amel Sassi, Lidan You
doaj   +1 more source

Host-microbe-cancer interactions on-a-chip

Frontiers in Bioengineering and Biotechnology
The tumor microbiota has emerged as a pivotal contributor to a variety of cancers, impacting disease development, progression, and therapeutic resistance.
Mauricio G. C. Sousa, Mauricio G. C. Sousa, Mauricio G. C. Sousa, Danielle S. K. Brasino, Madeline Krieger, Duygu A. Dindar, Rebekka Duhen, Rebekka Duhen, Zhenzhen Zhang, Cristiane Miranda Franca, Cristiane Miranda Franca, Cristiane Miranda Franca, Luiz E. Bertassoni, Luiz E. Bertassoni, Luiz E. Bertassoni, Luiz E. Bertassoni, Luiz E. Bertassoni   +16 more
doaj   +1 more source

Advances in engineering immune–tumor microenvironments on-a-chip: integrative microfluidic platforms for immunotherapy and drug discovery

Molecular Cancer
The design and application of microfluidic immune system-on-a-chip (ISOC) technology have played a critical role in cancer immunology and drug discovery over the past decades.
Farnaz Dabbagh Moghaddam, A. Anvar, Ehsan Ilkhani, Delara Dadgar, Maedeh Rafiee, Najmeh Ranjbaran, Pejman Mortazavi, S. M. Ghoreishian, Yun Suk Huh, Pooyan Makvandi   +9 more
semanticscholar   +1 more source

A 3D Human Renal Cell Carcinoma-on-a-Chip for the Study of Tumor Angiogenesis1

Neoplasia, 2018
Tractable human tissue-engineered 3D models of cancer that enable fine control of tumor growth, metabolism, and reciprocal interactions between different cell types in the tumor microenvironment promise to accelerate cancer research and pharmacologic ...
Chris P. Miller, Connor A. Tsuchida, Ying Zheng, J. Himmelfarb, Shreeram Akilesh   +4 more
semanticscholar   +1 more source

Controllable Histotomy Based on Hierarchical Magnetic Microneedle Array Robots

Engineering
Investigation of patient-derived primary tissues is of great importance in the biomedical field, but recent tissue slicing and cultivation techniques still have difficulties in satisfying clinical requirements.
Xiaoxuan Zhang, Hanxu Chen, Taiyu Song, Jinglin Wang, Yuanjin Zhao   +4 more
doaj   +1 more source

Liquid Biopsy in Colorectal Cancer-Current Status and Potential Clinical Applications

Micromachines, 2018
Colorectal cancer is one of the most frequent solid malignancies worldwide. The treatment is either surgical or multimodal and depends on the stage of the disease at diagnosis. Accurate disease assessment is thus of great importance for choosing the most
Gregor Norcic
doaj   +1 more source

Vascularized tumor on a microfluidic chip to study mechanisms promoting tumor neovascularization and vascular targeted therapies

Theranostics
The cascade of events leading to tumor formation includes induction of a tumor supporting neovasculature, as a primary hallmark of cancer. Developing vasculature is difficult to evaluate in vivo but can be captured using microfluidic chip technology and ...
Magdalena Skubal, B. M. Larney, N. Phung, Juan Carlos Desmaras, A. Dozic, Alessia Volpe, Anuja Ogirala, Camila Longo Machado, Jakob Djibankov, V. Ponomarev, J. Grimm   +10 more
semanticscholar   +1 more source