Results 61 to 70 of about 127,911,481 (277)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
3D Inkjet-Bioprinted Lung-on-a-Chip
, 2023 There is an urgent need for physiologically relevant and customizable biochip models of human lung tissue to provide a niche for lung disease modeling and drug efficacy.
Dayoon Kang +11 more
core +1 more source
Molecules, 2021 To study the simultaneous effect of the molecular gradient of polyphenols (curcumin, trans-resveratrol, and wogonin) and biological factors released from tumor cells on apoptosis of adjacent cells, a novel microfluidic system was designed and ...
Roman G. Szafran +2 more
doaj +1 more source
Lab on a ChipThe development of effective cancer therapies remains constrained by the complex and dynamic nature of the tumor microenvironment (TME), with tumor vasculature representing a critical barrier and modulator of treatment response.
Ines Poljak +2 more
semanticscholar +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Lab-on-a-chip and integrated strategies in tumor immunotheraphy [PDF]
, 2011 Background While conventional chemotherapy and radiation therapy have improved the survival of many cancer patients, there are still major disadvantages associated with these treatments such as high toxicity and drug-resistance.
Destro, Federica
core
Correction: 3D printed nervous system on a chip
, 2016 Correction for ‘3D printed nervous system on a chip’ by Blake N.
Meng, Fanben +6 more
core +1 more source
Rapid determination of vitamin B12 concentration with a chemiluminescence lab on a chip [PDF]
, 2012 This paper reports a novel method for the rapid determination of vitamin B12 concentration in a continuous-flow lab-on-a-chip system. This new method is based on luminol-peroxide chemiluminescence (CL) assays for the detection of cobalt(II) ions in ...
Nguyen, Nam-Trung +7 more
core +1 more source
Different Microfluidic Environments for In Vitro Testing of Lipid Nanoparticles against Osteosarcoma
Bioengineering, 2021 The use of lipid nanoparticles as biodegradable shells for controlled drug delivery shows promise as a more effective and targeted tumor treatment than traditional treatment methods.
Oihane Mitxelena-Iribarren +4 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source