Results 41 to 50 of about 127,911,481 (277)

Fast electrically assisted regeneration of on-chip SERS substrates

, 2022
S.2923-2927A microfluidic chip approach utilising integrated electrically connected stationary SERS targets based on inkjet-printed silver nanoparticles is presented.
Belder, Detlev, Kemper, F., Poehler, Elisabeth, Pabst, Oliver, Jahnke, Heinz-Georg, Beckert, Erik, Robitzki, Andrea Anneliese, Meier, T.-A.   +7 more
core   +1 more source

Three-Dimensional In Vitro Lymphangiogenesis Model in Tumor Microenvironment

Frontiers in Bioengineering and Biotechnology, 2021
Lymphangiogenesis is a stage of new lymphatic vessel formation in development and pathology, such as inflammation and tumor metastasis. Physiologically relevant models of lymphatic vessels have been in demand because studies on lymphatic vessels are ...
Youngkyu Cho, Youngkyu Cho, Kyuhwan Na, Yesl Jun, Yesl Jun, Jihee Won, Ji Hun Yang, Ji Hun Yang, Seok Chung, Seok Chung   +9 more
doaj   +1 more source

Tumor-on-a-chip platforms to study cancer-immune system crosstalk in the era of immunotherapy.

Lab on a Chip, 2020
Immunotherapy is a powerful therapeutic approach able to re-educate the immune system to fight cancer. A key player in this process is the tumor microenvironment (TME), which is a dynamic entity characterized by a complex array of tumor and stromal cells
S. Parlato, Giulia Grisanti, G. Sinibaldi, G. Peruzzi, C. Casciola, L. Gabriele   +5 more
semanticscholar   +1 more source

Low-cost on-chip clock jitter measurement scheme [PDF]

, 2014
In this paper, we present a low-cost, on-chip clock jitter digital measurement scheme for high performance microprocessors. It enables in situ jitter measurement during the test or debug phase.
Giaffreda, Daniele, Rahman A., Omana, Martin, Rossi D., Tam, S., Omana M., Omana, M., Metra C., Metra, C., Mak, TM, Rahman, A., Rossi, Daniele, S. Tam, Giaffreda, D., Metra, Cecilia, Raman, Asifur, A. Rahman, Mak, T.M., Mak T. M., D. Giaffreda, TM Mak, Giaffreda D., Tam, Simon, Tam S., OMANA, MARTIN EUGENIO, Rossi, D.   +25 more
core   +1 more source

A microvessel-on-a-chip for studying how tumor-derived factors prime the endothelium for extravasation

, 2023
Slater, John H.Metastasis is a leading cause of disability and death from cancer. Each year, 50% of new cancer patients are diagnosed with metastasis and must undergo immediate and aggressive treatment.
Sperduto, John Lewis
core   +1 more source

An in vitro model of cancer invasion with heterogeneous ECM created with droplet microfluidics

Frontiers in Bioengineering and Biotechnology, 2023
Metastasis is a multi-step process that is critically affected by cues from the tumor micro-environment (TME), such as from the extracellular matrix (ECM). The role of the ECM in the onset of metastasis, invasion, is not yet fully understood.
Mohammad Jouybar, Mohammad Jouybar, Jelle J. F. Sleeboom, Jelle J. F. Sleeboom, Jelle J. F. Sleeboom, Elnaz Vaezzadeh, Cecilia M. Sahlgren, Cecilia M. Sahlgren, Cecilia M. Sahlgren, Jaap M. J. den Toonder, Jaap M. J. den Toonder   +10 more
doaj   +1 more source

Metastasis in context: modeling the tumor microenvironment with cancer-on-a-chip approaches

Disease Models & Mechanisms, 2018
Most cancer deaths are not caused by the primary tumor, but by secondary tumors formed through metastasis, a complex and poorly understood process.
Jelle J. F. Sleeboom, Hossein Eslami Amirabadi, Poornima Nair, Cecilia M. Sahlgren, Jaap M. J. den Toonder   +4 more
doaj   +1 more source

Tumor-on-a-chip platform to investigate progression and drug sensitivity in cell lines and patient-derived organoids

Lab on a Chip, 2018
Most cancer treatment strategies target cell proliferation, angiogenesis, migration, and intravasation of tumor cells in an attempt to limit tumor growth and metastasis.
V. Shirure, Y. Bi, M. Curtis, Andrew Lezia, Madeleine Goedegebuure, S. Goedegebuure, R. Aft, R. Fields, Steven C. George   +8 more
semanticscholar   +1 more source

Gradient-sized control of tumor spheroids on a single chip.

, 2020
Multicellular tumor spheroids are attracting more attention as a physiologically relevant in vitro tumor model for biomedical research. The size of spheroids is one of the critical parameters related to drug penetration and cellular responses. It remains
Gallego-Ortega, D, Jin, D, Law, A, Fang, G, Lin, G, Lu, H   +5 more
core   +1 more source

Integrating biological vasculature into a multi-organ-chip microsystem

, 2022
S.3588-3598A chip-based system mimicking the transport function of the human cardiovascular system has been established at minute but standardized microsystem scale.
Lindner, G., Sonntag, F., Menzel, U., Marx, U., Groth, B., Horland, R., Lauster, R., Hoffmann, S., Walles, Heike, Lorenz, A., Schimek, K., Busek, M., Brincker, S.   +12 more
core   +1 more source