Results 41 to 50 of about 91,694,512 (315)

Imaging Diffusion and Stability of Single‐Chain Polymeric Nanoparticles in a Multi‐Gel Tumor‐on‐a‐Chip Microfluidic Device [PDF]

The performance of single-chain polymeric nanoparticles (SCPNs) in biomedical applications highly depends on their conformational stability in cellular environments.
Linlin Deng, Alis R. Olea, Ana Ortiz‐Perez, Bingbing Sun, Jianhong Wang, Sílvia Pujals, Anja R. A. Palmans, Lorenzo Albertazzi   +7 more
openalex   +3 more sources

Chemotaxis-driven assembly of endothelial barrier in a tumor-on-a-chip platform [PDF]

Lab on a Chip, 2016
Chemotaxis-driven assembly of an endothelial barrier around tumor cells within a microfluidics device.
Aereas, Aung, Jomkuan, Theprungsirikul, Han Liang, Lim, Shyni, Varghese   +3 more
openaire   +2 more sources

3D Tumor Models and Their Use for the Testing of Immunotherapies

Frontiers in Immunology, 2020
Over the past decade, immunotherapy has become a powerful and evident tool in the fight against cancers. Notably, the rise of checkpoint blockade using monoclonal antibodies (anti-CTLA4, anti-PD1) to avoid interaction between inhibitory molecules allowed
Nicolas Boucherit, Laurent Gorvel, Daniel Olive   +2 more
doaj   +1 more source

Advances in analytical microfluidic workflows for differential cancer diagnosis

Nano Select, 2023
Early detection and functional analysis of circulating tumor cells (CTCs) in liquid biopsy rather than counting them offer great promise as physicians can improve differential diagnosis for second‐ or third‐line treatment beyond today's genotype ...
Morteza Hasanzadeh Kafshgari, Oliver Hayden   +1 more
doaj   +1 more source

Dissecting the immunosuppressive tumor microenvironments in Glioblastoma-on-a-Chip for optimized PD-1 immunotherapy

eLife, 2020
Programmed cell death protein-1 (PD-1) checkpoint immunotherapy efficacy remains unpredictable in glioblastoma (GBM) patients due to the genetic heterogeneity and immunosuppressive tumor microenvironments.
Xin Cui, Chao Ma, Varshini Vasudevaraja, Jonathan Serrano, Jie Tong, Yansong Peng, Michael Delorenzo, Guomiao Shen, Joshua Frenster, Renee-Tyler Tan Morales, Weiyi Qian, Aristotelis Tsirigos, Andrew S Chi, Rajan Jain, Sylvia C Kurz, Erik P Sulman, Dimitris G Placantonakis, Matija Snuderl, Weiqiang Chen   +18 more
doaj   +1 more source

Microfluidic Platforms for High-Throughput Pancreatic Ductal Adenocarcinoma Organoid Culture and Drug Screening

Frontiers in Cell and Developmental Biology, 2021
Pancreatic Ductal Adenocarcinoma (PDAC), the most common pancreatic cancer type, is believed to become the second leading cause of cancer-related deaths by 2030 with mortality rates of up to 93%.
Marlene Geyer, Karla Queiroz
doaj   +1 more source

A heterotypic tumor-on-a-chip platform for user-friendly combinatorial chemotherapeutic testing

Analytica Chimica Acta
Three-dimensional (3D) tumor microdevices are promising platform for biomimetic antitumor prediction and high-throughput chemotherapeutic screening and play crucial roles in the exploration of cancer-associated pharmaceutics and therapeutics. Traditional cell manipulation tools (e.g., non-adhesive surfaces and hanging drops) and recent microengineered ...
Xufang Liu, Meilin Sun, Fen Zhang, Jinwei Zhang, Tingting Xuanyuan, Wenming Liu   +5 more
openalex   +3 more sources

Three-Dimensional In Vitro Lymphangiogenesis Model in Tumor Microenvironment

Frontiers in Bioengineering and Biotechnology, 2021
Lymphangiogenesis is a stage of new lymphatic vessel formation in development and pathology, such as inflammation and tumor metastasis. Physiologically relevant models of lymphatic vessels have been in demand because studies on lymphatic vessels are ...
Youngkyu Cho, Youngkyu Cho, Kyuhwan Na, Yesl Jun, Yesl Jun, Jihee Won, Ji Hun Yang, Ji Hun Yang, Seok Chung, Seok Chung   +9 more
doaj   +1 more source

Low-cost on-chip clock jitter measurement scheme [PDF]

, 2014
In this paper, we present a low-cost, on-chip clock jitter digital measurement scheme for high performance microprocessors. It enables in situ jitter measurement during the test or debug phase.
Giaffreda, Daniele, Rahman A., Omana, Martin, Rossi D., Tam, S., Omana M., Omana, M., Metra C., Metra, C., Mak, TM, Rahman, A., Rossi, Daniele, S. Tam, Giaffreda, D., Metra, Cecilia, Raman, Asifur, A. Rahman, Mak, T.M., Mak T. M., D. Giaffreda, TM Mak, Giaffreda D., Tam, Simon, Tam S., OMANA, MARTIN EUGENIO, Rossi, D.   +25 more
core   +1 more source

Fast electrically assisted regeneration of on-chip SERS substrates

, 2022
S.2923-2927A microfluidic chip approach utilising integrated electrically connected stationary SERS targets based on inkjet-printed silver nanoparticles is presented.
Belder, Detlev, Kemper, F., Poehler, Elisabeth, Pabst, Oliver, Jahnke, Heinz-Georg, Beckert, Erik, Robitzki, Andrea Anneliese, Meier, T.-A.   +7 more
core   +1 more source