Results 21 to 30 of about 138,643 (133)
Spatiotemporal dissection of tumor microenvironment via in situ sensing and monitoring in tumor-on-a-chip [PDF]
Biosensors and Bioelectronics, 2023 Lang Zhou, Weiqiang Chen, Pengyu Chen
exaly +2 more sources
Cell Reports, 2018 Summary: A major challenge in cancer research is the complexity of the tumor microenvironment, which includes the host immunological setting. Inspired by the emerging technology of organ-on-chip, we achieved 3D co-cultures in microfluidic devices ...
Marie Nguyen +22 more
doaj +3 more sources
Tumor Microenvironment on a Chip: The Progress and Future Perspective
Bioengineering, 2017 Tumors develop in intricate microenvironments required for their sustained growth, invasion, and metastasis. The tumor microenvironment plays a critical role in the malignant or drug resistant nature of tumors, becoming a promising therapeutic target ...
Jungho Ahn +3 more
doaj +3 more sources
A Hybrid In Silico and Tumor-on-a-Chip Approach to Model Targeted Protein Behavior in 3D Microenvironments [PDF]
Cancers, 2021 Valentina Palacio-Castañeda +2 more
exaly +2 more sources
Micromachines, 2021 Glioma, as an aggressive type of cancer, accounts for virtually 80% of malignant brain tumors. Despite advances in therapeutic approaches, the long-term survival of glioma patients is poor (it is usually fatal within 12–14 months).
Merve Ustun +4 more
doaj +1 more source
Engineered Vasculature for Organ-on-a-Chip Systems
Engineering, 2022 Organ-on-a-chip technology, a promising three-dimensional (3D) dynamic culture method, ensures accurate and efficient cell culture and has great potential for replacing animal models in preclinical testing. The circulatory system, the most abundant organ
Abdellah Aazmi +8 more
doaj +1 more source
Organ-on-a-chip Technology in Urology
Креативная хирургия и онкология, 2023 Organs-on-chips (OOC) refer to microfluidic devices used to create biomimetic systems of physiological organs. The system contains engineered or natural miniature tissues grown inside microfluidic chips.
A. G. Vardikian +4 more
doaj +1 more source
27 Defining elite macrophages from tumor-on-a-chip
Journal for ImmunoTherapy of Cancer, 2023 Yang Xiang, Xiaohan Feng
doaj +2 more sources
Analysis of Static Molecular Gradients in a High-Throughput Drug Screening Microfluidic Assay
Molecules, 2021 In this study, we thoroughly analyzed molecular gradient generation, its stability over time, and linearity in our high-throughput drug screening microfluidic assay (HTS).
Roman G. Szafran, Benita Wiatrak
doaj +1 more source
Recapitulating Solid Stress on Tumor on a Chip for Nanomedicine Diffusive Transport Prediction
Advanced NanoBiomed Research, 2023 The characteristic mechanical forces at play within tumors include the abnormal solid and fluid stresses. These, together with the increased extracellular matrix (ECM) stiffness, are the major transport barriers affecting the nanomedicine delivery to ...
Alberto Martín-Asensio +8 more
doaj +1 more source