Results 31 to 40 of about 91,694,512 (315)
Mechanical cues in tumor microenvironment on chip
Biosensors and Bioelectronics: X, 2023 Mechanical cues from the tumor microenvironment (TME) can influence cell behaviors and have been indicated to play a pivotal role in tumor initiation, progression, and metastasis. The integration of microfluidics technologies, bioelectronics, and tissue engineering approaches have allowed the development of various in-vitro TME on-chip models.
Zhiru Zhou +5 more
openaire +2 more sources
From chip-in-a-lab to lab-on-a-chip: towards a single handheld electronic system for multiple application-specific lab-on-a-chip (ASLOC) [PDF]
, 2020 We present a portable, battery-operated and application-specific lab-on-a-chip (ASLOC) system that can be easily configured for a wide range of lab-on-a-chip applications. It is based on multiplexed electrical current detection that serves as the sensing
Campos, C. D. M. +5 more
core +2 more sources
Analysis of Static Molecular Gradients in a High-Throughput Drug Screening Microfluidic Assay
Molecules, 2021 In this study, we thoroughly analyzed molecular gradient generation, its stability over time, and linearity in our high-throughput drug screening microfluidic assay (HTS).
Roman G. Szafran, Benita Wiatrak
doaj +1 more source
Multimodal profiling of CAR T cells against glioblastoma using a microengineered 3D tumor-on-a-chip model [PDF]
Bioact MaterKalpana Ravi +6 more
openalex +2 more sources
Nano Convergence, 2021 Recent developments of organoids engineering and organ-on-a-chip microfluidic technologies have enabled the recapitulation of the major functions and architectures of microscale human tissue, including tumor pathophysiology.
Jungeun Lim +4 more
doaj +1 more source
Recent Advances of Organ-on-a-Chip in Cancer Modeling Research
Biosensors, 2022 Although many studies have focused on oncology and therapeutics in cancer, cancer remains one of the leading causes of death worldwide. Due to the unclear molecular mechanism and complex in vivo microenvironment of tumors, it is challenging to reveal the
Xingxing Liu +10 more
doaj +1 more source
Research progress and future perspectives of tumor organoid [PDF]
Zhongguo aizheng zazhiTumor organoids, derived from tumor tissues, are three-dimensional structures created in vitro to mimic in vivo tumor growth. They possess comparable genetic lineage and pathological characteristics to the original tumor, making them a promising research
XIAO Yi, WU Ming, YAO Gang
doaj +3 more sources
27 Defining elite macrophages from tumor-on-a-chip
Journal for ImmunoTherapy of Cancer, 2023 Yang Xiang, Xiaohan Feng
doaj +2 more sources
, 2022 Malignant cells grow in a complex microenvironment that plays a key role in cancer progression. The "dynamic reciprocity" existing between cancer cells and their microenvironment is involved in cancer differentiation, proliferation, invasion, metastasis,
Imparato, Giorgia +3 more
core +1 more source
Applications of Microfluidics and Organ-on-a-Chip in Cancer Research
Biosensors, 2022 Taking the life of nearly 10 million people annually, cancer has become one of the major causes of mortality worldwide and a hot topic for researchers to find innovative approaches to demystify the disease and drug development.
Sagar Regmi +3 more
doaj +1 more source