Results 31 to 40 of about 138,643 (133)
Tumor-on-a-chip platform to interrogate the role of macrophages in tumor progression [PDF]
Integrative Biology (United Kingdom), 2020 Ryan Fields +2 more
exaly +2 more sources
Nano Convergence, 2021 Recent developments of organoids engineering and organ-on-a-chip microfluidic technologies have enabled the recapitulation of the major functions and architectures of microscale human tissue, including tumor pathophysiology.
Jungeun Lim +4 more
doaj +1 more source
Recent Advances of Organ-on-a-Chip in Cancer Modeling Research
Biosensors, 2022 Although many studies have focused on oncology and therapeutics in cancer, cancer remains one of the leading causes of death worldwide. Due to the unclear molecular mechanism and complex in vivo microenvironment of tumors, it is challenging to reveal the
Xingxing Liu +10 more
doaj +1 more source
Research progress and future perspectives of tumor organoid [PDF]
Zhongguo aizheng zazhiTumor organoids, derived from tumor tissues, are three-dimensional structures created in vitro to mimic in vivo tumor growth. They possess comparable genetic lineage and pathological characteristics to the original tumor, making them a promising research
XIAO Yi, WU Ming, YAO Gang
doaj +3 more sources
Applications of Microfluidics and Organ-on-a-Chip in Cancer Research
Biosensors, 2022 Taking the life of nearly 10 million people annually, cancer has become one of the major causes of mortality worldwide and a hot topic for researchers to find innovative approaches to demystify the disease and drug development.
Sagar Regmi +3 more
doaj +1 more source
3D Tumor Models and Their Use for the Testing of Immunotherapies
Frontiers in Immunology, 2020 Over the past decade, immunotherapy has become a powerful and evident tool in the fight against cancers. Notably, the rise of checkpoint blockade using monoclonal antibodies (anti-CTLA4, anti-PD1) to avoid interaction between inhibitory molecules allowed
Nicolas Boucherit +2 more
doaj +1 more source
Advances in analytical microfluidic workflows for differential cancer diagnosis
Nano Select, 2023 Early detection and functional analysis of circulating tumor cells (CTCs) in liquid biopsy rather than counting them offer great promise as physicians can improve differential diagnosis for second‐ or third‐line treatment beyond today's genotype ...
Morteza Hasanzadeh Kafshgari +1 more
doaj +1 more source
eLife, 2020 Programmed cell death protein-1 (PD-1) checkpoint immunotherapy efficacy remains unpredictable in glioblastoma (GBM) patients due to the genetic heterogeneity and immunosuppressive tumor microenvironments.
Xin Cui +18 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Pancreatic Ductal Adenocarcinoma (PDAC), the most common pancreatic cancer type, is believed to become the second leading cause of cancer-related deaths by 2030 with mortality rates of up to 93%.
Marlene Geyer, Karla Queiroz
doaj +1 more source
Tumor-on-a-chip platforms to study cancer-immune system crosstalk in the era of immunotherapy.
Lab on a Chip, 2020 Immunotherapy is a powerful therapeutic approach able to re-educate the immune system to fight cancer. A key player in this process is the tumor microenvironment (TME), which is a dynamic entity characterized by a complex array of tumor and stromal cells
S. Parlato +5 more
semanticscholar +1 more source