Results 11 to 20 of about 3,620,379 (402)
The tumor microenvironment [PDF]
Indian Journal of Medical and Paediatric Oncology, 2020 A tumor is not simply a group of cancer cells, but rather a heterogeneous collection of infiltrating and resident host cells, secreted factors and extracellular matrix.
A. Rasheed, V. Koyyala
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Hypoxia and the Tumor Microenvironment [PDF]
Technology in Cancer Research & Treatment, 2021 Hypoxia is an important feature of the tumor microenvironment, and is closely associated with cell proliferation, angiogenesis, metabolism and the tumor immune response. All these factors can further promote tumor progression, increase tumor aggressiveness, enhance tumor metastatic potential and lead to poor prognosis. In this review, these effects of
Li Xiaofeng +4 more
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Medicina, 2019 Background and Objectives: The tumor microenvironment has been widely implicated in tumorigenesis because it harbors tumor cells that interact with surrounding cells through the circulatory and lymphatic systems to influence the development and progression of cancer.
Arneth, Borros +1 more
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S-Nitrosylation in Tumor Microenvironment [PDF]
International Journal of Molecular Sciences, 2021 S-nitrosylation is a selective and reversible post-translational modification of protein thiols by nitric oxide (NO), which is a bioactive signaling molecule, to exert a variety of effects. These effects include the modulation of protein conformation, activity, stability, and protein-protein interactions.
Vandana Sharma +6 more
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Cell Communication and Signaling, 2020 Background Metabolic reprogramming contributes significantly to tumor development and is tightly linked to drug resistance. The chemotherapeutic agent etoposide (VP-16) has been used clinically in the treatment of lung cancer but possess different ...
Qi Dong +14 more
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Biochanin A inhibits lung adenocarcinoma progression by targeting ZEB1
Discover Oncology, 2022 Lung adenocarcinoma is the major subtype of lung cancer, accounting for approximately 40% of lung cancers. During clinical treatment, the emergence of chemotherapy resistance seriously affects the effectiveness of treatment.
Jianjun Li +12 more
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Tumor microenvironment signaling and therapeutics in cancer progression
Cancer Communications, 2023 Tumor development and metastasis are facilitated by the complex interactions between cancer cells and their microenvironment, which comprises stromal cells and extracellular matrix (ECM) components, among other factors.
A. Goenka +7 more
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T cells in tumor microenvironment [PDF]
Tumor Biology, 2015 Tumors progress in a specific area, which supports its development, spreading or shrinking in time with the presence of different factors that effect the fate of the cancer cells. This specialized site is called "tumor microenvironment" and has a composition of heterogenous materials.
Yağmur Kiraz +4 more
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Crosstalk of Inflammatory Cytokines within the Breast Tumor Microenvironment
International Journal of Molecular Sciences, 2023 Several immune and immunocompetent cells, including dendritic cells, macrophages, adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the complex discipline of oncology. Cytotoxic innate and adaptive immune cells can
O. Habanjar +5 more
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Tumor microenvironment and radioresistance [PDF]
Experimental & Molecular Medicine, 2021 AbstractMetastasis is not the result of a random event, as cancer cells can sustain and proliferate actively only in a suitable tissue microenvironment and then form metastases. Since Dr. Stephen Paget in the United Kingdom proposed the seed and soil hypothesis of cancer metastasis based on the analogy that plant seeds germinate and grow only in ...
Minoru Kobayashi +3 more
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