Results 11 to 20 of about 3,561,070 (402)
The tumor microenvironment [PDF]
Indian Journal of Medical and Paediatric Oncology, 2020 A tumor is not simply a group of cancer cells, but rather a heterogeneous collection of infiltrating and resident host cells, secreted factors and extracellular matrix.
A. Rasheed, V. Koyyala
semanticscholar +5 more sources
Understanding the tumor immune microenvironment (TIME) for effective therapy
Nature Medicine, 2018 Vincent Chan +2 more
exaly +2 more sources
Nonlinear simulation of the effect of microenvironment on tumor growth [PDF]
, 2006 Paul Macklin, John Lowengrub
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Hypoxia and the Tumor Microenvironment [PDF]
Technology in Cancer Research & Treatment, 2021 Hypoxia is an important feature of the tumor microenvironment, and is closely associated with cell proliferation, angiogenesis, metabolism and the tumor immune response. All these factors can further promote tumor progression, increase tumor aggressiveness, enhance tumor metastatic potential and lead to poor prognosis. In this review, these effects of
Li Xiaofeng +4 more
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Molecular Cancer, 2021 Cancer-associated fibroblasts (CAFs), a stromal cell population with cell-of-origin, phenotypic and functional heterogeneity, are the most essential components of the tumor microenvironment (TME).
Xiaoqi Mao +9 more
semanticscholar +1 more source
Cell Death Discovery, 2023 Ferroptosis is a newly defined non-apoptotic programmed cell death resulting from the accumulation of lipid peroxides. Whether ferroptosis plays any role in chemotherapy remains to be established.
Feng Cheng +8 more
doaj +1 more source
Role of tumor microenvironment in cancer progression and therapeutic strategy
Cancer Medicine, 2023 Cancer is now considered a tumor microenvironment (TME) disease, although it was originally thought to be a cell and gene expression disorder. Over the past 20 years, significant advances have been made in understanding the complexity of the TME and its ...
Qingjing Wang +8 more
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Medicina, 2019 Background and Objectives: The tumor microenvironment has been widely implicated in tumorigenesis because it harbors tumor cells that interact with surrounding cells through the circulatory and lymphatic systems to influence the development and progression of cancer.
Arneth, Borros +1 more
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Molecular Cancer, 2023 Despite centuries since the discovery and study of cancer, cancer is still a lethal and intractable health issue worldwide. Cancer-associated fibroblasts (CAFs) have gained much attention as a pivotal component of the tumor microenvironment.
Hao Zhang +11 more
semanticscholar +1 more source
Lipid metabolic reprogramming in tumor microenvironment: from mechanisms to therapeutics
Journal of Hematology & Oncology, 2023 Lipid metabolic reprogramming is an emerging hallmark of cancer. In order to sustain uncontrolled proliferation and survive in unfavorable environments that lack oxygen and nutrients, tumor cells undergo metabolic transformations to exploit various ways ...
Haoran Jin +6 more
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