Results 31 to 40 of about 512,927 (317)
Glycocalyx Acts as a Central Player in the Development of Tumor Microenvironment by Extracellular Vesicles for Angiogenesis and Metastasis [PDF]
, 2022 Angiogenesis in tumor growth and progression involves a series of complex changes in the tumor microenvironment. Extracellular vesicles (EVs) are important components of the tumor microenvironment, which can be classified as exosomes, apoptotic vesicles,
Zeng, Ye +7 more
core +1 more source
Intratumoral Platelets: Harmful or Incidental Bystanders of the Tumor Microenvironment? [PDF]
, 2022 SIMPLE SUMMARY: The tumor microenvironment (TME) is the complex and heterogenous ecosystem of solid tumors known to influence their growth and their progression.
Le Chapelain, Ophélie +3 more
core +1 more source
Efferocytosis in the tumor microenvironment [PDF]
Seminars in Immunopathology, 2018 Within the course of a single minute, millions of cells in the human body will undergo programmed cell death in response to physiological or pathological cues. The diminished energetic capacity of an apoptotic cell renders the cell incapable of sustaining plasma membrane integrity.
Werfel, Thomas A., Cook, Rebecca S.
openaire +2 more sources
MRI of the tumor microenvironment [PDF]
Journal of Magnetic Resonance Imaging, 2002 AbstractThe microenvironment within tumors is significantly different from that in normal tissues. A major difference is seen in the chaotic vasculature of tumors, which results in unbalanced blood supply and significant perfusion heterogeneities. As a consequence, many regions within tumors are transiently or chronically hypoxic.
Robert J, Gillies +3 more
openaire +2 more sources
Tumor Microenvironment in Pancreatic Intraepithelial Neoplasia [PDF]
, 2021 Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive tumors with a poor prognosis. A characteristic of PDAC is the formation of an immunosuppressive tumor microenvironment (TME) that facilitates bypassing of the immune surveillance.
Friederike V. Opitz +3 more
core +1 more source
Immune Cells in the Tumor Microenvironment of Soft Tissue Sarcomas [PDF]
, 2023 Soft tissue sarcomas (STSs) are a rare heterogeneous group of malignant neoplasms characterized by their aggressive course and poor response to treatment. This determines the relevance of research aimed at studying the pathogenesis of STSs. By now, it is
Timur Fatkhudinov +4 more
core +1 more source
Adipose Tissue-Derived Extracellular Vesicles and the Tumor Microenvironment: Revisiting the Hallmarks of Cancer [PDF]
, 2021 Extracellular vesicles (EVs) are crucial elements that sustain the communication between tumor cells and their microenvironment, and have emerged as a widespread mechanism of tumor formation and metastasis.
Carol Encarnação +7 more
core +1 more source
Cell Death and Disease, 2022 Aerobic glycolysis (the Warburg effect) has been demonstrated to facilitate tumor progression by producing lactate, which has important roles as a proinflammatory and immunosuppressive mediator.
Huimin Jiang +11 more
doaj +1 more source
Lipid-loaded macrophages as new therapeutic target in cancer
Journal for ImmunoTherapy of Cancer, 2022 Macrophages are main players of the innate immune system. They show great heterogeneity and play diverse functions that include support to development, sustenance of tissue homeostasis and defense against infections.
Ping-Chih Ho +7 more
doaj +1 more source
Role of tumor necrosis factor-alpha in zebrafish retinal neurogenesis and myelination [PDF]
International Journal of Ophthalmology, 2016 AIM: To investigate the role of tumor necrosis factor-alpha (TNF-α) in zebrafish retinal development and myelination. METHODS: Morpholino oligonucleotides (MO), which are complementary to the translation start site of the wild-type embryonic zebrafish ...
Xu-Dan Lei +5 more
doaj +1 more source