Results 11 to 20 of about 1,857,357 (268)
Review of the Tumor Microenvironment in Basal and Squamous Cell Carcinoma [PDF]
, 2023 It is widely known that tumor cells of basal and squamous cell carcinoma interact with the cellular and acellular components of the tumor microenvironment to promote tumor growth and progression. While this environment differs for basal and squamous cell
Stafford, Haleigh +15 more
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The emerging roles of MAPK-AMPK in ferroptosis regulatory network
Cell Communication and Signaling, 2023 Ferroptosis, a newform of programmed cell death, driven by peroxidative damages of polyunsaturated-fatty-acid-containing phospholipids in cellular membranes and is extremely dependent on iron ions, which is differs characteristics from traditional cell ...
Xinyue Wang +4 more
doaj +1 more source
Engineering the tumor microenvironment of colorectal cancer [PDF]
, 2014 The tumor microenvironment contributes significantly to the clinical prognosis, especially in CRC. Infiltration by cells from the adaptive immune system (e.g. CD8) has been linked to a better survival independently of TNM-stage.
Hirt, Christian Kurt
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Effects of Exosomal Viral Components on the Tumor Microenvironment
, 2022 SIMPLE SUMMARY: Oncogenic viral infection may lead to cancers, such as nasopharyngeal carcinoma, hepatocellular carcinoma, and cervical cancer. In addition to the tumor cells themselves, the tumor microenvironment also plays a decisive role in tumor ...
Jing Li +5 more
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The Breast Tumor Microenvironment: A Key Player in Metastatic Spread
, 2021 The tumor microenvironment plays a pivotal role in the tumorigenesis, progression, and metastatic spread of many cancers including breast. There is now increasing evidence to support the observations that a bidirectional interplay between breast cancer ...
Barbara E. Nickel +7 more
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Tumor-Suppressive Effect of Metformin via the Regulation of M2 Macrophages and Myeloid-Derived Suppressor Cells in the Tumor Microenvironment of Colorectal Cancer [PDF]
, 2022 SIMPLE SUMMARY: The tumor suppressing effect of metformin has been reported, and tumor microenvironment including immune cells contribute to tumor progression in colorectal cancer.
Lee, Kyoung Jin +27 more
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The Role of Indoleamine 2, 3-Dioxygenase 1 in Regulating Tumor Microenvironment
, 2022 SIMPLE SUMMARY: Tumor microenvironment is a complex and dynamically changing entity, which is crucial for tumor development. Indoleamine 2, 3-dioxygenase 1 is elevated in the tumor microenvironment and is strongly associated with tumor histological ...
Xiaobo Wang +7 more
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Firing up the cold tumors by targeting Vps34
OncoImmunology, 2020 Cancer immunotherapy based on anti-PD-1/PD-L1 blockade is particularly effective in responding to patients with hot tumors. These tumors are characterized by the accumulation of proinflammatory cytokines and T cell infiltration.
Bassam Janji +4 more
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The Role of Neural Signaling in the Pancreatic Cancer Microenvironment
, 2022 Pancreatic cancer is one of the most lethal malignant diseases. Various cells in the tumor microenvironment interact with tumor cells and orchestrate to support tumor progression.
Ryota Takahashi +5 more
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Cell Death and Disease, 2022 Aerobic glycolysis (the Warburg effect) has been demonstrated to facilitate tumor progression by producing lactate, which has important roles as a proinflammatory and immunosuppressive mediator.
Huimin Jiang +11 more
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