Results 11 to 20 of about 1,719,424 (316)
Review of the Tumor Microenvironment in Basal and Squamous Cell Carcinoma [PDF]
, 2023 It is widely known that tumor cells of basal and squamous cell carcinoma interact with the cellular and acellular components of the tumor microenvironment to promote tumor growth and progression. While this environment differs for basal and squamous cell
Stafford, Haleigh +15 more
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Tumor microenvironment and progression [PDF]
Journal of Surgical Oncology, 2011 AbstractTumor blood vessels are heterogeneous, of at least six distinct types, are induced primarily by vascular endothelial growth factor‐A (VEGF‐A), and provide a potentially useful therapeutic target. Breast cancer is characterized by changes in the microenvironment that result in altered tensional homeostasis.
Dvorak, Harold F +3 more
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Zhongliu Fangzhi Yanjiu, 2022 Objective To explore the related genes that play a key regulatory role in cisplatin resistance in lung adenocarcinoma. Methods Bioinformatics methods were used to download the differentially-expressed genes between cisplatin sensitive group and drug ...
WANG Lin +5 more
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Clinical Strategies Targeting the Tumor Microenvironment of Pancreatic Ductal Adenocarcinoma
, 2022 Pancreatic cancer has a complex tumor microenvironment which engages in extensive crosstalk between cancer cells, cancer-associated fibroblasts, and immune cells. Many of these interactions contribute to tumor resistance to anti-cancer therapies.
Christine Alewine +7 more
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Telocytes in the Tumor Microenvironment
, 2021 There are several theories explaining the communication between cells in the context of tumor development. Over the years, interactions between normal and transformed cells have been observed. Generally, all types of cells make equal contributions to the formation of the tumor microenvironment - a location of primary oncogenesis.
Aleksandrovych, Veronika, Gil, Krzysztof
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The emerging roles of MAPK-AMPK in ferroptosis regulatory network
Cell Communication and Signaling, 2023 Ferroptosis, a newform of programmed cell death, driven by peroxidative damages of polyunsaturated-fatty-acid-containing phospholipids in cellular membranes and is extremely dependent on iron ions, which is differs characteristics from traditional cell ...
Xinyue Wang +4 more
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The Breast Tumor Microenvironment: A Key Player in Metastatic Spread
, 2021 The tumor microenvironment plays a pivotal role in the tumorigenesis, progression, and metastatic spread of many cancers including breast. There is now increasing evidence to support the observations that a bidirectional interplay between breast cancer ...
Barbara E. Nickel +7 more
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Engineering the tumor microenvironment of colorectal cancer [PDF]
, 2014 The tumor microenvironment contributes significantly to the clinical prognosis, especially in CRC. Infiltration by cells from the adaptive immune system (e.g. CD8) has been linked to a better survival independently of TNM-stage.
Hirt, Christian Kurt
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Cancer-Associated Fibroblasts in the Hypoxic Tumor Microenvironment
, 2022 SIMPLE SUMMARY: Cancers have regions of low oxygen concentration where hypoxia-related signaling pathways are activated. The hypoxic tumor microenvironment has been widely accepted as a hallmark of cancer and shown to be a critical factor in the ...
Yoo, Seongkyeong +9 more
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Fibrocytes in the Tumor Microenvironment [PDF]
, 2020 Tumors have long been compared to chronic wounds that do not heal, since they share many of the same molecular and cellular processes. In normal wounds, healing processes lead to restoration of cellular architecture, while in malignant tumors, these healing processes become dysregulated and contribute to growth and invasion of neoplastic cells into the
David, Roife +2 more
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