Results 11 to 20 of about 493,933 (351)
Glaucomatous neurodegeneration: An eye on tumor necrosis factor-alpha
Indian Journal of Ophthalmology, 2012 Glaucoma, a neurodegenerative disease, is currently being treated by modulation of one of its primary risk factors, the elevated intraocular pressure. Newer therapies that can provide direct neuroprotection to retinal ganglion cells are being extensively
Renu Agarwal, Puneet Agarwal
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Tumor necrosis factor-alpha in patients with alopecia areata
Indian Journal of Dermatology, 2011 Background : Alopecia areata (AA) is a common form of localized, nonscarring hair loss. It is characterized by the loss of hair in patches, total loss of scalp hair (alopecia totalis, AT), or total loss of body hair (alopecia universalis, AU).
Emina Kasumagic-Halilovic +2 more
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Tumor necrosis factor-alpha inhibitor treatment for sarcoidosis
Therapeutics and Clinical Risk Management, 2008 José Luis Callejas-Rubio, Lourdes López-Pérez, Norberto Ortego-CentenoUnit of Autoimmune Systemic Diseases, Hospital Clinico San Cecilio, Granada, SpainAbstract: Sarcoidosis is a chronic multisystem disease of unknown ...
José Luis Callejas-Rubio +2 more
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Alopecia secondary to anti-tumor necrosis factor-alpha therapy [PDF]
Anais Brasileiros de Dermatologia, 2015 Biologic drugs represent a substantial progress in the treatment of chronic inflammatory immunologic diseases. However, its crescent use has revealed seldom reported or unknown adverse reactions, mainly associated with anti-tumor necrosis factor (anti ...
Lara Beatriz Prata Ribeiro +5 more
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Tumor Necrosis Factor-Alpha and Mast Cells: Revisited Study
European Journal of Inflammation, 2011 Mast cells reside in connective tissues and are widely recognized as effector cells important in innate and acquired immunity. These cells are the only ones capable of storing preformed TNFα in their cytoplasmatic granules and release upon activation ...
A. Saggini +18 more
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Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity [PDF]
Mediators of Inflammation, 2014 Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine that exerts both homeostatic and pathophysiological roles in the central nervous system.
Gabriel Olmos, Jerònia Lladó
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Epigenetic Regulation of Tumor Necrosis Factor Alpha [PDF]
Molecular and Cellular Biology, 2007 Tumor necrosis factor alpha (TNF-alpha) is a potent cytokine which regulates inflammation via the induction of adhesion molecules and chemokine expression. Its expression is known to be regulated in a complex manner with transcription, message turnover, message splicing, translation, and protein cleavage from the cell surface all being independently ...
Kelly Dietzmann +6 more
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A human inhibitor of tumor necrosis factor alpha. [PDF]
The Journal of experimental medicine, 1988 Urine of some febrile patients exhibits a TNF-alpha inhibitory activity (TNF-alpha INH), sensitive to heat and trypsin, with an apparent mol wt of 40-60 X 10(3) and a pI range of 5.5-6.1. As for the Il-1 INH, the TNF INH activity involves a competitive mechanism of action suggesting the existence of a family of negative feedback-regulating molecules ...
S Isaaz, P Seckinger, J M Dayer
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Placental-mediated increased cytokine response to lipopolysaccharides: a potential mechanism for enhanced inflammation susceptibility of the preterm fetus. [PDF]
, 2012 BackgroundCerebral palsy is a nonprogressive motor impairment syndrome that has no effective cure. The etiology of most cases of cerebral palsy remains unknown; however, recent epidemiologic data have demonstrated an association between fetal neurologic ...
Belkacemi, Louiza +4 more
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Journal of the American College of Cardiology, 2000 We determined whether tumor necrosis factor-alpha-converting enzyme (TACE) is expressed with tumor necrosis factor-alpha (TNF-alpha) in myocarditis.Tumor necrosis factor-alpha-converting enzyme, which has recently been identified as belonging to the family of metalloproteinase disintegrin proteins, is responsible for the conversion of TNF-alpha ...
Hidenori Saitoh +5 more
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