Results 21 to 30 of about 493,933 (351)
Tumor necrosis factor alpha and mesangial cells
Kidney International, 1992 Bacterial infections promote important alterations in immune, hemodynamic, and metabolic function which can result in irreversible shock. These changes are mediated by host-secreted cytokines rather than by direct action of the endotoxin lipopolysaccharide (LPS) derived from the cell wall of bacteria.
Carole Philippe +3 more
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The role of tumor necrosis factor-α and natural killer cells in uterine artery function and pregnancy outcome in the stroke prone spontaneously hypertensive rat [PDF]
, 2016 Women with chronic hypertension are at increased risk of maternal and fetal morbidity and mortality. We have previously characterized the stroke-prone spontaneously hypertensive rat (SHRSP) as a model of deficient uterine artery function and adverse ...
Beattie, Elisabeth +6 more
core +1 more source
Role of tumor necrosis factor-α and its receptors in diesel exhaust particle-induced pulmonary inflammation [PDF]
, 2017 Inhalation of diesel exhaust particles (DEP) induces an inflammatory reaction in the lung. However, the underlying mechanisms remain to be elucidated. Tumor necrosis factor alpha (TNF-alpha) is a proinflammatory cytokine that operates by binding to tumor
Boon, Louis +5 more
core +3 more sources
Eicosanoids and tumor necrosis factor-alpha in the kidney [PDF]
Prostaglandins & Other Lipid Mediators, 2012 The thick ascending limb of Henle's loop (TAL) is capable of metabolizing arachidonic acid (AA) by cytochrome P450 (CYP450) and cyclooxygenase (COX) pathways and has been identified as a nephron segment that contributes to salt-sensitive hypertension. Previous studies demonstrated a prominent role for CYP450-dependent metabolism of AA to products that ...
Ferreri, Nicholas R. +4 more
openaire +6 more sources
ALPHA TUMOR NECROSIS – AS PREDICTIVE FACTOR IN DENTAL IMPLANT MANAGEMENT
Romanian Journal of Oral Rehabilitation, 2022 Introduction. The studies regarding the involvement of TNF-alpha together with other pro-inflammatory cytokines in the occurrence and progression of peri-implantitis is of particular importance in the perspective of making an early diagnosis regarding ...
Marcel-Lucian Dobresu +7 more
doaj
Journal of Medical Case Reports, 2012 Introduction Treatment with various biological agents in disease states such as rheumatoid arthritis has been associated with multiple side effects. Whereas many of these are frequently reported in the literature, hypoglycemia, a possible side effect of ...
Czajkowska Jadwiga B +2 more
doaj +1 more source
Tumor Necrosis Factor Alpha-Mediated Asthma? [PDF]
International Archives of Allergy and Immunology, 2012 Thus the pathophysiology of allergic asthma is traditionally explained by mast celland/or Th2 cell-mediated airway inflammation, which is a manifestation of the acquired immune response. On the other hand, recent studies have identified various other important molecules associated with phenotypes of asthma, including tumor necrosis factor (TNF)[2, 3] ,
openaire +3 more sources
Targeting Tumor Necrosis Factor Alpha for Alzheimer’s Disease [PDF]
Current Alzheimer Research, 2017 Alzheimer’s disease (AD) affects an estimated 44 million individuals worldwide, yet no therapeutic intervention is available to stop the progression of the dementia. Neuropathological hallmarks of AD are extracellular deposits of amyloid beta (Aβ) peptides assembled in plaques, intraneuronal accumulation of hyperphosphorylated tau protein forming ...
Decourt, Boris +2 more
openaire +3 more sources
Revista Brasileira de Hematologia e Hemoterapia, 2014 Background: Sickle cell anemia is a chronic inflammatory disease characterized by an increased production of proinflammatory cytokines including tumor necrosis factor-alpha.
Marília Rocha Laurentino +5 more
doaj +1 more source
Tumor necrosis factor inhibitors in psoriatic arthritis. [PDF]
, 2017 INTRODUCTION: Psoriatic arthritis (PsA) is a chronic inflammatory disease that can result in significant disability. With the emergence of tumor necrosis factor inhibitors (TNFi), therapeutic outcomes in PsA have improved substantially.
Kraft, Walter K. +2 more
core +2 more sources