Results 21 to 30 of about 648,894 (406)
Serum tumor necrosis factor alpha increased during remission with Etanercept [PDF]
Pediatric Rheumatology Online Journal, 2011 Miu Nicolae +3 more
doaj +4 more sources
Central nervous system effects of tumor necrosis factor alpha blockade [PDF]
Journal of Translational Medicine, 2011 Schett Georg
doaj +4 more sources
Tumor necrosis factor alpha in sleep regulation.
Sleep Medicine Reviews, 2017 This review details tumor necrosis factor alpha (TNF) biology and its role in sleep, and describes how TNF medications influence sleep/wake activity. Substantial evidence from healthy young animals indicates acute enhancement or inhibition of endogenous brain TNF respectively promotes and inhibits sleep.
M. Rockstrom +6 more
semanticscholar +5 more sources
International Journal of Molecular Sciences, 2021 Tumor necrosis factor alpha (TNF-α) was initially recognized as a factor that causes the necrosis of tumors, but it has been recently identified to have additional important functions as a pathological component of autoimmune diseases. TNF-α binds to two
Dan-in Jang +7 more
semanticscholar +1 more source
Frontiers in Pharmacology, 2023 Objective: Tumor necrosis factor alpha inhibitors (TNFi) have shown substantial efficacy in alleviating and treating ankylosing spondylitis (AS). However, the heightened interest is accompanied by concerns over adverse events.
Haihuan Feng +7 more
doaj +1 more source
Nonlinear simulation of vascular tumor growth with chemotaxis and the control of necrosis [PDF]
Journal of Computational Physics Volume 459, 15 June 2022, 111153, 2021 In this paper, we develop a sharp interface tumor growth model in two dimensions to study the effect of both the intratumoral structure using a controlled necrotic core and the extratumoral nutrient supply from vasculature on tumor morphology. We first show that our model extends the benchmark results in the literature using linear stability analysis ...
arxiv +1 more source
Epigenetic Regulation of Tumor Necrosis Factor Alpha [PDF]
Molecular and Cellular Biology, 2007 Tumor necrosis factor alpha (TNF-alpha) is a potent cytokine which regulates inflammation via the induction of adhesion molecules and chemokine expression. Its expression is known to be regulated in a complex manner with transcription, message turnover, message splicing, translation, and protein cleavage from the cell surface all being independently ...
Kelly Dietzmann +6 more
openaire +3 more sources
Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent.
New England Journal of Medicine, 2001 BACKGROUND Infliximab is a humanized antibody against tumor necrosis factor alpha (TNF-alpha) that is used in the treatment of Crohn's disease and rheumatoid arthritis. Approximately 147,000 patients throughout the world have received infliximab.
J. Keane +7 more
semanticscholar +2 more sources
PLoS Biology, 2020 Tumor necrosis factor-alpha (TNF-α) plays an important pathogenic role in cardiac hypertrophy and heart failure (HF); however, anti-TNF is paradoxically negative in clinical trials and even worsens HF, indicating a possible protective role of TNF-α in HF.
Kun Miao +9 more
doaj +1 more source
Tumor Necrosis Factor-Alpha and Age-Related Pathologies
Архивъ внутренней медицины, 2020 Modern concepts about the «inflammaging» and the role of subclinical inflammation in various age-associated pathology are described in the review. Particular attention is paid to the tumor necrosis factor-α, a key cytokine that plays an important role in
S. V. Topolyanskaya
doaj +1 more source