Results 31 to 40 of about 693,338 (390)
Role of tumor necrosis factor-α and its receptors in diesel exhaust particle-induced pulmonary inflammation [PDF]
Inhalation of diesel exhaust particles (DEP) induces an inflammatory reaction in the lung. However, the underlying mechanisms remain to be elucidated. Tumor necrosis factor alpha (TNF-alpha) is a proinflammatory cytokine that operates by binding to tumor
Boon, Louis+5 more
core +3 more sources
Eicosanoids and tumor necrosis factor-alpha in the kidney [PDF]
The thick ascending limb of Henle's loop (TAL) is capable of metabolizing arachidonic acid (AA) by cytochrome P450 (CYP450) and cyclooxygenase (COX) pathways and has been identified as a nephron segment that contributes to salt-sensitive hypertension. Previous studies demonstrated a prominent role for CYP450-dependent metabolism of AA to products that ...
Ferreri, Nicholas R.+4 more
openaire +6 more sources
ALPHA TUMOR NECROSIS – AS PREDICTIVE FACTOR IN DENTAL IMPLANT MANAGEMENT
Introduction. The studies regarding the involvement of TNF-alpha together with other pro-inflammatory cytokines in the occurrence and progression of peri-implantitis is of particular importance in the perspective of making an early diagnosis regarding ...
Marcel-Lucian Dobresu+7 more
doaj
Introduction Treatment with various biological agents in disease states such as rheumatoid arthritis has been associated with multiple side effects. Whereas many of these are frequently reported in the literature, hypoglycemia, a possible side effect of ...
Czajkowska Jadwiga B+2 more
doaj +1 more source
Tumor Necrosis Factor Alpha-Mediated Asthma? [PDF]
Thus the pathophysiology of allergic asthma is traditionally explained by mast celland/or Th2 cell-mediated airway inflammation, which is a manifestation of the acquired immune response. On the other hand, recent studies have identified various other important molecules associated with phenotypes of asthma, including tumor necrosis factor (TNF)[2, 3] ,
openaire +3 more sources
Tumor necrosis factor inhibitors in psoriatic arthritis. [PDF]
INTRODUCTION: Psoriatic arthritis (PsA) is a chronic inflammatory disease that can result in significant disability. With the emergence of tumor necrosis factor inhibitors (TNFi), therapeutic outcomes in PsA have improved substantially.
Kraft, Walter K.+2 more
core +2 more sources
Evaluation of Tumor Necrosis Factor Alpha Polymorphism Frequencies in Endometriosis [PDF]
Background The pro-inflammatory cytokine, tumor necrosis factor-alpha (TNF-α), is a pathogenic element for a number of disorders. Previous studies have reported that the -1031 T/C and -238 G/A polymorphisms in the promoter region of the TNF-α gene are ...
Roshanak Abutorabi+4 more
doaj +1 more source
FK 506 pre-treatment is associated with reduced levels of tumor necrosis factor and interleukin 6 following hepatic ischemia/reperfusion [PDF]
Using a rat model, the effect of pre-treatment with FK 506 on hepatic ischemia/reperfusion injury was investigated. All control animals died within 72 h of the ischemia/reperfusion injury.
Aarden+64 more
core +1 more source
Background: Sickle cell anemia is a chronic inflammatory disease characterized by an increased production of proinflammatory cytokines including tumor necrosis factor-alpha.
Marília Rocha Laurentino+5 more
doaj +1 more source
Visceral Adipose Tissue Inflammatory Factors (TNF-Alpha, SOCS3) in Gestational Diabetes (GDM): Epigenetics as a Clue in GDM Pathophysiology [PDF]
Gestational diabetes (GDM) is among the most challenging diseases in westernized countries, affecting mother and child, immediately and in later life. Obesity is a major risk factor for GDM.
Henrich, Wolfgang+6 more
core +1 more source