Results 1 to 10 of about 194,634 (113)

miR-29a suppresses MCF-7 cell growth by downregulating tumor necrosis factor receptor 1

Tumor Biology, 2017
Tumor necrosis factor receptor 1 is the main receptor mediating many tumor necrosis factor-alpha–induced cellular events. Some studies have shown that tumor necrosis factor receptor 1 promotes tumorigenesis by activating nuclear factor-kappa B signaling ...
Yiling Zhao, Fenghua Yang, Wenyuan Li, Chunyan Xu, Li Li, Lifei Chen, Yancui Liu, Ping Sun   +7 more
doaj   +3 more sources

Inhibition of tumor necrosis factor receptor 1 and the risk of periodontitis

Frontiers in Immunology, 2023
AimTo investigate the effect of genetically proxied inhibition of tumor necrosis factor receptor 1 (TNFR1) on the risk of periodontitis.Materials and methodsGenetic instruments were selected from the vicinity of TNFR superfamily member 1A (TNFRSF1A) gene
Zoheir Alayash, Sebastian-Edgar Baumeister, Birte Holtfreter, Thomas Kocher, Hansjörg Baurecht, Benjamin Ehmke, Stefan Lars Reckelkamm, Michael Nolde   +7 more
doaj   +2 more sources

Choroid plexus tumor necrosis factor receptor 1: A new neuroinflammatory piece of the complex Alzheimer’s disease puzzle

Neural Regeneration Research, 2019
Due to the aging of the population and despite the enormous scientific effort, Alzheimer’s disease remains one of the biggest medical and pharmaceutical challenges in current medicine.
Sophie Steeland, Roosmarijn E Vandenbroucke   +1 more
doaj   +2 more sources

MicroRNA-29a-3p Reduces TNFα-Induced Endothelial Dysfunction by Targeting Tumor Necrosis Factor Receptor 1

Molecular Therapy: Nucleic Acids, 2019
miR-29a-3p has been shown to be associated with cardiovascular diseases; however, the effect of miR-29a-3p on endothelial dysfunction is unclear. This study aimed to reveal the effects and mechanisms of miR-29a-3p on endothelial dysfunction.
Xinrui Deng, Xia Chu, Peng Wang, Xiaohui Ma, Chunbo Wei, Changhao Sun, Jianjun Yang, Ying Li   +7 more
doaj   +2 more sources

Activation of tumor necrosis factor receptor 1 in airway smooth muscle: a potential pathway that modulates bronchial hyper-responsiveness in asthma?

Respiratory Research, 2000
The cellular and molecular mechanisms that are involved in airway hyper-responsiveness are unclear. Current studies suggest that tumor necrosis factor (TNF)-α, a cytokine that is produced in considerable quantities in asthmatic airways, may potentially ...
Panettieri Reynold A, Chen Hang, Amrani Yassine   +2 more
doaj   +2 more sources

Features of changes in the expression level of TNFα receptors and the functional response of cell lines upon stimulation with various doses of cytokine

Медицинская иммунология, 2023
TNFa is a pro-inflammatory cytokine that is signaled through type 1 (TNFR1) and type 2 (TNFR2) receptors. TNFR1 normally mediates apoptosis, cell survival, and cytokine secretion, while TNFR2 selectively mediates cell survival and cytokine secretion. But
Yu. A. Lopatnikova, Yu. V. Zhukova, A. A. Alshevskaya, I. A. Obleukhova, F. D. Kireev, I. A. Belomestnova, S. V. Sennikov   +6 more
doaj   +1 more source

Expression of tumor necrosis factor-alpha receptor 2 and interleukin-1 in middle ear cholesteatoma [PDF]

Vojnosanitetski Pregled, 2021
Background/Aim. Cholesteatoma is characterized by progressive growth with the erosion of surrounding bone due to pressure effects, enzymatic activity and activation of osteoclasts.
Vranješ Dalibor, Spremo Slobodan, Gajanin Radoslav, Špirić Sanja, Amidžić Ljiljana, Novaković-Bursać Snježana   +5 more
doaj   +1 more source

Nidogen 1‐Enriched Extracellular Vesicles Facilitate Extrahepatic Metastasis of Liver Cancer by Activating Pulmonary Fibroblasts to Secrete Tumor Necrosis Factor Receptor 1

Advancement of science, 2020
In hepatocellular carcinoma (HCC) patients with extrahepatic metastasis, the lung is the most frequent site of metastasis. However, how the lung microenvironment favors disseminated cells remains unclear.
X. Mao, S. K. Tey, Cherlie Lot Sum Yeung, Ernest Man Lok Kwong, Y. Fung, C. Chung, Lung-Yi Mak, D. Wong, Man-Fung Yuen, J. Ho, H. Pang, M. Wong, C. Leung, T. Lee, Victor Ma, W. Cho, P. Cao, Xiao-Ping Xu, Yi Gao, J. Yam   +19 more
semanticscholar   +1 more source

High Serum Tumor Necrosis Factor Receptor 1 Levels Are Related to Risk of Low Intrinsic Capacity in Elderly Adults

The Journal of Nutrition, Health & Aging, 2020
To explore the association between inflammatory cytokines and intrinsic capacity in older adults. Data were retrieved from the Cardiovascular Health, Cognition and Aging Study. A total of 130 participants aged 60–99 years (mean age 73.11±9.02 years) were
Li-Na Ma, Pan Liu, Ya-Xin Zhang, G. Sha, Li Zhang, Yun Li   +5 more
semanticscholar   +1 more source

Impact of Tumor Necrosis Factor Receptor 1 (TNFR1) Polymorphism on Dry Eye Disease

Biomolecules, 2023
The goal of the study was to examine whether a genetic polymorphism in tumor necrosis factor receptor 1 (TNFR1) gene impacted the dry eye disease (DED) phenotype and response to anti-inflammatory therapy.
Kelly Acuna, Anjalee Choudhary, Elyana Locatelli, Daniel A. Rodriguez, Eden R. Martin, Roy C. Levitt, Anat Galor   +6 more
doaj   +1 more source