Results 11 to 20 of about 29,380,860 (288)

Tumor necrosis factor receptor 2 as a possible marker of COPD in smokers and ex-smokers [PDF]

International Journal of COPD, 2017
Laura Miranda de Oliveira Caram,1 R Ferrari,1 DL Nogueira,1 MRM Oliveira,2 FV Francisqueti,2 SE Tanni,1 CR Corrêa,2 I Godoy1 1Department of Internal Medicine, 2Department of Pathology, Botucatu Medical School, UNESP – Univ Estadual Paulista,
Caram LMO, Ferrari R, Nogueira DL, Oliveira MRM, Francisqueti FV, Tanni SE, Corrêa CR, Godoy I   +7 more
doaj   +3 more sources

An Autocrine TNFα–Tumor Necrosis Factor Receptor 2 Loop Promotes Epigenetic Effects Inducing Human Treg Stability In Vitro [PDF]

Frontiers in Immunology, 2018
A crucial issue for Treg-based immunotherapy is to maintain a bona fide Treg phenotype as well as suppressive function during and after ex vivo expansion. Several strategies have been applied to harness Treg lineage stability.
Paulo C. M. Urbano, Hans J. P. M. Koenen, Irma Joosten, Xuehui He, Xuehui He   +4 more
doaj   +2 more sources

Expression of Tumor Necrosis Factor Receptor 2 Characterizes TLR9-Driven Formation of Interleukin-10-Producing B Cells [PDF]

Frontiers in Immunology, 2018
B cell-derived interleukin-10 (IL-10) production has been described as a hallmark for regulatory function in B lymphocytes. However, there is an ongoing debate on the origin of IL-10-secreting B cells and lack of specific surface markers has turned into ...
Olga Ticha, Lukas Moos, Harald Wajant, Isabelle Bekeredjian-Ding   +3 more
doaj   +2 more sources

Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration. [PDF]

Proc Natl Acad Sci U S A, 2016
Significance TNF is known to play an important role in various neurodegenerative diseases. However, anti-TNF therapeutics failed in clinical trials of neurodegenerative diseases. This failure is most likely due to antithetic effects of the TNF receptors in the central nervous system, whereby TNFR1 promotes inflammatory degeneration ...
Dong Y, Fischer R, Naudé PJ, Maier O, Nyakas C, Duffey M, Van der Zee EA, Dekens D, Douwenga W, Herrmann A, Guenzi E, Kontermann RE, Pfizenmaier K, Eisel UL.   +13 more
europepmc   +6 more sources

Relationship between Maternal Retinal Microvascular Changes in the Postpartum Period, Tumor Necrosis Factor Receptor 2, and Cotinine [PDF]

Biomedicine Hub
Introduction: During pregnancy, placental microvasculature undergoes significant adaptations to support the developing fetus. However, studying placental microcirculation in vivo remains challenging.
Yogavijayan Kandasamy, Rachel Lim, Jean Calleja-Agius, Donna Rudd   +3 more
doaj   +2 more sources

Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study [PDF]

Frontiers in Pharmacology, 2018
Background: Transmembrane tumor necrosis factor (TNF) receptors are involved in inflammatory, apoptotic, and proliferative processes. In the bloodstream, soluble TNF receptor II (sTNFR2) can modify the inflammatory response of immune cells and is ...
Michael M. Mendelson, Michael M. Mendelson, Michael M. Mendelson, Roby Johannes, Chunyu Liu, Chunyu Liu, Tianxiao Huan, Tianxiao Huan, Chen Yao, Chen Yao, Xiao Miao, Joanne M. Murabito, Joanne M. Murabito, Josée Dupuis, Josée Dupuis, Daniel Levy, Daniel Levy, Emelia J. Benjamin, Emelia J. Benjamin, Emelia J. Benjamin, Honghuang Lin, Honghuang Lin   +21 more
doaj   +2 more sources

Role of the Interaction of Tumor Necrosis Factor-α and Tumor Necrosis Factor Receptors 1 and 2 in Bone-Related Cells [PDF]

International Journal of Molecular Sciences, 2022
Tumor necrosis factor-α (TNF-α) is a pleiotropic cytokine expressed by macrophages, monocytes, and T cells, and its expression is triggered by the immune system in response to pathogens and their products, such as endotoxins. TNF-α plays an important role in host defense by inducing inflammatory reactions such as phagocytes and cytocidal systems ...
Hideki Kitaura, Aseel Marahleh, Fumitoshi Ohori, Takahiro Noguchi, Yasuhiko Nara, Adya Pramusita, Ria Kinjo, Jinghan Ma, Kayoko Kanou, Itaru Mizoguchi   +9 more
openaire   +2 more sources

Features of changes in the expression level of TNFα receptors and the functional response of cell lines upon stimulation with various doses of cytokine

Медицинская иммунология, 2023
TNFa is a pro-inflammatory cytokine that is signaled through type 1 (TNFR1) and type 2 (TNFR2) receptors. TNFR1 normally mediates apoptosis, cell survival, and cytokine secretion, while TNFR2 selectively mediates cell survival and cytokine secretion. But
Yu. A. Lopatnikova, Yu. V. Zhukova, A. A. Alshevskaya, I. A. Obleukhova, F. D. Kireev, I. A. Belomestnova, S. V. Sennikov   +6 more
doaj   +1 more source

Expression of tumor necrosis factor-alpha receptor 2 and interleukin-1 in middle ear cholesteatoma [PDF]

Vojnosanitetski Pregled, 2021
Background/Aim. Cholesteatoma is characterized by progressive growth with the erosion of surrounding bone due to pressure effects, enzymatic activity and activation of osteoclasts.
Vranješ Dalibor, Spremo Slobodan, Gajanin Radoslav, Špirić Sanja, Amidžić Ljiljana, Novaković-Bursać Snježana   +5 more
doaj   +1 more source

Choroid plexus tumor necrosis factor receptor 1: A new neuroinflammatory piece of the complex Alzheimer’s disease puzzle

Neural Regeneration Research, 2019
Due to the aging of the population and despite the enormous scientific effort, Alzheimer’s disease remains one of the biggest medical and pharmaceutical challenges in current medicine.
Sophie Steeland, Roosmarijn E Vandenbroucke   +1 more
doaj   +1 more source