Results 201 to 210 of about 1,355,842 (299)

Unlocking the Therapeutic Potential of Integrin-Linked Kinase Inhibitors in Bioengineered 3D Breast Tumor Stroma Models. [PDF]

FASEB J
Rafik ST, Upadhyay A, MacRobert AJ, Cheema U.   +3 more
europepmc   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Tumor stroma ratio-based radiomics model for predicting platinum resistance and prognosis in epithelial ovarian cancer. [PDF]

J Ovarian Res
Xiang W, Guo H, Sun Y, Jin X, Li H, Xia S.   +5 more
europepmc   +1 more source

The Prognostic Role of CD8+ Tumor‐Infiltrating Lymphocyte Density in Head and Neck Mucosal Melanoma

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To explore the prognostic role of CD8+ tumor‐infiltrating lymphocytes (TIL) density in head and neck mucosal melanoma (HNMM) using an automated, quantitative, immunohistochemistry‐based methodology. Study Design Retrospective cohort study. Setting Single‐institution, tertiary care hospital.
Nicholas K. Fung, Douglas Hartman, Diwakar Davar, Eric W. Wang   +3 more
wiley   +1 more source

Epstein-Barr Virus Infection Is Associated with an Elevated Tumor-Stroma Ratio and Older Age in Oral Squamous Cell Carcinoma. [PDF]

Viruses
Rahmadhini EN, Sufiawati I, Agustina H, Husain O, Sadputranto SA, Idris A.   +5 more
europepmc   +1 more source

A transition zone enriched WIF1+ basal cell subtype is associated with benign prostatic hyperplasia

The Journal of Pathology, EarlyView.
Abstract The cellular composition and disease susceptibilities of the distinct zones of the human prostate remain incompletely understood. Benign prostatic hyperplasia (BPH) is a common condition that causes widespread morbidity and is nearly exclusively localized to the transition zone (TZ).
Rulin Wang, Qizhi Zheng, Mindy K Graham, Ajay Vaghasia, Jianyong Liu, Jordan Gregg, Tracy Jones, Anuj Gupta, Nicole Castagna, Yan Zhang, Kornel Schuebel, Jennifer Meyers, Alyza Skaist, Dixie Hoyle, Jasmine Kung, Jessica Hicks, Alok Mishra, Yuhan Yang, William G Nelson, Angelo M De Marzo, Srinivasan Yegnasubramanian   +20 more
wiley   +1 more source

Predicting induction chemotherapy response based on tumor-stroma ratio and pretreatment synthetic MRI in nasopharyngeal carcinoma. [PDF]

Eur Radiol Exp
Ren H, Zhang X, Xu Q, Liu D, Chen X, Huang Y, Lan H, Li L, Li Y, Huang H, Sui J, Huang J, Ren X, Huang Y, Tan Y, Yu H, Shu X, Wang Y, Zhang H, Li D, Nie L, Zhang J.   +21 more
europepmc   +1 more source

A Nodule on the Cheek of a Child

JEADV Clinical Practice, EarlyView.
Monika Fida, Tedi Minarolli, Ritjana Mala, Arlin Kokomani, Leart Bërdica, Alesja Palaj   +5 more
wiley   +1 more source

CAFs‐mediated histone lactylation reprograms cholesterol metabolism in colorectal cancer to drive CD8+ T cell immunosuppression

The Journal of Pathology, EarlyView.
Abstract The progression of colorectal cancer (CRC) is critically regulated by cancer‐associated fibroblasts (CAFs) within the tumor microenvironment (TME), yet the specific molecular mechanisms by which CAFs influence CRC remain unclear. This study reveals the mechanism by which CAFs promote CRC malignant progression and immune suppression through ...
Huachi Li, Jun Hu, Lei Huang, Zihao Wang, Haoran Tao, Feng Cao, Min Xie   +6 more
wiley   +1 more source