Results 261 to 270 of about 1,355,842 (299)
Some of the next articles are maybe not open access.
Anticancer research, 2000
The accumulated evidence indicates that tumor stroma with its cells and cell products plays a much more active and important role than previously believed. Growth factors and cytokines produced by macrophages and other cells are crucial for stroma formation and angiogenesis. Lytic enzymes provided by stromal cells may be essential for invasion. TNF and
R, Seljelid +2 more
openaire +1 more source
The accumulated evidence indicates that tumor stroma with its cells and cell products plays a much more active and important role than previously believed. Growth factors and cytokines produced by macrophages and other cells are crucial for stroma formation and angiogenesis. Lytic enzymes provided by stromal cells may be essential for invasion. TNF and
R, Seljelid +2 more
openaire +1 more source
Tumors with Functioning Stroma
2013These are tumors other than those in the sex cord-stromal and steroid cell categories that are characterized [1] by (1) a stroma that is morphologically compatible with steroid hormone secretion and (2) clinical biochemical or pathologic incidence of endocrine abnormalities [2] of estrogenic androgenic or rarely progestogenic type, or a combination of ...
Jean Noel Buy, Michel Ghossain
openaire +1 more source
Therapeutic targeting of tumor–stroma interactions
Expert Opinion on Therapeutic Targets, 2011Cancers exist within a complex microenvironment populated by diverse cell types within a protein-rich extracellular matrix. It is becoming increasingly apparent that molecular interactions between epithelial cells and cells in the surrounding stroma promote growth, invasion and spread of the tumor itself and thus represents a crucial underlying driving
Stephen, Hiscox +2 more
openaire +2 more sources
Effects of Photodynamic Therapy on Tumor Stroma
Ultrastructural Pathology, 2004Photodynamic therapy (PDT) is a treatment that combines a photosensitizer with light to generate oxygen-dependent photochemical destruction of diseased tissue. This modality has been approved worldwide since 1993 for the treatment of several oncological and nononcological disorders.
Qian, Peng, Jahn M, Nesland
openaire +2 more sources
Hypoxia as a regulator of tumor stroma and metastasis
American Journal of Physiology-Cell Physiology, 2023Metastasis is the leading cause of mortality in most patients with cancer. Despite its clinical importance, mechanistic underpinnings of metastatic progression remain poorly understood. Hypoxia, a condition of insufficient oxygen availability, frequently occurs in solid tumors because of their high oxygen/nutrient demand and abnormal tumor vasculature.
openaire +2 more sources
Influences of tumor stroma on the malignant phenotype
Journal of Oral Pathology & Medicine, 2008Background: The microenvironment makes a significant contribution to the progression of oral carcinomas. Many different stromal events, such as vascularization, fibroblast activation, myofibroblast differentiation, and the presence of specific stromal proteins, such as proteolytic enzymes, fibronectin and laminin 5 are all characteristics of the tumor
Nielsen, Jørgen Dau +3 more
openaire +3 more sources
2007
In addition to their well-documented roles in leukemia and lymphoma, cytokines and chemokines can directly affect the progression of solid tumors, including carcinomas (1–3). Carcinomas are the most frequent human tumors that arise from the epithelial cells that line the inner surfaces of organs.
openaire +1 more source
In addition to their well-documented roles in leukemia and lymphoma, cytokines and chemokines can directly affect the progression of solid tumors, including carcinomas (1–3). Carcinomas are the most frequent human tumors that arise from the epithelial cells that line the inner surfaces of organs.
openaire +1 more source
Bulletin du cancer, 2008
It is widely accepted that the development of carcinoma is not only due to somatic mutations in epithelial cells but also is influenced by the tumor microenvironment ie the stroma. The different stroma components produced growth factors, cytokines, the extra cellular matrix and also participated to the recruitment of the endothelial cells necessary for
Clotilde, Billottet +1 more
openaire +1 more source
It is widely accepted that the development of carcinoma is not only due to somatic mutations in epithelial cells but also is influenced by the tumor microenvironment ie the stroma. The different stroma components produced growth factors, cytokines, the extra cellular matrix and also participated to the recruitment of the endothelial cells necessary for
Clotilde, Billottet +1 more
openaire +1 more source
3D In Vitro Model (R)evolution: Unveiling Tumor–Stroma Interactions
Trends in Cancer, 2021Liliana Teixeira +2 more
exaly