Results 251 to 260 of about 1,355,842 (299)

Short cold atmospheric plasma treatment preserves vascular quiescence in 3D tumor-stroma-endothelial models of pancreatic cancer in vitro and in ovo. [PDF]

NPJ Precis Oncol
Verloy R, Peeters E, Privat-Maldonado A, Rovers S, Lau HW, Brants L, Hermans C, De Waele J, Deben C, Smits E, Bogaerts A.   +10 more
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Tumor-Stroma interactions

, 2010
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Tumor Stroma Manipulation By MSC

Current Drug Targets, 2016
Tumor stroma (TS) plays relevant roles in all steps of cancer development. We here address several fundamental aspects related with the interaction between cancer cells and their stromal counterparts. Dissecting these players is of pivotal importance to understand oncogenesis, immunoescape and drug resistance.
GRISENDI, Giulia, Spano, Carlotta, ROSSIGNOLI, FILIPPO, D. Souza, Naomi, GOLINELLI, GIULIA, Fiori, Agnese, Horwitz, Edwin M, Guarneri, Valentina, PIACENTINI, Federico, Paolucci, Paolo, DOMINICI, Massimo   +10 more
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Tumor–stroma crosstalk

Current Opinion in Oncology, 2014
Combinatorial strategies in cancer medicine will not only target cancer cell-intrinsic pathways, but also cancer cell-extrinsic cells, pathways, and mediators of the tumor microenvironment. The aim of the present review is to define the roles of the tumor microenvironment in primary and metastatic breast cancer progression.The cancer microenvironment ...
Carmen, Criscitiello, Angela, Esposito, Giuseppe, Curigliano   +2 more
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Tumor microenvironment: The role of the tumor stroma in cancer

Journal of Cellular Biochemistry, 2007
AbstractThe tumor microenvironment, composed of non‐cancer cells and their stroma, has become recognized as a major factor influencing the growth of cancer. The microenvironment has been implicated in the regulation of cell growth, determining metastatic potential and possibly determining location of metastatic disease, and impacting the outcome of ...
Jeanmarie Houghton, Hanchen Li
exaly   +3 more sources

Tumor: Stroma Interaction and Cancer

2022
The understanding of how normal cells transform into tumor cells and progress to invasive cancer and metastases continues to evolve. The tumor mass is comprised of a heterogeneous population of cells that include recruited host immune cells, stromal cells, matrix components, and endothelial cells. This tumor microenvironment plays a fundamental role in
Michael P, Rogers, Zhiyong, Mi, Neill Y, Li, Philip Y, Wai, Paul C, Kuo   +4 more
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MicroRNA in the Tumor Stroma: Diagnostic and Therapeutic Implications

2021
In this chapter, the author highlight dysregulated MicroRNAs (miRNA), as potential therapeutic targets in different tumor stromal cells describe their functions in the regulation of the tumor microenvironment. They also discusses the role of tumor-related miRNAs as biomarkers for cancer diagnosis and prognosis.
Lu, Tao, Terstappen, Leon W.M.M., Prakash, Jai   +2 more
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Tumor Stroma as a Target in Cancer

Current Cancer Drug Targets, 2008
Solid tumors are composed of the malignant cell itself (most commonly a carcinoma) and supporting cells that comprise the stroma. Significant stromal components include the extracellular matrix, supporting fibroblasts, vessels comprised of endothelium, pericytes and in some cases vascular smooth muscle, lymphatics and usually a major leukocyte ...
F, Ahmed, J C, Steele, J M J, Herbert, N M, Steven, R, Bicknell   +4 more
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Ovarian tumor with functioning stroma

Computerized Medical Imaging and Graphics, 2002
The authors reported two cases with ovarian tumors with functioning stroma. One was an ovarian carcinoid with testosterone-producing stroma and another was an ovarian mucinous cystadenoma with elevated serum level of estrogen. They appeared as multilocular cystic masses with varying signal on MR. This imaging feature was mimicking both those of Sertoli-
Yumiko Oishi, Tanaka, Yoshihiro, Ide, Masato, Nishida, Ken, Nishide, Hajime, Tsunoda, Motonao, Kajitani, Yuji, Itai   +6 more
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Hallmarks of cancer: Interactions with the tumor stroma

Experimental Cell Research, 2010
Ten years ago, Hanahan and Weinberg delineated six "Hallmarks of cancer" which summarize several decades of intense cancer research. However, tumor cells do not act in isolation, but rather subsist in a rich microenvironment provided by resident fibroblasts, endothelial cells, pericytes, leukocytes, and extra-cellular matrix.
Kristian Pietras, Arne Östman
exaly   +3 more sources