Dermal chondrosarcoma in a cat with prolonged survival after limb amputation
A 5‐year‐old male entire domestic shorthair cat presented with a firm dermal mass on the dorsal left metatarsal region. Diagnostic investigations included haematology, biochemistry, urinalysis, biopsy, histopathology and computed tomography staging. Histopathology of the tissue biopsy, including immunohistochemistry, confirmed a dermal chondrosarcoma ...
A Ivanovs +5 more
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Tumor-stroma contributes to immunotherapeutic resistance in non-small cell lung cancer via SEMA3C-mediated immunosuppressive tumor microenvironment. [PDF]
Zhang H +8 more
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Engineered cyclic peptide targeting ITGA5 disrupts tumor-stroma interaction to overcome desmoplasia and resistance in pancreatic ductal adenocarcinoma. [PDF]
Mardhian DF +8 more
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How glioblastoma organoids are made shapes what they become. Fragment‐based cultures preserve extracellular matrix networks, cellular diversity, and primary tumor identity, whereas dissociation‐based cultures shift toward growth‐adapted states and simplified microenvironments. Abstract Patient‐derived tumor organoids are widely used in cancer research,
Jana Slovackova +11 more
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Establishment of immortalized ovarian stromal cell lines using Sendai virus vectors: a platform for studying tumor-stroma interactions and carcinogenesis. [PDF]
Okawa M +12 more
europepmc +1 more source
Brain metastasis‐associated fibroblasts are active stromal components of the metastatic niche characterised by extracellular matrix remodelling and production of pro‐migratory mediators. They promote monocyte and cancer cell migration and enhance cancer cell invasion while having no growth‐promoting effect on cancer cells.
Barbora Výmolová +19 more
wiley +1 more source
Advancing Prostate Cancer Assessment: A Biparametric MRI (T2WI and DWI/ADC)-Based Radiomic Approach to Predict Tumor-Stroma Ratio. [PDF]
Ma J +10 more
europepmc +1 more source
Resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other CNS embryonal tumors are provided. Abstract WHO CNS5 mandates integrated histo‐molecular classification of medulloblastomas (MBs) and other CNS embryonal tumors. However, advanced molecular diagnostics remain inaccessible in many low‐ and lower‐middle‐
Chitra Sarkar +12 more
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Artificial intelligence-based tumor-stroma ratio quantification reveals prognostic value and stromal-driven immunosuppression in colorectal cancer: an international validation study. [PDF]
Ye H +15 more
europepmc +1 more source
[Tumors of the endometrial stroma].
P, Escudero, E, Suárez, A, Reid
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