Results 41 to 50 of about 317,105 (146)

Improvement of a 1D Population Balance Model for Twin-Screw Wet Granulation by Using Identifiability Analysis

Pharmaceutics, 2021
Recently, the pharmaceutical industry has undergone changes in the production of solid oral dosages from traditional inefficient and expensive batch production to continuous manufacturing.
Ana Alejandra Barrera Jiménez, Daan Van Hauwermeiren, Michiel Peeters, Thomas De Beer, Ingmar Nopens   +4 more
doaj   +1 more source

Development of a Granule Growth Regime Map for Twin Screw Wet Granulation Process via Data Imputation Techniques

Pharmaceutics, 2022
Twin screw granulation (TSG) is a continuous wet granulation technique that is used widely across different solid manufacturing industries. The TSG has been recognized to have numerous advantages due to its modular design and continuous manufacturing ...
Lalith Kotamarthy, Chaitanya Sampat, Rohit Ramachandran   +2 more
doaj   +1 more source

Linking granulation performance with residence time and granulation liquid distributions in twin-screw granulation: An experimental investigation [PDF]

, 2016
Twin-screw granulation is a promising wet granulation technique for the continuous manufacturing of pharmaceutical solid dosage forms. A twin screw granulator displays a short residence time.
Remon, Jean Paul, De Beer, Thomas, Ketolainen, Jarkko, Vervaet, Chris, Gernaey, Krist V., Nopens, Ingmar, Vanhoorne, Valérie, De Leersnyder, Fien, Juuti, Mikko, Vercruysse, Jurgen, Kumar, Ashish, Alakarjula, Maija, Toiviainen, Maunu   +12 more
core   +1 more source

A one dimensional model for the prediction of extraction yields in a two phases modified twin-screw extruder [PDF]

, 2002
Solid/liquid extraction is performed on raw plant substrate with a modified twin-screw extruder (TSE) used as a thermo-mecanochemical reactor. Visual observations and experimental residence time distributions (RTD) are used to develop a solid transport ...
Prat, Laurent E., Guiraud, Pascal, Prat, Laurent, Gourdon, Christophe, Rigal, Luc   +4 more
core   +1 more source

Conceptualisation of an Efficient Particle-Based Simulation of a Twin-Screw Granulator

Pharmaceutics, 2021
Discrete Element Method (DEM) simulations have the potential to provide particle-scale understanding of twin-screw granulators. This is difficult to obtain experimentally because of the closed, tightly confined geometry.
John P. Morrissey, Kevin J. Hanley, Jin Y. Ooi   +2 more
doaj   +1 more source

Direct extraction of oil from sunflower seeds by twin-screw extruder according to an aqueous extraction process: Feasibility study and influence of operating conditions [PDF]

, 2007
The objective of this study was to evaluate the feasibility of an aqueous process to extract sunflower seed oil using a co-rotating twin-screw extruder. Aqueous extraction was carried out using whole seeds and the influence of the operating conditions on
Evon, Philippe, Pontalier, Pierre Yves, Ph. Evon, V. Vandenbossche, P.Y. Pontalier, Pontalier, Pierre-Yves, L. Rigal, Vandenbossche, Virginie, Rigal, Luc   +8 more
core   +1 more source

Pharmaceutical Application of Process Understanding and Optimization Techniques: A Review on the Continuous Twin-Screw Wet Granulation

Biomedicines, 2023
Twin-screw wet granulation (TSWG) is a method of continuous pharmaceutical manufacturing and a potential alternative method to batch granulation processes.
Jie Zhao, Geng Tian, Haibin Qu
doaj   +1 more source

Material Transport Characteristics in Planetary Roller Melt Granulation

Pharmaceutics, 2023
Melt granulation for improving material handling by modifying particle size distribution offers significant advantages compared to the standard methods of dry and wet granulation in dust reduction, obviating a subsequent drying step. Furthermore, current
Tom Lang, Andreas Bramböck, Markus Thommes, Jens Bartsch   +3 more
doaj   +1 more source

Toward Pore‐Engineered 3D‐Printed Materials for Sorption Water Harvesting, Interfacial Evaporation, and Radiative Cooling

Advanced Materials, EarlyView.
Water harvesting, radiative cooling, and interfacial solar evaporation are fundamentally governed by coupled heat, mass, and light transport processes. These processes are mediated by pore architecture, including pore size, connectivity, and hierarchical organization.
Dejan J. Trajkovski, Higgins M. Wilson, Abdallah Y. M. Ali, Jiaxing Xu, Ruzhu Wang, Primož Poredoš   +5 more
wiley   +1 more source

Concentration‐Dependent Lamellar Organization and Structure–Property Relationships in Melt‐Processed EVA/Cloisite 20A Nanocomposites

Journal of Applied Polymer Science, EarlyView.
Cloisite 20A content tunes the structural and mechanical response of melt‐processed ethylene‐vinyl acetate (EVA) nanocomposites. Expanded basal spacings at 5.0 and 7.5 wt% clay are consistent with polymer‐chain intercalation within ordered clay domains.
R. S. Victor, J. C. A. Queiroz, A. D. Oliveira, E. M. Araújo, V. S. S. Sobrinho, T. H. C. Costa, M. S. Libório, A. M. D. Leite   +7 more
wiley   +1 more source